- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Palliative Care and End-of-Life Issues
- International Relations in Latin America
- Head and Neck Surgical Oncology
- Advanced Radiotherapy Techniques
- Brain Metastases and Treatment
- Cancer survivorship and care
- Radiomics and Machine Learning in Medical Imaging
- Sarcoma Diagnosis and Treatment
- Migration and Labor Dynamics
- Bone Tumor Diagnosis and Treatments
- Immigration and Intercultural Education
- Colorectal and Anal Carcinomas
- Economic and Financial Impacts of Cancer
- Cancer Immunotherapy and Biomarkers
- Polyomavirus and related diseases
- Cancer Genomics and Diagnostics
- Nonmelanoma Skin Cancer Studies
- Business, Innovation, and Economy
- Hepatocellular Carcinoma Treatment and Prognosis
- Central Venous Catheters and Hemodialysis
- Colorectal Cancer Treatments and Studies
- Glioma Diagnosis and Treatment
University of California, Irvine
2020-2025
University of California, Irvine Medical Center
2021-2024
University of Toledo
2022
Cleveland Clinic
2022
Summa Health System
2022
Stanford Medicine
2016-2020
Cancer Institute (WIA)
2019
Stanford Cancer Institute
2019
Stanford University
2017-2019
Government of the United States of America
2015
Summary Background and objectives Comparisons of fistulas grafts often overlook the high primary failure rate fistulas. This study compared cumulative patency (time from access creation to permanent failure) grafts. Design, setting, participants, & measurements Vascular accesses 1140 hemodialysis patients two centers (Toronto London, Ontario, Canada, 2000−2010) were analyzed. Cumulative was between groups using Kaplan-Meier survival curves log-rank tests. Hazard ratios (HRs) for fistula...
Survival in mycosis fungoides (MF) is varied and may be poor. The PROCLIPI (PROspective Cutaneous Lymphoma International Prognostic Index) study a web-based data collection system for early-stage MF with legal data-sharing agreements permitting international collaboration rare cancer complex pathology. Clinicopathological must 100% complete in-built intelligence the database ensures accurate staging.
Hypofractionated radiation therapy regimens should not be used as standard of care for localized soft tissue sarcoma
The optimal management of local-regionally recurrent head and neck cancer that is not amenable to surgical resection uncertain. We sought compare outcomes among patients treated with without re-irradiation in this setting.
Randomized control trials and population-based studies do not demonstrate a definitive benefit for adjuvant chemotherapy (ACT) in stage II colon cancer (CC). Tumor sidedness microsatellite instability (MSI) status may predict response to ACT, but previous have limited data. We assessed the efficacy of ACT possible interaction with MSI tumor patients resected CC diagnosed between 2010 2013 using National Cancer Database.Overall survival was evaluated Kaplan-Meier method multivariate...
Importance The role of surveillance imaging after treatment for head and neck cancer is controversial evidence to support decision-making limited. Objective To determine the use in asymptomatic patients with remission completion chemoradiation. Design, Setting, Participants This was a retrospective, comparative effectiveness research review adult who had achieved complete metabolic response initial as defined by having an unequivocally negative positron emission tomography (PET) scan using...
Despite the recent approval of immune checkpoint inhibitors (ICIs), Merkel cell carcinoma (MCC) remains highly lethal for most patients failing out ICIs.1Nghiem P. Bhatia S. Lipson E.J. et al.Three-year survival, correlates and salvage therapies in receiving first-line pembrolizumab advanced carcinoma.J Immunother Cancer. 2021; 9e002478https://doi.org/10.1136/jitc-2021-002478Crossref Scopus (40) Google Scholar Existing biomarkers (tumor mutation burden, programmed death ligand-1 expression,...
Understanding healthcare providers' preferences, values, and beliefs around AVF eligibility is important to explain variability in practice. We conducted a survey of international surgeons, using hypothetical patient scenarios, assess resources used, variables, perceived barriers, absolute contraindications access creation. A total 134 surgeons completed the survey. Venous duplex ultrasound mapping (VDUM) was offered all patients by 90% US, 68% Canadian, 63% European respondents. VDUM...
Endovascular repair of blunt traumatic thoracic aortic injuries (BTAI) is common at most trauma centres, with excellent results. However, little known regarding which do not require intervention. We reviewed the natural history untreated patients minimal injury (MAI) our centre.
Objectives/Hypothesis To identify prognosticators and determine the efficacies of surgery with adjuvant radiotherapy (SR) immunotherapy (SI) head neck mucosal melanoma (HNMM). Study Design Retrospective database study. Methods The 2004 to 2017 National Cancer Database was queried for HNMM patients. Cox proportional hazards Kaplan‐Meier analyses evaluated mortality survival benefits conferred by SR, SI, or (SRI). Logistic regression identified predictors use. Results Overall, 1,910 cases (845...
Objective For patients with head and neck squamous cell carcinoma (HNSCC), delays in the initiation of radiotherapy (RT) have been closely associated worse outcomes. We sought to investigate whether RT modality (proton vs. photon) is differences time RT. Methods The National Cancer Database was queried for diagnosed nonmetastatic HNSCC between 2004 2015 who received either proton or photon as part their initial treatment. Wilcoxon rank‐sum chi‐square tests were used compare continuous...
To comprehensively investigate nasopharyngeal carcinoma (NPC) treatment, overall survival (OS), and the influence of clinical/sociodemographic factors on outcome.Retrospective database study.National Cancer Database.The 2004-2015 National Database was queried for all patients with NPC receiving definitive treatment. Log-rank tests Cox proportional hazards models were used statistical analyses.A total 8260 included (71.4% male; 42.5% keratinizing histology; mean ± SD age, 52.1 15.1 years), a...
Objectives Immunotherapy with immune checkpoint inhibitors has shown only limited success in the management of metastatic soft tissue sarcoma. Overall response rates (ORR) single agent pembrolizumab were 18% and median PFS was 18 weeks on clinical trial SARC028. One strategy to improve responses immunotherapy is stereotactic body radiation therapy (SBRT), which can enhance antitumor CD8 T cell through release tumor-specific antigens, potentially priming a more diverse class receptors....
Y-90 Selective Internal Radiotherapy (SIRT) is an ablative therapy used for inoperable liver metastasis. The purpose of this investigation was to examine the impact local control after SIRT on overall survival (OS) in oligometastatic patients. A retrospective, single-institution study identified patients with ≤5 non-intracranial metastases receiving unilateral or bilateral lobar from 2009 2021. primary endpoint OS defined completion date death last follow-up. Local failure classified as a...