Zhiyan Wang

ORCID: 0000-0001-7910-3245
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About
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Research Areas
  • EEG and Brain-Computer Interfaces
  • Vagus Nerve Stimulation Research
  • Diet, Metabolism, and Disease
  • Neurological disorders and treatments
  • Liver Disease Diagnosis and Treatment
  • Advancements in Battery Materials
  • Neurotransmitter Receptor Influence on Behavior
  • Parkinson's Disease Mechanisms and Treatments
  • Advanced Battery Technologies Research
  • Epilepsy research and treatment
  • Advanced Battery Materials and Technologies
  • Endoplasmic Reticulum Stress and Disease
  • Heart Rate Variability and Autonomic Control
  • Influenza Virus Research Studies
  • Advanced Fiber Laser Technologies
  • Supercapacitor Materials and Fabrication
  • Microbial Natural Products and Biosynthesis
  • Photonic and Optical Devices
  • Functional Brain Connectivity Studies
  • Orthopedic Infections and Treatments
  • Neuroscience and Neural Engineering
  • Total Knee Arthroplasty Outcomes
  • Genetic Neurodegenerative Diseases
  • Quantum many-body systems
  • Blood Pressure and Hypertension Studies

Peking University
2016-2025

Fudan University
2023-2025

Beijing Anzhen Hospital
2022-2025

Capital Medical University
2022-2025

Hunan University
2025

Institute of Psychology, Chinese Academy of Sciences
2023-2024

University of Chinese Academy of Sciences
2022-2024

Inner Mongolia University for Nationalities
2024

Shanghai Center for Brain Science and Brain-Inspired Technology
2024

Yangtze University
2018-2024

Background: Ischemic left ventricular (LV) aneurysm is associated with LV thrombus and subsequent embolic events. However, there currently no evidence-based recommendation for anticoagulation in these patients. Objective: To determine the characteristics of aneurysms a high risk formation. Methods: This retrospective study included all hospitalized patients ischemic who underwent cardiac magnetic resonance (CMR) from September 2015 to June 2023. Baseline CMR parameters were compared between...

10.1055/a-2536-8739 article EN Thrombosis and Haemostasis 2025-02-11

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification of the chloride-binding site in human red and green color vision pigmentsZhiyan Wang, Ana B. Asenjo, Daniel D. OprianCite this: Biochemistry 1993, 32, 9, 2125–2130Publication Date (Print):March 1993Publication History Published online1 May 2002Published inissue 9 March 1993https://pubs.acs.org/doi/10.1021/bi00060a001https://doi.org/10.1021/bi00060a001research-articleACS PublicationsRequest reuse permissionsArticle...

10.1021/bi00060a001 article EN Biochemistry 1993-03-09

Previous studies have documented that heightened impulsivity likely contributes to the development and maintenance of alcohol use disorders. However, there is still a lack comprehensively detected brain changes associated with abnormal in addicts. This study was designed investigate alterations structure functional connectivity dependent patients.Brain structural magnetic resonance imaging data as well impulsive behavior were collected from 20 patients age- sex-matched healthy controls...

10.1371/journal.pone.0161956 article EN cc-by PLoS ONE 2016-08-30

A simple approach using <italic>Nelumbo nucifera</italic> seeds for synthesizing silver nanoparticles with potential antibacterial and cytotoxic activities was described.

10.1039/c7nj04224h article EN New Journal of Chemistry 2018-01-01

Deep brain stimulation (DBS) is a promising therapy for treatment-resistant depression, while mechanisms underlying its therapeutic effects remain poorly defined. Increasing evidence has revealed an intimate association between the lateral habenula (LHb) and major suggests that LHb might be effective target of DBS depression. Here, we found in effectively decreased depression-like behaviors rats experienced with chronic unpredictable mild stress (CUMS), well-accepted paradigm modeling...

10.1016/j.nbd.2023.106069 article EN cc-by-nc-nd Neurobiology of Disease 2023-03-07

Treatment-resistant depression (TRD) is a chronic and severe psychiatric illness associated with limited therapeutic options. Deep brain stimulation (DBS) promising therapy for TRD patients. However, its safety efficacy are still unclear. Here we reported the of lateral habenula (LHb) DBS patient who had failed medical, psychological, electroconvulsive, ketamine therapy. The system compatible 3T magnetic resonance imaging along local field potential (LFP) streaming. Two electrodes were...

10.3389/fpsyt.2020.616501 article EN cc-by Frontiers in Psychiatry 2021-01-13

Neural electrode interfaces are essential to the stimulation safety and recording quality of various bioelectronic therapies. The recently proposed hierarchical platinum-iridium (Pt-Ir) electrodes produced by femtosecond lasers have exhibited superior electrochemical performance in vitro, but their vivo is still unclear. In this study, we explored performance, biological response, tissue adhesion Pt-Ir implantation adult rat brains for 1, 8, 16 weeks. Regular smooth were used as a control....

10.1038/s41378-022-00433-8 article EN cc-by Microsystems & Nanoengineering 2022-09-02

Background Developing more effective strategies to prevent relapse remains one of the major challenges treating substance dependence. Previous studies have identified brain abnormalities in abstinent alcoholics. However, whether these persistent deficits abstinence could predict early alcohol use has not been well established. This study aimed identify biomarkers vulnerability by investigating alcohol-dependent patients. Methods Brain imaging and impulsive behavior data were collected from...

10.1371/journal.pone.0196860 article EN cc-by PLoS ONE 2018-05-07

Background Frailty is an independent risk factor for cardiovascular events. It uncertain whether frailty modifies the efficacy of intensive blood pressure (BP) control among participants with type 2 diabetes mellitus(T2DM). Methods The Action to Control Cardiovascular Risk in Diabetes Blood Pressure (ACCORD BP) trial, a two-by-two factorial examined effects systolic BP (&lt;120 vs &lt;140 mm Hg) and glycaemic on events T2DM. We constructed index using Rockwood cumulative deficit approach....

10.1136/heartjnl-2024-324360 article EN Heart 2025-02-06

10.1109/icassp49660.2025.10887967 article EN ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) 2025-03-12

The incidence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) has been increasing world-wide. Since gut-derived bacterial lipopolysaccharides (LPS) can travel via the portal vein to liver and play an important role in producing hepatic pathology, it seemed possible that (1) LPS stimulates cells accumulate lipid, (2) inactivating be preventive. Acyloxyacyl hydrolase (AOAH), eukaryotic lipase inactivates oxidized phospholipids, is produced intestine, liver, other organs. We...

10.7554/elife.100731.2 preprint EN 2025-04-09

The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) has been increasing worldwide. Since gut-derived bacterial lipopolysaccharides (LPS) can travel via the portal vein to and play an important role in producing hepatic pathology, it seemed possible that (1) LPS stimulates cells accumulate lipid, (2) inactivating be preventive. Acyloxyacyl hydrolase (AOAH), eukaryotic lipase inactivates oxidized phospholipids, is produced intestine, liver, other organs. We fed...

10.7554/elife.100731.3 article EN public-domain eLife 2025-04-24

ABSTRACT Ulcerative colitis (UC) is believed to be triggered by a dysregulated inflammatory response the intestinal microbiota. Acyloxyacyl hydrolase (AOAH) unique host lipase that inactivates Gram‐negative bacterial lipopolysaccharides (LPS). After finding AOAH produced in intestine decreases stimulatory LPS levels colon contents, we used dextran sodium sulfate (DSS) model test enzyme's ability prevent mice. We found played protective role decreasing colonic inflammation, tissue injury, and...

10.1096/fj.202500310r article EN The FASEB Journal 2025-04-25

Melanoma, a malignant tumor originating from melanocytes, is the most aggressive and deadly form of skin cancer. Previous studies have revealed that cellular prion protein (PrPC) frequently overexpressed in melanoma, contributing to progression. This study presents first proof‐of‐concept evidence nucleic acid aptamers can be used construct molecular tethering agent regulates PrPC levels by inducing membrane‐bound aggregation for anti‐melanoma therapy. Using screening strategy combining...

10.1002/anie.202425051 article EN Angewandte Chemie International Edition 2025-04-30
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