A5064514159- Neurological disorders and treatments
- Advanced MRI Techniques and Applications
- Neuroscience and Neural Engineering
- Inflammatory Bowel Disease
- EEG and Brain-Computer Interfaces
- Conducting polymers and applications
- Parkinson's Disease Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Advanced Sensor and Energy Harvesting Materials
- Functional Brain Connectivity Studies
- Microscopic Colitis
- Botulinum Toxin and Related Neurological Disorders
- Electrospun Nanofibers in Biomedical Applications
- Hemostasis and retained surgical items
- Advanced Memory and Neural Computing
- Ultrasound and Hyperthermia Applications
- Gastrointestinal motility and disorders
- Modular Robots and Swarm Intelligence
- Drug Solubulity and Delivery Systems
- RNA modifications and cancer
- Advanced Drug Delivery Systems
- Cancer-related molecular mechanisms research
- Electrochemical Analysis and Applications
- Neural dynamics and brain function
- Advanced Materials and Mechanics
Tsinghua University
2016-2025
Beijing Anding Hospital
2013-2024
Capital Medical University
2023-2024
Qingdao University
2013-2024
Qingdao Municipal Hospital
2013-2024
University of Duisburg-Essen
2024
Huazhong University of Science and Technology
2015-2023
Shenzhen University Health Science Center
2023
Union Hospital
2022
Zero to Three
2020
Abstract Recent progress in stretchable forms of inorganic electronic systems has established a route to new classes devices, with particularly unique capabilities functional biointerfaces, because their mechanical and geometrical compatibility human tissues organs. A reliable approach physically chemically protect the components interconnects is indispensable for practical applications. Although recent reports describe various options soft, solid encapsulation, development approaches that...
To investigate the current situation of mental psychology and quality life (QoL) in patients with inflammatory bowel disease (IBD) China, analyze influencing factors.
Objective Current understanding of the neuromodulatory effects deep brain stimulation (DBS) on large‐scale networks remains elusive, largely due to lack techniques that can reveal DBS‐induced activity at whole‐brain level. Using a novel 3T magnetic resonance imaging (MRI)‐compatible stimulator, we investigated subthalamic nucleus (STN) in patients with Parkinson disease. Methods Fourteen received STN‐DBS treatment and participated block‐design functional MRI (fMRI) experiment, wherein...
Deep brain stimulation (DBS) holds great promise in treating various diseases but its chronic therapeutic mechanisms are unclear.To explore the immediate and effects of DBS on oscillations, understand how different sub-bands oscillations may be related to symptom improvement Parkinson's patients.We carried out a longitudinal study examine local field potentials recorded by sensing-enabled neurostimulators subthalamic nuclei patients, using novel block-design paradigm.DBS significantly...
Corneal alkali burns can lead to ulceration, perforation, and even corneal blindness due epithelial defects extensive cell necrosis, resulting in poor healing outcomes. Previous studies have found that chitosan-based situ hydrogel loaded with limbal epithelium stem cells (LESCs) has a certain reparative effect on burns. However, the inconsistent pore sizes of carriers low loading rates resulted suboptimal repair In this study, 4D bioprinting technology was used prepare thermosensitive gel...
Neural electrode interfaces are essential to the stimulation safety and recording quality of various bioelectronic therapies. The recently proposed hierarchical platinum-iridium (Pt-Ir) electrodes produced by femtosecond lasers have exhibited superior electrochemical performance in vitro, but their vivo is still unclear. In this study, we explored performance, biological response, tissue adhesion Pt-Ir implantation adult rat brains for 1, 8, 16 weeks. Regular smooth were used as a control....
Objective: To explore the gender differences in psychological symptoms, sleep quality, and quality of life patients with inflammatory bowel disease (IBD). Methods: A unified questionnaire was developed to collect clinical data on psychology IBD from 42 hospitals 22 provinces China September 2021 May 2022. The general characteristics, different genders were analyzed via a descriptive statistical analysis. multivariate logistic regression analysis conducted, independent influencing factors...
Periostin, an extracellular matrix protein, plays a significant role in adverse cardiac remodeling. However, no report has documented the function of periostin left ventricular remodeling streptozototin (STZ)-induced diabetic rats. The aim present study was to observe expression Wistar rat's myocardium cardiomyopathy (DCM) and effect valsartan on it.Immunohistochemistry, real-time polymerase chain reaction, Western blot analysis were used determine degree location periostin, transforming...
Formation of 3D mesostructures in advanced functional materials is growing interest due to the widespread envisioned applications devices that exploit architectures. Mechanically guided assembly based on compressive buckling 2D precursors represents a promising method, with applicability diverse set geometries and materials, including inorganic semiconductors, metals, polymers, their heterogeneous combinations. This paper introduces ideas extend levels control range layouts are achievable...
The programming of clinical deep brain stimulation (DBS) systems involves numerous combinations parameters, such as stimulus amplitude, pulse width, and frequency. As more complex electrode designs, directional electrodes, are introduced, the traditional trial-and-error approach to manual DBS becomes increasingly impractical. Visualization volume tissue activated (VTA) can assist in selecting parameters by showing direct effects on neural tissue. However, standard method for VTA calculation,...
Abstract Signal loss in blood oxygen level-dependent (BOLD) functional neuroimaging is common and can lead to misinterpretation of findings. Here, we reconstructed compromised fMRI signal using deep machine learning. We trained a model learn principles governing BOLD activity one dataset reconstruct artificially regions an independent dataset, frame by frame. Intriguingly, time series extracted from frames are correlated with the original series, even though do not independently carry any...
Abstract The newly-recognized somato-cognitive action network (SCAN) is posited to be important in movement coordination. Functional disruptions Parkinson’s disease (PD) correspond with complex, non-effector-specific motor symptoms, indicating that SCAN dysfunction may underlie these symptoms. Along the same lines, link multiple neuromodulatory targets used for PD treatment. To investigate role of PD, we leveraged resting-state precision functional mapping, analyzing data from 673...
A new form of deep brain stimulation (DBS) electrode was proposed that made carbon nanotube yarns (CNTYs). Electrode interface properties were examined using cyclic voltammetry (CV) and electrochemical impedance spectrum (EIS). The CNTY exhibited large charge storage capacity (CSC) 12.3 mC/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> which increased to 98.6 after acid treatment, compared with 5.0 Pt-Ir. Impedance both untreated...