- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Transcranial Magnetic Stimulation Studies
- Healthcare Operations and Scheduling Optimization
- Healthcare Policy and Management
- Management, Economics, and Public Policy
- Clostridium difficile and Clostridium perfringens research
- Simulation Techniques and Applications
- Operations Management Techniques
- Neurological disorders and treatments
- Patient Satisfaction in Healthcare
- Inflammatory mediators and NSAID effects
- Neuroscience and Music Perception
- Health Systems, Economic Evaluations, Quality of Life
- Fuzzy Systems and Optimization
- Rough Sets and Fuzzy Logic
- Nosocomial Infections in ICU
- Healthcare Systems and Technology
- Healthcare cost, quality, practices
- Attention Deficit Hyperactivity Disorder
- Colorectal Cancer Screening and Detection
- Multiple Sclerosis Research Studies
- Fractal and DNA sequence analysis
- Diphtheria, Corynebacterium, and Tetanus
Institute of Cognitive Sciences and Technologies
2020-2025
National Research Council
2021-2025
Centro Studi Luca d’Agliano
2024
Istituto di Scienza e Tecnologie dell'Informazione "Alessandro Faedo"
2022
Neuroscience Institute
2022
University of Rome Tor Vergata
2014-2016
Fatebenefratelli Hospital
2009-2013
Sapienza University of Rome
2013
Technical Design (United States)
2013
Six-hundred twenty-one subjects with unilateral asymptomatic severe internal carotid artery (ICA) stenosis were prospectively evaluated a median follow-up of 27 months (min = 6, max 68). Vascular risk profile, plaque characteristic, progression, and common intima-media thickness (IMT) investigated in all patients. Outcome measures occurrence ischemic stroke ipsilateral to ICA vascular death, while myocardial infarction, contralateral strokes, transient attack considered as competing events....
This perspective article addresses the critical and up-to-date problem of task-specific musician’s dystonia (MD) from both theoretical practical perspectives. Theoretically, MD is explored as a result impaired sensorimotor interplay across different brain circuits, supported by most frequently cited scientific evidence—each referenced dozens times in Scopus. Practically, significant issue it occurs over 60 more musicians compared to other professions, underscoring influence individual...
Hospitals are huge and complex systems. However, for many years, the management was commonly focused on improving quality of medical care, while less attention usually devoted to operation management. In recent need containing costs increasing competitiveness along with new policies National Health Service hospital financing forced hospitals necessarily improve their operational efficiency. this paper, we focus a problem arising in health care. particular, deal optimal resource allocation...
The study was conducted to explore the knowledge of pregnant women about influenza, influenza vaccine during pregnancy and attitudes regarding immunization.A questionnaire based on model proposed by Yudin in 2009 translated, adapted administered 309 third trimester between October 1 December 1, 2013 at San Giovanni Calibita Fatebenefratelli hospital Rome (Italy).Most interviewed (68.9%) answered that is highly contagious, 34.6% them believed have same risk complications as non-pregnant...
Introduction The formation and functioning of neural networks hinge critically on the balance between structurally homologous areas in hemispheres. This balance, reflecting their physiological relationship, is fundamental for learning processes. In our study, we explore this functional homology resting state, employing a complexity measure that accounts temporal patterns neurodynamics. Methods We used Normalized Compression Distance (NCD) to assess similarity over time, neurodynamics,...
OPINION article Front. Physiol., 15 December 2020 | https://doi.org/10.3389/fphys.2020.609768
Abstract Sleep crucial for the animal survival is accompanied by huge changes in neuronal electrical activity over time, neurodynamics. Here, drawing on intracranial stereo-electroencephalographic (sEEG) recordings from Montreal Neurological Institute (MNI), we analyzed local neurodynamics waking state at rest and during N2, N3, rapid eye movement (REM) sleep phases. Higuchi fractal dimension (HFD)—a measure of signal complexity—was studied as a feature primary motor (M1), somatosensory...
Objectives: The homology of hemispheric cortical areas plays a crucial role in brain functionality. Here, we extend this concept to the dominant and non-dominant hemi-bodies, investigating relationship two corticospinal tracts (CSTs). evoked responses provide an estimate number in-phase recruitments via their amplitude as suitable indicator neuronal projections’ integrity. An innovative derived from experience somatosensory system is that morphology reflects recruitment pattern whole...
The time course of the neuronal activity in brain network, neurodynamics, reflects structure and functionality generating pools. Here, using intracranial stereo-electroencephalographic (sEEG) recordings public Montreal Neurological Institute (MNI) atlas, we investigated neurodynamics primary motor (M1), somatosensory (S1) auditory (A1) cortices measuring power spectral densities (PSD) Higuchi fractal dimension (HFD) same subject (M1 vs. S1 16 subjects, M1 A1 9, 6). We observed specific...
According to the WHO (World Health Organization), Eye Movement Desensitization and Reprocessing (EMDR) is an elective therapy treat people with post-traumatic stress disorders (PTSD). In line personalization of therapeutic strategies, through this pilot study, we assessed in suffering from effects trauma feasibility, safety, acceptance, efficacy EMDR enriched sound stimulation (by administering neutral sounds synchronized guided bilateral alternating gaze) musical reward (musical listening...
Joy Grifoni1,2Valeria Crispiatico3Anna Castagna4Angelo Quartarone5Rosa Maria Converti4Marina Ramella4Giuseppe Granata6Riccardo Di Iorio6Alfredo Brancucci7Gabriela Bevacqua8Marco Pagani2Teresa L'Abbate1,2Karolina Armonaite1,2Luca Paulon2,3,4,5,6,7,8,9Franca Tecchio2*
OPINION article Front. Neurosci., 14 June 2022Sec. Neuroprosthetics https://doi.org/10.3389/fnins.2022.913410
A new measurement process based upon a well-defined mathematical model was applied to evaluate the quality of human papillomavirus (HPV) vaccination centers in 3 12 Local Health Units (ASLs) within Lazio Region Italy. The aspects considered for evaluation were communicational efficiency, organizational efficiency and comfort.The overall maximum achievable value 86.10%, while HPV scores ASL1, ASL2 ASL3 73.07%, 71.08%, 67.21%, respectively.With this approach it is possible represent...
This proof-of-concept (PoC) study presents a pipeline made by two blocks: 1. the identification of network that generates interictal epileptic activity; and 2. time course electrical activity it generates, called neurodynamics, its functional connectivity to other parts brain. Network is achieved with Functional Source Separation (FSS) algorithm applied electroencephalographic (EEG) recordings, neurodynamics quantified through signal complexity Higuchi Fractal Dimension (HFD), Directed...
Laboratory evidence that inflammatory mechanisms contribute to neuronal injury in Alzheimer disease (AD), along with epidemiological evidence, suggests nonsteroidal anti–inflammatory drugs (NSAIDs) may favorably influence the course of disease. To determine whether nonselective NSAID ibuprofen slows cognitive decline patients mild–to–moderate Alzheimer's (AD). Multicenter, randomized, double–blind, placebo–controlled study, 12–18 months exposure ibuprofen. Seven outpatient centers enrolled...
The neuronal functional connectivity is a complex and non-stationary phenomenon creating dynamic networks synchronization determining the brain states needed to produce tasks. Here, as measure that quantifies between electrical activity of two regions, we used normalized compression distance (NCD), which length compressed file constituted by concatenated signals, files including each single signal. To test NCD sensitivity physiological properties, cortico-muscular synchronization, well-known...