A5101750999- Prenatal Screening and Diagnostics
- Fetal and Pediatric Neurological Disorders
- Cleft Lip and Palate Research
- Neonatal and fetal brain pathology
- Organ Transplantation Techniques and Outcomes
- Assisted Reproductive Technology and Twin Pregnancy
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Congenital Heart Disease Studies
- Cancer, Hypoxia, and Metabolism
- Cardiovascular Health and Risk Factors
- Genetic factors in colorectal cancer
- Glaucoma and retinal disorders
- Reproductive Biology and Fertility
- Pregnancy and preeclampsia studies
- Augmented Reality Applications
- Anatomy and Medical Technology
- Surgical Simulation and Training
- Intracranial Aneurysms: Treatment and Complications
- MicroRNA in disease regulation
- Cardiovascular Issues in Pregnancy
- Craniofacial Disorders and Treatments
- Advanced Glycation End Products research
- Diabetes, Cardiovascular Risks, and Lipoproteins
Xinxiang Central Hospital
2017-2025
Second Affiliated Hospital of Zhejiang University
2025
Renji Hospital
2024-2025
Shanghai Jiao Tong University
2022-2025
Xinxiang Medical University
2024
Suzhou Municipal Hospital
2011-2024
Nanjing Medical University
2016-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024
University of Nottingham Ningbo China
2024
First Affiliated Hospital Zhejiang University
2024
Background. Current prognostic models for liver transplantation (LT) recipients are not applicable long-term survival prediction, especially pediatric living donor LT recipients. In this retrospective study, we aimed to develop and validate a predictive model recipients, the Survival Predictive Model After Pediatric Liver Transplantation (SPPLT) model. Methods. A total of 2964 from Renji Hospital were enrolled randomly assigned training validation cohort by ratio 1:1. Logistic analysis was...
Abstract Bisphenol A (BPA) is a well-known endocrine disruptor compound reported to have prostate toxicity. This study aimed assess the effect of BPA on proliferation dorsolateral (DLP) and expression epithelial–mesenchymal transition (EMT)-related genes in aged rats. Male SD rats were treated with (10.0, 30.0, 90.0 µg/kg i.g., daily) or vehicle (i.g., for 3 months. Treatment resulted increased PCNA, DLP weight epithelial height compared control group ( P < 0.01); such effects more...
Background: Liver transplantation (LT) is the most efficient treatment for pediatric patients with end-stage liver diseases, while bacterial infection leading reason post-transplant mortality. The present study to explore outcomes and risk factors of early (within 1 months) after LT. Methods: In this prospective cohort study, 1316 recipients [median (IQR) age: 9.1 (6.3–28.0) months; male: 48.0%; median follow-up time: 40.6 (29.1–51.4) months] who received LT from September 2018 April 2022...
Abstract Pears rank as the third most produced fruit in China, with widespread cultivation throughout country. Asexual propagation, primarily through grafting onto Pyrus betulifolia rootstocks, is predominant method of cultivation. However, absence an efficient genetic transformation system for P. significantly hinders enhancement efforts pear rootstocks. In this study, TDL39, a genotype, was identified its remarkable regenerative capacity. Leaf strips derived from 60-day-old TDL39 seedlings...
Mobile communication technology is a universal technology. It one of the most advanced technologies in human history due to its rapid development speed, strong penetration and wide application. The application information has brought profound impact on economic growth social transformation. In order test relationship between population change process urban by mobile technology, cluster analysis similarity coefficient are used analyze indicators predict law development. understand changes...
Much evidence demonstrates that mitochondrial dysfunction plays a crucial role in the pathogenesis of vascular complications diabetes. However, signaling pathways through which hyperglycemia leads to endothelial cells are not fully understood. Here, we treated human umbilical vein (HUVECs) with high glucose and examined translocase outer membrane (Tom) 22 on dynamics cellular function. Impaired Tom22 expression protein oxidative phosphorylation (OXPHOS) as well decreased fusion were observed...
Abstract Introduction The potential teratogenic risk of traditional Chinese medicine (TCM) is widespread concern; however, related evidence largely absent in humans. This study aimed to compare the prevalence congenital malformations between pregnant women with and without TCM exposure. Material methods was a multicenter prospective cohort 17 713 who participated survey on periconceptional Primary outcome diagnosed from conducted day 42 after delivery. Results A total 16 751 273 were...
To study the validity of an artificial intelligence (AI) model for measuring fetal facial profile markers, and to evaluate clinical value AI identifying abnormalities during first trimester.This retrospective used two-dimensional mid-sagittal images taken singleton pregnancies at 11-13+ 6 weeks gestation. We measured including inferior angle (IFA), maxilla-nasion-mandible (MNM) angle, facial-maxillary (FMA), frontal space (FS) distance, line (PL) distance using manual measurements. Semantic...
Abstract Objective To evaluate the clinical value of three‐dimensional ultrasound (3D‐US) with reformatting technique in diagnosis fetal cleft lip/palate (CL/P), especially those involving secondary palate. Methods A total 113 fetuses suspected lip (CL) on two‐dimensional (2D‐US) were further evaluated by 2D‐US and 3D‐US technique, order to clarify type oral cleft. Lesions classified as (CL), alveolus (CLA), palate (CLP) (including primary palate). All followed until birth or termination...
General practitioners are trained to care for patients with a high level of responsibility and professional competency. However, there few reports on the physical mental health status general (GPs) in China, particularly regarding help seeking self-treatment. The primary aims this study were explore GPs' expectations their own family doctors reflection role positioning, objective factors that hinder system doctors.
To explore the clinical significance of sonographic (US) diagnosis fetal arachnoid cysts and to evaluate their prognosis.Sixty fetuses deemed have by prenatal US were included in this study. Data from serial US, and/or postnatal MRI, or post-mortem examinations retrospectively analyzed. For live births, developmental quotient scores determined using Gesell Developmental Scale.Thirty diagnosed during second trimester another 30 third trimester. Fifty-one lesions located supratentorial...
To establish reference ranges of fetal intracranial markers during the first trimester and develop novel artificial intelligence (AI) model to measure key automatically.
Abstract Photodynamic therapy is a new technology for disease diagnosis and treatment in modern medical clinics. The main advantages of photodynamic are low toxicity side effects, wide range applications, no drug resistance, obvious trauma the process. However, to achieve effective therapy, photosensitizer carriers need be constructed, which can selectively deliver photosensitizers into tumor tissues. In this work, photoactivatable antibody–Chlorin e6 conjugate with dual-function target...
Substance P (SP) is a candidate mediator along the brain–skin axis and can mimic effects of stress to regulate melanogenesis. Previously, we others have found that regulation SP for pigmentary function was mediated by neurokinin 1 receptor (NK1R). Emerging evidence has accumulated psychologic induce dysfunction in cutaneous serotonin 5-hydroxytryptamine (5-HT)-5-HT1A/1B system, thereby resulting skin hypopigmentation. Moreover, NK1R 5-HTR (except 5-HT3) belong GPCR. The present study aimed...
To investigate the protective effect of glucagon-like peptide-1 (GLP-1) against cell damage induced by high glucose. Human umbilical vein endothelial cells (HUVECs) were divided into control group (5.5 mmol/L) and glucose groups (19, 33, or 47 mmol/L), which cultured with different concentrations for 48 hours, respectively. Cell viability was measured MTT assay. Levels intracellular reactive oxygen species (ROS) monitored flow cytometry apoptotic death staining Annexin V-FITC propidium...
Abstract Background To establish reference ranges of fetal facial profile markers and study their correlations with crown-rump length (CRL) during the first trimester (11 ~ 13 + 6 weeks’ gestation) in a Chinese population. Methods Ultrasonographic images measuring nuchal translucency (NT) were retrospectively selected randomly normal fetuses whose parents both Chinese. The included inferior angle (IFA), maxilla-nasion-mandible (MNM) angle, maxillary (FMA) line (PL) distance. These measured...