A5103138537- Advanced biosensing and bioanalysis techniques
- Vitamin D Research Studies
- Advanced Glycation End Products research
- Biosensors and Analytical Detection
- Adipokines, Inflammation, and Metabolic Diseases
- Nutritional Studies and Diet
- Epigenetics and DNA Methylation
- Cardiovascular Function and Risk Factors
- Advanced Nanomaterials in Catalysis
- Food Quality and Safety Studies
- Diet and metabolism studies
- Microbial Metabolism and Applications
- Sustainable Industrial Ecology
- Liver Disease Diagnosis and Treatment
- Vitamin C and Antioxidants Research
- Chemistry and Chemical Engineering
- Metabolomics and Mass Spectrometry Studies
- Pharmacological Effects of Natural Compounds
- Gout, Hyperuricemia, Uric Acid
- Metabolism, Diabetes, and Cancer
- Nutrition, Genetics, and Disease
- Obesity, Physical Activity, Diet
- Pancreatic function and diabetes
- Phagocytosis and Immune Regulation
- Alcohol Consumption and Health Effects
Shenzhen Second People's Hospital
2025
Shandong University
2009-2024
Qilu Hospital of Shandong University
2013-2024
Shanghai Clinical Research Center
2024
Zhengzhou University
2014-2024
Shanghai East Hospital
2015-2024
Qilu University of Technology
2021-2024
Xinjiang Normal University
2023-2024
University of Science and Technology of China
2024
China Medical University
2024
Ecosystem services (ESs) have been widely used in the management and protection of regional ecosystems. Among numerous influencing factors, climate vegetation are important factors affecting ESs. Nevertheless, unraveling intricate non-linear relationship between ESs fluctuations fractional cover (FVC) remains an elusive task, particularly within dynamic context mountainous terrains. Therefore, Qinling Mountains (QL) was selected as study area, four major (habitat quality, water yield, carbon...
Affective disorders, especially depressive symptoms, bring such a burden to mortality and morbidity that they are associated with physical psychological health quality of life. Nuts, foodstuff rich in multiple micronutrients, macronutrients, other useful components, were considered be protector against symptoms. Here, we conducted an analysis examine the relationship between nut consumption symptoms.The study performed cross-sectional whether is related symptoms among 13,626 inhabitants...
BACKGROUND: Adlay (Coix lacryma-jobi L. subsp. ma-yuen (Romanet) T. Koyama (family Poaceae)) seed has been used as a dietary supplement for its therapeutic effects thousands of years. This study was designed to investigate the adlay oil, obtained by supercritical CO2 extraction, on blood lipids and antioxidant capacity in hyperlipidemic rats. RESULTS: oil could reduce abdominal fat tissue low-density lipoprotein concentration, increase total also significantly decreased malondialdehyde...
The prevalence of type 2 diabetes mellitus (T2DM) has increased considerably in recent years, highlighting the importance developing new therapeutic strategies. Insulin-resistance and gradual dysfunction pancreatic islets are mainstay progression T2DM. Therefore, preserving function pancreas may lead to prospective approaches. Our previous studies suggested that grape seed procyanidin B2 (GSPB2), a natural polyphenol product, exhibited protective effects on diabetic vasculopathy. However,...
Abstract Background Diabetic sarcopenia is a disease‐related skeletal muscle disorder that causes progressive symptoms. The complete understanding of its pathogenesis yet to be unravelled, which makes it difficult develop effective therapeutic strategies. This study investigates how MFG‐E8 affects mitophagy and the protective role D‐pinitol (DP) in diabetic sarcopenia. Methods In vivo, streptozotocin‐induced SAM‐R1 (STZ‐R1) SAM‐P8 (STZ‐P8) mice (16‐week‐old) were used, STZ‐P8 administrated...
Patients with diabetes often develop hypertension and atherosclerosis leading to cardiovascular disease. However, some diabetic patients heart failure without coronary artery disease, a process termed cardiomyopathy. Phlorizin has been reported be effective as an antioxidant in treating mellitus, but little is known about its cardioprotective effects on In this study, we investigated the role of phlorizin preventing cardiomyopathy db/db mice. We found that significantly decreased body weight...
Background Atherosclerosis is one of the major complications type 2 diabetic patients (T2DM), leading to morbidity and mortality. Grape seed procyanidin B2 (GSPB2) has demonstrated protective effect against atherosclerosis, which believed be, at least in part, a result its antioxidative effects. The aim this study identify target protein GSPB2 responsible for atherosclerosis with DM. Methods Results (30 mg/kg body weight/day) were administrated db/db mice 10 weeks. Proteomics aorta extracts...
Abstract Enhanced muscle strength is often related to improved insulin sensitivity and secretion, control of lipid metabolism, increased secretion myokines. These factors have emerged as important mechanisms involved in the development progression nonalcoholic fatty liver disease (NAFLD), implying that may be a useful predictor for NAFLD. We aimed assess relationship between grip (GS) NAFLD large-scale adult population. GS was assessed using an electronic hand-grip dynamometer, diagnosed by...
Diabetes is commonly associated with liver lipid metabolism disorders. AMP-activated protein kinase (AMPK) has a key role in regulating metabolism. Grape seed procyanidin B2 (GSPB2), natural polyphenol polymer, ameliorates mitochondrial dysfunction and inhibits oxidative stress or apoptosis via AMPK pathways. In the present study, hypothesis that GSPB2 treatment may ameliorate metabolic disorders by activating downstream pathways was tested diabetic mice. Db/m mice were used as controls,...
The work is for the purpose of studying influence drying temperature and ultrasound on kinetics, antioxidant enzymes, germination performance pea seeds. experiments were performed at air 30, 35, 40°C without with three ultrasonic levels 28 kHz + 60 W, 100 40 W. enzymes including superoxide dismutase (SOD), peroxidase (POD), catalase (CAT) toxic substances such as malondialdehyde (MDA) dried seeds determined, percentage (GP), index (GI), mean time (MGT) measured. result showed that high...
Osteoarthritis (OA) is a chronic and complicated degenerative disease for which there currently no effective treatment. Isoorientin (ISO) natural plant extract that has antioxidant activity could be used to treat OA. However, due lack of research, it not been widely used. In this study, we investigated the protective effects molecular mechanisms ISO on H2O2-induced chondrocytes, cell model Based RNA-seq bioinformatics, discovered significantly increased chondrocytes induced by H2O2, was...