A5030970487- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Respiratory Support and Mechanisms
- Acute Kidney Injury Research
- Cardiac Arrest and Resuscitation
- Neonatal Respiratory Health Research
- Hip and Femur Fractures
- Airway Management and Intubation Techniques
- Congenital Diaphragmatic Hernia Studies
- Nutrition and Health in Aging
- Kawasaki Disease and Coronary Complications
- Dialysis and Renal Disease Management
- Clinical Nutrition and Gastroenterology
- Intestinal Malrotation and Obstruction Disorders
- Pericarditis and Cardiac Tamponade
- Digestive system and related health
- Chemotherapy-induced organ toxicity mitigation
- Trauma and Emergency Care Studies
- Autoimmune and Inflammatory Disorders Research
- Acne and Rosacea Treatments and Effects
- Nephrotoxicity and Medicinal Plants
- Burn Injury Management and Outcomes
- Anomaly Detection Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Electrolyte and hormonal disorders
Koç University
2021-2025
Hacettepe University
2014-2022
Hacettepe University Hospital
2015-2019
Mersin Üniversitesi
2019
Objective: Intravenous immunoglobulin and plasma exchange are proven treatments for Guillain-Barré syndrome. Despite these treatments, the prognosis severe syndrome is still not satisfactory. This article seeks a logical timing exchange–intravenous synergy, which may improve outcome in requiring mechanical ventilation. Study Design: study an open-label study. Nine pediatric patients ventilation were treated with novel treatment strategy named as “zipper method.” In this method, following...
The most common medical sequelae after earthquakes are crush injuries and syndromes that require urgent well-organized care, which further complicates the approach in face of overstretched resources. 2023 Kahramanmaraş earthquake, with a magnitude 7.7, was one largest disasters Türkiye, affecting 11 cities population about 13.5 million people claiming more than 50,000 deaths. Approximately 4.6 pediatric patients were affected, over 500 children undergoing amputations. overwhelming number...
Abstract Background: This study investigated the prevalence of malnutrition, time to achieve caloric goals, and nutritional risk factors after surgery for CHD in a cardiac ICU. Method: retrospective included patients with (1 month-18 years old) undergoing open-heart (2021–2022). We recorded status, body mass index-for-age z-score, weight-for-length/height cardiopulmonary bypass aortic cross-clamp time, Paediatric Risk Mortality-3 score, Logistic Organ Dysfunction-2 vasoactive inotropic total...
Abstract Background Acute kidney injury ( AKI ) is associated with an increased risk of mortality, especially in pediatric intensive care units. The aim this study was to determine the factors children undergoing cardiac surgery for congenital heart disease and compare two different classification systems: risk–injury–failure–loss–end‐stage renal pRIFLE Kidney Injury Network AKIN ). Methods We retrospectively analyzed 145 patients who were between 1 month 18 years years, treated at a...
Background: Continuous renal replacement therapies (CRRTs) either as continuous venovenous hemofiltration (CVVH) or hemodiafiltration (CVVHD) are used frequently in critically ill children. Many clinical variables and technical issues known to affect the result. The factors that could be modified increase survival of sought. As a contribution, we present data on 104 patients who underwent CRRT within 7-year period. Materials Method: A total admitted between 2009 2016 were included study....
Aim Although early enteral nutrition (EN) is strongly associated with lower mortality in critically ill children, there no consensus on the definition of EN. The aim this study was to evaluate our current practice supplying EN and identify factors that affect both initiation feeding within 24 h after paediatric intensive care unit (PICU) admission adequate supply first 48 PICU children. Methods We conducted a prospective, multicentre, observational nine PICUs Turkey. Any kind tube commenced...
Post-extubation respiratory failure is associated with a poor prognosis due to increased ventilator-associated pneumonia, and longer length of stay in the ICU hospital. In this study, we aimed evaluate efficacy high-flow nasal cannula (HFNC) noninvasive mechanical ventilation (NIMV) on extubation success children. A total 48 patients, aged between 1 month 18 years, who were weaned either NIMV or HFNC included. Patients had tracheostomy not underwent unplanned excluded. Age, gender,...
Continuous venovenous hemofiltration or hemodiafiltration is used frequently in pediatric patients, but experience of continuous renal replacement therapy (CRRT) application on extracorporeal membrane oxygenation (ECMO) circuit still limited. Among several methods for applying CRRT ECMO we aim to share our inclusion a device the which believe easier and safer apply.The data were collected demographics, outcomes, details treatment patients who had CRRT. During study period 3 years, venous...
Congenital hypothyroidism (CH) may present with nonspecific signs and symptoms, though, majority of infants can be asymptomatic. Therefore, understimation delay in diagnosis result severe complications. A 5-month-old female admitted to our clinic the history repeated surgical operations due congenital aganglionic megacolon. Investigations performed revealed (primary) thyroid agenesis. Histopathologic evaluation previously resected colon sample normal ganglionic cell included colon. During...
Severe metabolic crises in children with inborn errors of metabolism can result mortality or severe morbidities where continuous renal replacement therapy (CRRT) be lifesaving . Clinical data, the pediatric risk (PRISM) scores calculated first 24 hours, and logistic organ dysfunction (PELOD) last hours before CRRT, were studied Overall, CRRT was successful restoring balance 72% patients. PELOD lower survivors ( p = 0.02). Despite numerous comorbid factors, used effectively management crises....
Background: This study aims to investigate whether thiol/disulfide homeostasis parameters measurements could be used as a new biomarker predict the pre- and post-cardiopulmonary bypass oxidative status of pediatric patients undergoing congenital heart surgery. Methods: A total 40 children with disease (17 males, 23 females; mean age: 39.6±40.0 months; range, 2 216 months) who underwent open-heart surgery were included. The control group consisted age- sex-matched healthy (18 22 42.8±46.6 12...
Abstract Background: The best transfusion approach for CHD surgery is controversial. Studies suggest two strategies: liberal (haemoglobin ≤ 9.5 g/dL) and restrictive (waiting until haemoglobin 7.0 g/dL if the patient stable). Here we compare in post-operative patients a cardiac intensive care unit. Methods: Retrospective analysis was conducted on who received (2019–2021, n=53) (2021–2022, n=43). Results: groups were similar terms of age, gender, Paediatric Risk Mortality-3 score, Logistic...
Background: In this study, we aimed to evaluate the outcomes of our on-table extubation strategy in patients with congenital heart disease. Methods: Between April 2021 and November 2022, a total 114 pediatric (58 males, 56 females; median age: 25.3 months; range, 57.5 4.4 months) who were operated for diseases retrospectively analyzed. The evaluated according Society Thoracic Surgeons-European Association Cardio-Thoracic Surgery (STS-EACTS) scoring system. Perioperative patient data analyzed...
Background and aims: Vinblastine are used for the treatment of leukemias, lymphomas, certain solid tumours. cause bone marrow suppression, neurotoxicity, mucositis, CNS disorders, syndrome inappropriate antidiuretic hormone (SIADH). Aims: We report a fourteen year-old girl who was diagnosed with myelofibramatosis, received accidentally massive overdose vinblastine. She succesfully managed by plasma-exchange other supportive therapy. Methods: A 14-year-old receiving weekly...
Vitamin D-deficient rickets is still an important and common health problem in developing countries. Since calcium essential ion for cardiac muscle contraction, deficiency caused by can cause secondary dilated cardiomyopathy. This situation be exacerbated coexisting hypomagnesemia. Here, we report a case of cardiomyopathy due to hypocalcemia induced vitamin accompanying primary hypomagnesemia infant whose was successfully treated replacement calcium, D, magnesium. In addition genetic causes,...
Background and aims: Cardiac tamponade is a rare complication of systemic lupus erythematosus (SLE) especially in the pediatric population as an initial presentation. We report thirteen years old young girl who was admitted to emergency department with severe chest pain, generalized edema, because cardiac plevral effusion, later diagnosed SLE. Aims: SLE should keep mind differencial diagnosis tamponade. Methods: She succesfully treated pulse methylprednisone cyclophosphamide medication...
<h3>Background</h3> Natural killer (NK) cell lymphoma is a rare and aggressive neoplasm characterised by angioinvasion or angiodestruction. The aim of this report to describe patient with an poor prognosis which might be interest for the clinicians. <h3>Case presentation</h3> We herein case 14-year-old girl suffering from cough back pain one week. Computerised tomography showed bilateral pleural effusions mediastinal axillary lymph nodes. specimen effusion transudate character no...
Background and aims: Cisplatin which is an effective anti-tumour agent, used to treat a wide variety of tumours. The most serious complication cisplatin toxicity nephrotoxicity, may result in renal failure. Aims: We report baby who was diagnosed with pons glioma, received lethal dose as accidental subtitution for carboplatin. He succesfully managed by plasma exchange, amifostine sodium thiosulfate therapy. Methods: A fourteen month glioma. three cycle carboplatin etoposid chemotherapy. On...
Background and aims: Acute kidney injury (AKI) is common after cardiac surgery, occuring in 5%-33%, associated mortality varies between 20%-79%. Aims: Make a comparison two different classification system pediatric Risk, Injury, Failure, Loss of function End-stage disease (pRIFLE) Kidney Injury Network (AKIN) to evaluate the prevalence association AKI. Methods: A retrospective analysis patient undergoing congenital heart surgery whose age 1 month 18 years that were operated January...