- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Bacterial Infections and Vaccines
- Streptococcal Infections and Treatments
- Gut microbiota and health
- Respiratory viral infections research
- Erythrocyte Function and Pathophysiology
- Tracheal and airway disorders
- Blood groups and transfusion
- Neonatal and Maternal Infections
- COVID-19 Clinical Research Studies
- Diabetes and associated disorders
- Epilepsy research and treatment
- Clinical Nutrition and Gastroenterology
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Clostridium difficile and Clostridium perfringens research
- Central Venous Catheters and Hemodialysis
- Inflammation biomarkers and pathways
- Environmental and Sediment Control
- Respiratory and Cough-Related Research
- Antibiotic Resistance in Bacteria
- Kawasaki Disease and Coronary Complications
- Migration, Health and Trauma
Eskişehir Osmangazi University
2016-2025
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2016-2024
CARE USA
2022-2024
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi
2020-2021
Eskişehir City Hospital
2021
Ümraniye Eğitim ve Araştırma Hastanesi
2018
Intensive Care Society
2018
Background: The inability to ensure adequate nutrition for patients, and failure provide calorie protein intake, result in malnutrition, leading increased morbidity mortality. present study assesses the two approaches enteral nutrition—intermittent continuous feeding—in critically ill pediatric patients Türkiye determine superiority of one method over other. Methods: Included this multicenter prospective were receiving via a tube who followed up 3-month period. Anthropometric data, signs...
Ivabradine has been shown to be safe and effective in treating congenital postoperative junctional ectopic tachycardia children; however, recent years, case reports have suggested that it may also used treat automaticity-related atrial focal tachycardia. Here, we discussed a which ivabradine induce sinus rhythm 38-day-old baby who had resistant supraventricular investigated potential accessory pathway-related
There have been some significant changes regarding healthcare utilization during the COVID-19 pandemic. Majority of reports about impact pandemic on diabetes care are from first wave We aim to evaluate potential effects severity diabetic ketoacidosis (DKA) and new onset Type 1 presenting with DKA, also children DKA acute infection. This is a retrospective multi-center study among 997 adolescents type who were admitted 27 pediatric intensive units in Turkey between year pre-pandemic year. The...
Aim Although early enteral nutrition (EN) is strongly associated with lower mortality in critically ill children, there no consensus on the definition of EN. The aim this study was to evaluate our current practice supplying EN and identify factors that affect both initiation feeding within 24 h after paediatric intensive care unit (PICU) admission adequate supply first 48 PICU children. Methods We conducted a prospective, multicentre, observational nine PICUs Turkey. Any kind tube commenced...
Hemophagocytic lymphohystiocytosis (HLH) is characterized by fever, splenomegaly, pancytopenia, and elevated levels of triglycerides ferritin. These signs symptoms are common to other metabolic diseases.A 5-month-old female infant, who presented with respiratory distress, massive hepatomegaly, bicytopenia, was diagnosed as having HLH chemotherapy initiated. The patient negative for familial gene mutations. Respiratory distress laboratory findings improved rapidly after starting chemotherapy....
Background. Respiratory tract infections are among the most important causes of mortality and morbidity in children worldwide. The COVID-19 pandemic has affected distribution seasonal respiratory viruses as all areas life. In this study, we have aimed to evaluate changes rates with onset pandemic. Methods. This study included patients who were admitted Pediatrics Clinic Eskisehir Osmangazi University Faculty Medicine Hospital between December 2018 February 2022 whom pathogens detected from...
Background Much of the knowledge regarding pediatric healthcare-associated infections is based on studies conducted in adults. Here, we investigated clinical risk factors and etiologic organisms, focusing antibiotic antifungal resistance patients with nosocomial bloodstream (nBSIs) intensive care units (PICUs). Methods A retrospective evaluation was nBSI PICUs a tertiary referral hospital. Results total 69 episodes 65 were observed during study period. Of these, 40 (57.97%) caused by...
Endocan is an endotelial cell specific molecule; previous studies have shown that serum endocan levels increased in cancer and sepsis are also related to the severity of sepsis. There no clinical study about children with febrile neutropenia. The aim this was evaluate pediatric leukemia patients neutropenia (n = 33) compare them without fever healthy 24). median level first group (children neutropenia) statistically significantly higher compared leukemic control (p < 0.01 for both). No...
Introduction Although there are studies about sepsis treatment in different age groups, data on immunoglobulin-M (IgM)-enriched intravenous immunoglobulin use pediatric intensive care units (PICUs) limited. The aim of this study was to evaluate the clinical features and prognoses children receiving IgM-enriched treat sepsis, septic shock, multi-organ failure.Method We extracted from medical records 254 who received infusion (104 for 3 days, 150 5 days) addition standard between 2010...
Abstract Background: Microbiota composition may play a role in the development, prognosis, or post-infection of COVID-19. There are studies evaluating microbiota at time diagnosis and during course COVID-19, especially adults, while children limited no study available with multisystem inflammatory syndrome (MIS-C). This was planned to evaluate changes intestinal diagnosed MIS-C acute COVID-19 infection compare them healthy children. Methods: In this prospective multicenter study, 25 MIS-C,...
Heterozygous intragenic mutations of the hepatocyte nuclear factor 1 homeobox b gene (HNF1B) located on chromosome 17 and microdeletion 17q12 region (17q12MD) leads to complete loss this gene, which causes renal cystic disease, diabetes mellitus (MODY5), hypomagnesemia, hyperuricemia, liver enzyme abnormalities, genital tract abnormalities exocrine pancreatic insufficiency. In addition, patients with 17q12MD also have facial dysmorphism, neuro-developmental neuropsychiatric disorders.A...
The development of AKI (acute kidney injury) in critically ill patients pediatric intensive care units (PICUs) is one the most important factors affecting mortality. There are scoring modalities used to predict mortality PICUs. We compared AKIN (Acute Kidney Injury Network) and pRIFLE (pediatric risk, injury, failure, loss, end stage) classifications PICU this study.A total 716 children, whose serum creatinine levels were within normal limits at time admission between January 2018 December...
Microbiota composition might play a role in the pathophysiology and course of sepsis, understanding its dynamics is clinical interest. Invasive meningococcal disease (IMD) an important cause community-acquired serious infection, there no information regarding microbiota children with meningococcemia. In this study, we aimed to evaluate intestinal nasopharyngeal IMD. Materials Methods: prospective, multi-center 10 meningococcemia age-matched healthy controls were included. Nasopharyngeal...
Autoimmune hemolytic anemia is a picture of hemolysis which caused by autoantibodies against red blood cell surface antigens.It classified as primary, secondary or warm and cold autoimmune according to the temperature at antibodies react.It usually an acute self-limiting condition.Here, we present three-year-old male patient who presented with malaise, paleness, dark-colored urine.His hemoglobin level was 5.8 g/dL, increased indirect bilirubin lactate dehydrogenase levels decreased...
Abstract The increase of available synthetic cannabinoids poses an emerging public health threat worldwide. Synthetic cannabinoid use has been mainly reported in adolescent cases pediatric practices; there are few involving infants affected by unintentional use. In this case report, we present the youngest age bonzai exposure literature, discussing a 3-month-old child to parents' home environment. Because like might be encountered, emergency teams should aware condition and protection...
Molybdenum cofactor deficiency (MOCOD) is a severe inborn error of metabolism. It characterized by neonatal presentation intractable seizures, feeding difficulties, developmental delay, microcephaly with brain atrophy and coarse facial features. Movement disorders have been rarely reported as presenting complaint MOCOD. We report previously healthy 10 months old boy acute onset status dystonicus. A novel homozygote IVS1-1G>A (c.251-1G>A) mutation was determined he diagnosed MOCOD must be...
Abstract Objective Acute respiratory tract infections are one of the leading causes morbidity and mortality in children. Although human bocavirus (HBoV) not as common other seasonal viruses, children who infected with HBoV more likely to suffer from a variety conditions, including cold, acute otitis media, asthma exacerbations, bronchiolitis pneumonia, some affected require pediatric intensive care unit stay. Here, we aimed evaluate cases presenting severe symptoms during coronavirus disease...
Introduction: Lower respiratory tract infections are the leading cause of morbidity and mortality in children worldwide. It is crucial to promptly conduct diagnostic investigations order determine microbiological pneumonia, since this necessary ensure appropriate delivery antibiotic therapy each individual patient. We evaluated results a rapid molecular pneumonia panel with LRTI pediatric intensive care unit (PICU). Patients Methods: Rapid (BioFire®, FilmArray Pneumonia Panel plus; FA-PP)...
To the Editors: Lung abscesses are characterized by presence of purulent material within thick-walled cavities, which develop as a consequence acute loss lung parenchyma.1 In pediatric patients, occur without any identifiable predisposing factors primary or secondary, arise in underlying factors.1,2 A 7-year-old girl diagnosed with cerebral palsy, who had been receiving mechanical ventilator support at home, arrived hospital chief complaint worsening respiratory distress persisting for 6...
Özgün Araştırma
ÖzGiriş: İnvaziv bakteriyel enfeksiyonlar, tüm dünyada en yaygın mortalite ve morbidite nedenleri arasında yer almaktadır.Bu çalışma ile COVID-19 pandemi önlemlerinin gevşetilmesi birlikte görülen
ÖzSon yıllarda, albicans dışı Candida türlerinin neden olduğu kandidemi sıklığında belirgin bir artış bildirilmiştir.Candida utilis,
ÖzGiriş: Santral sinir sistemi (SSS) enfeksiyonları hızlı ilerlemesi ve mortaliteye ya da ciddi kalıcı sekellere yol açması nedeniyle tanı gerektirir.Bu çalışmada SSS enfeksiyonu şüphesi FilmArray Menenjit Ensefalit Paneli (