Lawrence B. Marks

ORCID: 0000-0001-8832-3303
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Lung Cancer Diagnosis and Treatment
  • Effects of Radiation Exposure
  • Breast Cancer Treatment Studies
  • Radiation Dose and Imaging
  • Medical Imaging Techniques and Applications
  • Advances in Oncology and Radiotherapy
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Cancer Studies
  • Lung Cancer Treatments and Mutations
  • Ultrasound and Hyperthermia Applications
  • Radiation Therapy and Dosimetry
  • Management of metastatic bone disease
  • Brain Metastases and Treatment
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Glioma Diagnosis and Treatment
  • Breast Lesions and Carcinomas
  • Cardiac Imaging and Diagnostics
  • Cancer Treatment and Pharmacology
  • Patient Safety and Medication Errors
  • Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Breast Implant and Reconstruction
  • Radiology practices and education
  • Childhood Cancer Survivors' Quality of Life

University of North Carolina at Chapel Hill
2016-2025

West Virginia University Institute of Technology
2025

UNC Lineberger Comprehensive Cancer Center
2011-2024

Stanford Blood Center
2023

Stanford University
2002-2023

University of North Carolina Hospitals
2010-2021

Northwell Health
2020

University of North Carolina Health Care
2009-2017

Radiation Oncology Associates
1995-2017

Duke University Hospital
1992-2017

PURPOSE: Weight gain is a common problem among breast cancer patients who receive adjuvant chemotherapy (CT). We undertook study to determine the causes of this energy imbalance. PATIENTS AND METHODS: Factors related balance were assessed at baseline (within 3 weeks diagnosis) and throughout 1 year postdiagnosis 53 premenopausal women with operable carcinoma. Thirty-six received CT 17 only localized treatment (LT). Measures included body composition (dual x-ray absorptiometry), resting...

10.1200/jco.2001.19.9.2381 article EN Journal of Clinical Oncology 2001-05-01

PURPOSE We studied high-dose cyclophosphamide, cisplatin, and carmustine (CPA/cDDP/BCNU) with autologous bone marrow support (ABMS) as consolidation after standard-dose adjuvant chemotherapy treatment of primary breast cancer involving 10 or more axillary lymph nodes. PATIENTS AND METHODS One hundred two women stage IIA, IIB, IIIA, IIIB nodes at surgery were registered; 85 eligible, treated, assessable. Patients treated four cycles doxorubicin, fluorouracil (CAF), followed by CPA/cDDP/BCNU...

10.1200/jco.1993.11.6.1132 article EN Journal of Clinical Oncology 1993-06-01

Purpose The significance of radiotherapy (RT) -associated cardiac injury for stage III non-small-cell lung cancer (NSCLC) is unclear, but higher heart doses were associated with worse overall survival in the Radiation Therapy Oncology Group (RTOG) 0617 study. We assessed impact dose patients treated at our institution on several prospective dose-escalation trials. Patients and Methods From 1996 to 2009, 127 NSCLC (Eastern Cooperative performance status, 0 1) received dose-escalated RT 70 90...

10.1200/jco.2016.70.0229 article EN Journal of Clinical Oncology 2017-02-23

Treatment planning tools that use biologically related models for plan optimization and/or evaluation are being introduced clinical use. A variety of dose-response and quantities along with a series organ-specific model parameters included in these tools. However, due to various limitations, such as the limitations available parameters, incomplete understanding dose responses, inadequate data, based treatment system (BBTPS) represents paradigm shift can be potentially dangerous. There will...

10.1118/1.3685447 article EN Medical Physics 2012-02-21
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