A5101690512- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer, Lipids, and Metabolism
- Antioxidant Activity and Oxidative Stress
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cholesterol and Lipid Metabolism
- Lipid metabolism and disorders
- Fatty Acid Research and Health
- Adipose Tissue and Metabolism
- Cardiovascular Health and Disease Prevention
- Underwater Vehicles and Communication Systems
- Nutritional Studies and Diet
- Glaucoma and retinal disorders
- Folate and B Vitamins Research
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Retinal Development and Disorders
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Atherosclerosis and Cardiovascular Diseases
- Metabolism and Genetic Disorders
- Free Radicals and Antioxidants
- Vitamin C and Antioxidants Research
Jikei University School of Medicine
2015-2025
Jikei University Kashiwa hospital
2016-2025
Nippon Medical School
2024
Hijiyama University
2010-2021
Tokyo National Hospital
2021
Tokyo Metropolitan Neurological Hospital
2007-2015
Hôpital Sainte-Marguerite
2014
Kure Medical Center
2008-2009
Fujitsu (Japan)
2009
National Hospital Organization
2008
Revisions 1. CQs and Systematic Review (SR)In the subsections on dyslipidemia in assessment of risk factors, absolute ASCVD, lipid management targets as well drug therapy diet improving lifestyle habits, we created performed an SR based MINDS method.For our SR, essentially chose literature published before end 2015. Calculation Absolute RiskFollowing 2012 version, has been using calculation described this set guidelines.The NIPPON DATA80, which was used to calculate result baseline surveys...
Glaucoma, a progressive optic neuropathy due to retinal ganglion cell (RGC) degeneration, is one of the leading causes irreversible blindness. Although glaucoma often associated with elevated intraocular pressure (IOP), IOP elevation not detected in significant subset glaucomas, such as normal tension (NTG). Moreover, some patients, reduction does prevent progression disease. Thus, understanding IOP-independent mechanisms RGC loss important. Here, we show that mice deficient glutamate...
8CQ: Is comprehensive risk assessment using prediction models for the primary prevention of CVD helpful in reducing mortality?
Background— Recurrence of atrial fibrillation (AF) after successful pulmonary vein isolation (PVI) occurs mainly due to the reconnection once isolated PV. Although provocation and elimination early (EPVR) soon PVI has been widely performed improve outcome, AF recurrence subsequent PV reconnections still occurs. In this study, we repeatedly provoked eliminated EPVR determine appropriate procedural end point. Methods Results— Seventy-five patients with paroxysmal underwent PVI. was by both...
To assess the effects of spermidine on severity experimental autoimmune encephalomyelitis (EAE), an animal model multiple sclerosis (MS), with a focus optic neuritis often associated MS and EAE.Myelin oligodendrocyte glycoprotein-induced EAE mice were administered or without at 30 mM in drinking water for 25 days. Clinical signs scored daily, visual functions measured by multifocal electroretinograms. Histopathology analysis spinal cord nerve was performed after killed day 25. Hydrogen...
We have developed a high-performance liquid chromatography (HPLC) method for measurement of cholesterol in the major classes serum lipoproteins, i.e., HDL, LDL, IDL, VLDL, and chylomicrons. Lipoproteins were separated on column containing diethylaminoethyl-ligand nonporous polymer-based gel by elution with step gradient sodium perchlorate concentration, detected post-column reaction reagent esterase oxidase. The within-day assay between-day coefficients variation concentration lipoproteins...
<h3>Background</h3> Although several clinical variables are associated with the recurrence of atrial fibrillation (AF) following catheter ablation, influence renal function remains to be determined. <h3>Objective</h3> To evaluate association outcome paroxysmal AF ablation. <h3>Methods</h3> 224 patients underwent ablation for AF. The relationship between pre-procedural valuables and outcomes was evaluated. <h3>Results</h3> Over course 37.4±24.4 months follow-up procedures (mean number...
To examine the effects of supervised aerobic exercise training on serum adiponectin and lipids, including triglyceride (TG)-rich lipoproteins, in moderate dyslipidemic subjects.Twenty-five patients [mean body mass index (BMI)=24.6 kg/m²; mean age= 39 years; total cholesterol=226 mg/dL; TG=149 mg/dL] without metabolic syndrome, diabetes, hypertension underwent (60 min/day, 2 to 3 times/week) at an intensity 60-80% age-predicted maximal heart rate for 16 weeks. Lipoprotein cholesterol levels...
High-density lipoprotein-cholesterol (HDL-C) is a negative risk factor for cardiovascular events. Although several homogeneous HDL-C assays are available, their accuracy has not been validated, particularly in subjects with disease. We aimed to clarify whether concentrations measured by [HDL-C (H)] agree those determined the reference measurement procedures (RMP)] using ultracentrifugation and precipitation heparin-manganese reagent fresh clinical samples.HDL-C samples from 48 healthy 119...