A5102901918- Luminescence Properties of Advanced Materials
- Gold and Silver Nanoparticles Synthesis and Applications
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Luminescence and Fluorescent Materials
- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Copper-based nanomaterials and applications
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemistry and Biological Activities
- Random lasers and scattering media
- Inflammasome and immune disorders
- Autophagy in Disease and Therapy
- Bioactive natural compounds
- Biological and pharmacological studies of plants
- Phytochemicals and Antioxidant Activities
- Atherosclerosis and Cardiovascular Diseases
- Phytochemical compounds biological activities
- Natural Compound Pharmacology Studies
- Solar-Powered Water Purification Methods
- Cholesterol and Lipid Metabolism
- Advanced Fiber Laser Technologies
- Spinal Cord Injury Research
- Metamaterials and Metasurfaces Applications
- Plasmonic and Surface Plasmon Research
Henan Polytechnic University
2021-2025
Shaanxi Normal University
2018-2024
Xi'an Medical University
2024
China Pharmaceutical University
2015-2023
Sun Yat-sen University
2020-2022
Xi'an Honghui Hospital
2021
Xi'an Jiaotong University
2021
Yale University
2020
Peking University
2013-2018
Changchun 208 Hospital
2018
ABSTRACT Chinese yam ( Dioscorea opposita Thunb. cv. Tiegun) has been utilized in traditional medicine and as a food source for centuries. However, the metabolite profiles antioxidant activities of by‐product peel have not studied sufficiently. Thus, to effectively identify active metabolites peel, we employed UHPLC–MS/MS‐based widely targeted metabolomics on from loessial soil (LPCY) sandy (SPCY). A total 1054 were identified, comprising 379 primary metabolites, 528 secondary 147 other...
Abstract Aims This study aimed to investigate whether electroacupuncture (EA) promotes the survival and synaptic plasticity of hippocampal neurons by activating brain‐derived neurotrophic factor (BDNF)/tyrosine receptor kinase (TrkB)/extracellular signal‐regulated (Erk) signaling, thereby improving spatial memory deficits in rats under SD. Methods In vivo, Morris water maze (MWM) was used detect effect EA on learning memory, at same time Western blotting (WB), immunofluorescence (IF),...
Frutescones H-R (1-11), new sesqui- or monoterpene-based meroterpenoids, were isolated from the aerial parts of Baeckea frutescens. Their structures and absolute configurations established by means spectroscopic analyses (HRESIMS, 1D 2D NMR, ECD), as well single-crystal X-ray crystallography 1, (-)-7, 9. The anti-inflammatory activities all isolates evaluated measuring their inhibitory effects on NO production in LPS-stimulated RAW 264.7 macrophages, structure-activity relationships 1-11 are...
Frutescone A-G [(1-6), (+)-7, (-)-7], a new group of naturally occurring tasmanone-based meroterpenoids, were isolated from the aerial parts Baeckea frutescens L. Compounds 1 and 4 featured rare carbon skeleton with an unprecedented oxa-spiro[5.8] tetradecadiene ring system, existing as two favored equilibrating conformers in CDCl3 solution, identified by variable-temperature NMR. The regioselective syntheses 4-7 achieved concise manner biomimetically inspired key hetero-Diels-Alder reaction...
Vascular endothelial cell injury induced by high glucose (HG) plays an important role in the occurrence and development of diabetic vascular complications. Yellow tea has a protective effect on cells. However, molecular mechanisms underlying this are unclear. In study, effects n-butanol fraction Huoshan large-leaf yellow extract (HLYTBE) were investigated using human umbilical vein cells (HUVECs) mice. HUVECs, HLYTBE significantly reduced production reactive oxygen species, increased...
Abstract Vascular endothelial cell (VEC) injury is a key factor in the development of diabetic vascular complications. Homoplantaginin (Hom), one main flavonoids from Salvia plebeia R. Br. has been reported to protect VEC. However, its effects and mechanisms against endothelium remain unclear. Here, effect Hom on VEC was assessed using high glucose (HG)‐treated human umbilical vein cells db/db mice. In vitro, significantly inhibited apoptosis promoted autophagosome formation lysosomal...
Although traceroute has the potential to discover AS links that are invisible existing BGP monitors, it is well known common approach for mapping router IP addresses numbers based on routing tables highly error-prone. We develop a systematic framework quantify errors of measurement in AS-level topology inference. In comparing traceroute-derived paths with paths, we take novel identifying mismatched path segments and then inferring causes these mismatches through set tests. Our results show...
Abstract Multiple sclerosis (MS) is a chronic disease that characterized by demyelination and neuronal damage. Experimental autoimmune encephalomyelitis (EAE) mice are used to model the progression of MS mirror MS-like pathology. Previous researches have confirmed inhibition NLRP3 inflammasome significantly alleviated severity EAE spinal cord, but its effect on damage oligodendrocyte loss in brain remains unclear. In this study, female C57BL/6 were immunized with MOG35–55 PTX establish...
Spinal cord injury (SCI) invariably results in neuronal death and failure of axonal regeneration. This is attributed mainly to the hostile microenvironment poor intrinsic regrowth capacity injured spinal neurons. We have reported previously that electro-acupuncture on Governor Vessel acupoints (GV-EA) can promote survival regeneration cord. However, underlying mechanism for this has remained uncertain. The present study aimed explore neural afferent pathway GV-EA stimulation possible by...
Rare-earth-doped upconversion luminescence has attracted extensive attention due to its narrow-band and wide-range emission spectra, which cover biological optical communication windows. For direct laser excitation, the photoluminescence of nanoparticles is inevitably involved in excitation signals luminescence, limiting application high background noise, heating, low quantum yield rare-earth-doped photoluminescence. Here, multiplasmons-excited was investigated by employing propagating...
Palmitic acid (PA)-induced vascular endothelial inflammation plays a pivotal role in the occurrence and development of diseases. The present study was conducted to examine effect homoplantaginin, main flavonoid from traditional Chinese medicine Salvia plebeia R. Br., on PA-treated human umbilical vein cells underlying molecular mechanism. Firstly, we found that homoplantaginin (0.1, 1, 10 μM) dose-dependently reduced expression toll-like receptor-4 evoked by PA (100 μM). inhibitory further...
Abstract All‐optical responsive nanomaterials, which can rapidly switch between two stable states, have been regarded as the next‐generation memories due to their potential realize binary information storage and implement on‐chip, integrated photonic neuromorphic systems. Rare earth oxides are preeminent candidates owing extraordinary luminescent stability narrow optical transitions. However, lack of simple effective switches, it is difficult all‐optical data storage, encoding, retrieval by...
A new skeleton of diterpenoid, 1,2,3,4,4α,9,10,10α-octahydro-(4α-hydroxyymethyl) -1,1-dimethyl-9-(1-methylethyl)-(2S,3S,4αR,9R,10αS)-2,3,5,7-phenanthrenetertrol, named plebeianiol (1), along with four known diterpenoids (2–5), were isolated from Salvia plebeia R. Br. Their structures determined on the basis spectral analysis. In bioactivity tests, compounds 1, 2 and 5 showed 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities IC50 values 20.0–29.6 µM. addition, these three had...
A novel thermo-plasmonic-assisted scheme for precise control of ion doping and local structure micro/nanomaterials with single-particle spectroscopy methods.
Localized surface plasmon has been extensively studied and used for the photocatalysis of various chemical reactions. However, different contributions between resonance interband transition in not well understood. Here, we study photothermal hot electrons effects crystal transformation by combining controlled experiments with numerical simulations. By photo-excitation NaYF 4 : Eu 3+ @Au composite structure, it is found that plasmonic catalysis much superior to experiments, owing generated...
Surface modified NaYF4:Yb3+/Er3+/Zn2+ upconversion nanoparticles were obtained by using branched polyethylenimine (PEI). Strong fluorescence emission was observed and the influence of copper ions on PEI-modified investigated. It found that can be quenched through luminescence resonance energy transfer from particle to ions. The results show PEI nanoparticle used as a fluorescent probe for highly sensitive selective detection
Ethyl rosmarinate (RAE) is one of the active constituents from Clinopodium chinense (Benth.) O. Kuntze, which used for diabetic treatment in Chinese folk medicine. In this study, we investigated protective effect RAE on high glucose-induced injury endothelial cells and explored its underlying mechanisms. Our results showed that both rosmarinic acid (RA) increased cell viability, decreased production reactive oxygen species (ROS), attenuated apoptosis a dose-dependent manner, as evidenced by...