- Analytical Chemistry and Chromatography
- Electrospun Nanofibers in Biomedical Applications
- Biosensors and Analytical Detection
- Microfluidic and Capillary Electrophoresis Applications
- Advanced biosensing and bioanalysis techniques
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- Mass Spectrometry Techniques and Applications
- Supercapacitor Materials and Fabrication
- Pancreatic function and diabetes
- Analytical chemistry methods development
- Innovative Microfluidic and Catalytic Techniques Innovation
- Amino Acid Enzymes and Metabolism
- Protein purification and stability
- Endoplasmic Reticulum Stress and Disease
- Covalent Organic Framework Applications
- Advanced Chemical Sensor Technologies
- Diabetes and associated disorders
- Dyeing and Modifying Textile Fibers
- Congenital heart defects research
- Neurogenesis and neuroplasticity mechanisms
- Epigenetics and DNA Methylation
- Adipose Tissue and Metabolism
- Acupuncture Treatment Research Studies
- Diabetes Treatment and Management
Ningbo University
2018-2025
Jiangnan University
2021-2025
Anhui University of Traditional Chinese Medicine
2024-2025
Nanjing Drum Tower Hospital
2025
State Key Laboratory of Food Science and Technology
2021-2024
Fujian Medical University
2024
Anhui Provincial Hospital
2022-2024
Anhui Medical University
2023-2024
Huashan Hospital
2014-2022
Fudan University
2014-2022
A hybrid core–shell material based on carbon nanofibers and a 2D conductive metal–organic framework has been fabricated into flexible free-standing membrane as an electrode for supercapacitors.
Abstract Chronic obstructive pulmonary disease (COPD) is a chronic, progressive, and lethal lung with few treatments. Formononetin (FMN) clinical preparation extract extensive pharmacological actions. However, its effect on COPD remains unknown. This study aimed to explore the underlying mechanisms of FMN COPD. A mouse model was established by exposure cigarette smoke (CS) for 24 weeks. In addition, bronchial epithelial BEAS‐2B cells were treated CS (CSE) h in vitro FMN. significantly...
To explore the role of retinal and choroidal parameters obtained via optical coherence tomography (OCT) angiography (OCTA) in predicting thyroid-associated ophthalmopathy (TAO) activity, providing a scientific basis for improved clinical diagnosis treatment. This study included 90 active TAO patients (178 eyes), 69 inactive (138 66 healthy individuals (132 eyes). It compared magnetic resonance imaging structural differences, analyzed correlations between these parameters, developed...
Co-electrospinning is a new branch of nanotechnology for producing composite nanofibers with collective functions and special fiber structures. Helical fibers in nanoscale have been increasing interest because their unique characteristics. In this work, we report the fabrication helical polyurethane poly(m-phenylene isophthalamide) by co-electrospinning system an off-centered core–shell spinneret. High-speed photography three-dimensional (3D) electric field simulation are carried out to help...
Triphenylmethane (TPM) fish drug residues and their metabolites exist in many aquiculture waters can cause significant harm to consumers. Rapid, accurate, simultaneous detection of foods is protecting the safety aquatic products. In study, a new type polydopamine coated polydimethylsiloxane (PDMS-PDA) stir bar was prepared for automatic sorptive extraction enrichment malachite green, leucomalachite crystal violet, leucocrystal violet which are common TPM drugs used aquaculture. The surface...
To observe the effects of electroacupuncture (EA) at "Zusanli" (ST36) and "Feishu" (BL13) points on Cortactin cytoskeletal stability pulmonary endothelial cells in mice with chronic obstructive disease (COPD), to explore mechanism by which EA alleviates inflammatory damage COPD. The C57BL/6 were randomly divided into 5 groups:normal group, model small interfering RNA (si-Cortactin) si-Cortactin + 10 each group. A COPD was established through 12 weeks cigarette exposure. Nasal instillation...
Organ hypertrophy can result from enlargement of individual cells or cell proliferation both. Activating mutations in the serine-threonine kinase Raf cause cardiac and contribute to Noonan syndrome humans. Cardiac-specific expression activated also causes Drosophila melanogaster. We found that Yorkie (Yki), a transcriptional coactivator Hippo pathway regulates organ size, is required for Raf-induced flies. Although aberrant activation Yki orthologs stimulates hyperplasia mice,...
Early apoptosis real-time detection by label-free SERS based on externalized phosphatidylserine using<italic>in situ</italic>synthesized silver nanoparticles.
As an important branch of ancient Chinese silk dyeing and printing technology, alkali degumming utilizes agents to degum raw silk, creating differences in fiber water absorption, dye uptake, optical characteristics between degummed non-degummed areas achieve localized pattern formation.Based on the processes Silk Gauze using alkaline boiling, steaming, gel, this study compares effects these three techniques under different conditions agent dosage, hot press temperature, duration. The...
The pineal hormone melatonin influences the secretion of insulin by pancreatic islets via G‑protein‑coupled receptors 1 and 2 that are expressed in β‑cells. Genome‑wide association studies indicate receptor 1B (MTNR1B) single nucleotide polymorphisms tightly associated with type diabetes mellitus (T2DM). However, underlying mechanism is unclear. Raf‑1 serves a critical role mitogen‑activated protein kinase (MAPK) pathways β‑cell survival proliferation and, therefore, may be involved which...
Transcription factor 7-like 2 (TCF7L2), which previously known as TCF-4, is a major form of transcription involved in the downstream WNT signaling and exhibits strongest association to diabetes susceptibility. Although we still do not know mechanistically how TCF7L2 exerts its physiological functions on pancreatic endocrine cells, it had been suggested that may directly affect β-cell function by regulating activation PI3K/AKT pathway.MIN6 cells were transfected with knockdown virus or...