A5100369518- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Preterm Birth and Chorioamnionitis
- Infant Nutrition and Health
- Dementia and Cognitive Impairment Research
- Pediatric Urology and Nephrology Studies
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Neonatal Health and Biochemistry
- Urinary Tract Infections Management
- Neonatal and fetal brain pathology
- Retinopathy of Prematurity Studies
- Cardiac Arrhythmias and Treatments
- Respiratory Support and Mechanisms
- Neurological Disease Mechanisms and Treatments
- Clostridium difficile and Clostridium perfringens research
- Assisted Reproductive Technology and Twin Pregnancy
- Full-Duplex Wireless Communications
- Ultrasound in Clinical Applications
- Phytochemistry Medicinal Plant Applications
- Spinal Fractures and Fixation Techniques
- Corneal Surgery and Treatments
- Cardiovascular Conditions and Treatments
- Complementary and Alternative Medicine Studies
- Alzheimer's disease research and treatments
Keimyung University
2008-2025
CHA University
2025
A.T. Still University
2025
Catholic University of Korea
2024
Keimyung University Dongsan Medical Center
2018-2021
Sungkyunkwan University
2011-2014
Samsung Medical Center
2011-2014
Neurology, Inc
2011
Dongguk University
2008
Korea Research Institute of Bioscience and Biotechnology
2006
Background We hypothesized that hidden malignancy could be detected in patients with cryptogenic stroke without active cancer when they showed the distinctive characteristics of cancer-related stroke. Methods and Findings Among 2,562 consecutive acute ischemic stroke, were analyzed categorized into two groups according to presence cancer: (cancer-related CA-stroke) group (CR-stroke) group. Patients lung also recruited for comparison purposes (CA-control). Clinical factors, lesion patterns on...
Cerebrovascular disease (CVD) and Alzheimer are significant causes of cognitive impairment in the elderly. However, few studies have evaluated relationship between CVD β-amyloid burden living humans or their synergistic effects on cognition. Thus, there is a need for better understanding mild (MCI) before clinical deterioration begins.
We explored GA, BW, Apgar score, CRIB II and serum albumin levels as univariate predictors of mortality in extremely low birth weight infants. Medical records 564 infants were reviewed retrospectively. The grouped survivors (group I), expired ≤ 7th postnatal day II), > III). predictive value for gestational age, weight, scores at 1 5 min, clinical risk index babies first lowest was assessed by calculating the associated area under curve (AUC) receiver operating characteristic (ROC) curves....
The early detection of neurodegenerative diseases necessitates the identification specific brain-derived biomolecules in peripheral blood. In this context, our investigation delineates role amyloid precursor-like protein 1 (APLP1)—a predominantly localized oligodendrocytes and neurons—as a previously unidentified biomarker extracellular vesicles (EVs). Through rigorous analysis, APLP1 + EVs from human sera were unequivocally determined to be cerebral origin. This assertion was corroborated...
This study aimed to determine whether there are relationships between vertical facial patterns, cervical posture, and curvature types. Ninety-two adult females with skeletal Class I were retrospectively analyzed divided into hypodivergent, normovergent, hyperdivergent groups based on the mandibular plane angle nasion–sella line. Variables representing craniocervical posture (sagittal axis, SVA; inclination angle, CIA) measured. Differences in among assessed. Cervical curvatures classified...
The tumor-associated glycoprotein (TAG)-72 is expressed in the majority of human adenocarcinomas but rarely most normal tissues, which makes it a potential target for diagnosis and therapy variety cancers. Here we describe construction, affinity maturation, biological characterization an anti-TAG-72 humanized antibody with minimum immunogenicity. was constructed by grafting only specificity-determining residues (SDRs) within complementarity-determining regions (CDRs) onto homologous...
Early prediction of intraventricular hemorrhage (IVH) in very low-birthweight infants (VLBWIs) remains challenging because multifactorial risk factors. IVH often occurs within a few hours after birth, yet its onset cannot be reliably predicted using clinical symptoms or vital signs such as blood pressure heart rate. Accurate early is critical for timely intervention but due to the limited feasibility current methods resource-constrained settings. Traditional require advanced equipment and...
Carotid artery stenosis is an important etiologic factor of stroke related to coronary bypass surgery. We evaluated clinical and laboratory factors identify biomarkers for pre-existing carotid in patients undergoing surgery.Between June 2006 September 2008, 811 aged ≥50 years underwent preoperative duplex scanning as part a assessment nonemergency cardiac procedures. Of these, 54 with previous or transient ischemic attack were excluded. The association between various was analyzed by...
The aim of this study was to evaluate the diagnostic accuracy urinary biomarkers, such as neutrophil gelatinase-associated lipocalin (uNGAL) and β-2 microglobulin (uB2MG), in early detection tract infection (UTI) infants aged <3 months with fever.A total 422 (male:female=267:155; mean age, 56.4 days), who were admitted for fever, retrospectively included study. We compared uNGAL uB2MG between UTI non-UTI groups at time admission. sensitivity, specificity, accuracy, area under curve (AUC) use...
Prenatal and perinatal infections inflammation appear to associated with the development of retinopathy prematurity (ROP). In this study, we evaluated whether inflammatory mediators in amniotic fluid (AF) retrieved during cesarean delivery influence ROP very low birth weight (VLBW) infants. This retrospective study included 16 32 VLBW infants who did not develop any stage ROP, respectively. Each infant was matched 2 without based on days ventilation care, gestational age, weight. AF obtained...
Objectives: The purpose of this study was to determine patient characteristics and other factors associated with discontinuation complementary alternative medicine (CAM) among cancer patients in Korea. Methods: A national, multicenter, cross-sectional survey performed which 674 2,661 were analyzed for their use CAM after diagnosis. Multiple logistic regression used identify the related discontinuation. Results: Among surveyed patients, 25.3% (674 2,661) had CAM, whereas 38.3% (258 674) those...
The purpose of this study was to evaluate prognostic factors associated with surgical ligation for patent ductus arteriosus (PDA) in extremely preterm infants born at the limits viability.Ninety who were 23-25 weeks gestation and received included their cases retrospectively reviewed.Infants classified into two different groups: survivors no major morbidity (N), nonsurvivors or any (M).Clinical characteristics compared between groups.Possible derived from comparison further tested by...
Progressive multifocal leukoencephalopathy (PML) is a demyelinating central nervous system disease caused by JC virus (JCV) reactivation in immunocompromised patients. The course of PML often progressive, fatal and at present, there are few reports on successful treatment outcomes.A 45-year-old man with systemic sarcoidosis presented rapidly progressive dementia right hemiparesis. patient was diagnosed as confirmed via brain biopsy JCV PCR. With combination cidofovir mirtazapine, significant...
We investigated fecal calprotectin (FC) levels in preterm infants with and without feeding intolerance (FI), compared the FC according to type of feeding.The medical records 67 premature were reviewed retrospectively. The fully enteral-fed classified into two groups; FI group (29 infants) control (31 infants). Seven necrotizing enterocolitis, sepsis, perinatal asphyxia excluded. If breast milk (BM) or formula (PF) could not be tolerated by FI, amino acid-based (AAF) was tried temporarily....
In this study, we investigated the clinical features and prognostic factors of early-onset sepsis (EOS) in neonatal intensive care unit (NICU) patients.A retrospective analysis was conducted on medical records from January 2010 to June 2017 (7.5 years) a university hospital NICU.There were 45 cases EOS (1.2%) 3,862 infants. The most common pathogen responsible for group B Streptococcus (GBS), implicated 10 (22.2%), followed by Escherichia coli, 9 (20%). frequency gram-positive higher term...
In accordance with the guidelines for expectant management of women exposed to previable preterm premature rupture membrane, we compared neonatal outcomes according latent period from membrane delivery among extremely infants maternal using Korean Neonatal Network database. Of 3,305 born at 23-27 weeks' gestation between 2014 and 2017 who were registered in Network, 1,464 pregnant membrane. The short latency group was defined as a < 7 days (n = 450), whereas prolonged ≥ 434). Using...
Purpose: To evaluate the refractive outcomes after ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) combined with phacoemulsification and intraocular lens implantation (triple procedure) in South Korean population.Methods: This retrospective observational study included 37 eyes of 36 patients who underwent UT-DSAEK triple procedure between 2012 2021 a single tertiary hospital. Preoperative postoperative parameters at 1, 3, 6, 12 months were observed.Results: At...
Abstract As increased oxidative stress causes mortality and morbidities like bronchopulmonary dysplasia (BPD) retinopathy of prematurity (ROP) in very low birth weight infants (VLBWIs), the conundrum improved survival but ROP observed with high oxygen saturation target range 91–95% is difficult to explain. To determine rate-dependent variation treatment rate, 6292 surviving eligible VLBWIs registered Korean Neonatal Network were arbitrarily grouped according rate at 23–24 weeks’ gestation as...
Purpose:We aimed to compare the clinical findings, including morbidity, duration of parenteral nutrition, and length hospital stay between very low birth weight infants (VLBWIs) fed bovine milk-based formula (BOV) VLBWIs human breast milk (HBM) in a neonatal intensive care unit (NICU).Methods: admitted NICU Dongsan Medical Center, Keimyung University, were enrolled.Infants born from March August 2014 (n=28) BOV (the group), those September December (n=18) HBM group).Pasteurized (heating at...