Qing Wen

ORCID: 0000-0001-8967-3460
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About
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Research Areas
  • Thyroid Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Diagnosis and Treatment
  • Nanoplatforms for cancer theranostics
  • Ultrasound in Clinical Applications
  • Pleural and Pulmonary Diseases
  • MRI in cancer diagnosis
  • Cancer Research and Treatments
  • Topic Modeling
  • Natural Language Processing Techniques
  • Pancreatic and Hepatic Oncology Research
  • Head and Neck Anomalies
  • HIV Research and Treatment
  • S100 Proteins and Annexins
  • Thyroid and Parathyroid Surgery
  • Speech Recognition and Synthesis
  • Liver Disease and Transplantation
  • Neurofibromatosis and Schwannoma Cases
  • Peptidase Inhibition and Analysis
  • Adolescent and Pediatric Healthcare
  • Childhood Cancer Survivors' Quality of Life
  • Soft tissue tumor case studies
  • Oral and Maxillofacial Pathology
  • Extracellular vesicles in disease
  • Medical Imaging and Pathology Studies

Second Affiliated Hospital of Zhejiang University
2019-2023

Zhejiang University
2008-2023

Pingxiang University
2011-2022

Creative Commons
2020

Chemodynamic therapy (CDT) strategies rely on the generation of reactive oxygen species (ROS) to kill tumor cells, with hydroxyl radicals (•OH) serving as key mediators cytotoxicity in this setting. However, efficacy CDT approaches is often hampered by properties microenvironment (TME) and associated limitations Fenton reaction that constrains ROS generation. As such, there a pressing need for design new nanoplatforms capable improving outcomes. In study, an Fc-based metal–organic framework...

10.1021/acsami.2c19476 article EN ACS Applied Materials & Interfaces 2023-01-26

The proliferation of deepfake content has motivated a surge detection studies. However, existing methods in the audio area exclusively work English, and there is lack data resources other languages. Cross-lingual detection, critical but rarely explored area, urges more study. This paper conducts first comprehensive study on cross-lingual perspective detection. We observe that English enriched algorithms can teach detector knowledge various spoofing artifacts, contributing to performing...

10.1145/3543507.3583222 article EN Proceedings of the ACM Web Conference 2022 2023-04-26

Abstract Background Pancreatic cancer remains among the most prevalent and aggressive forms of cancer. While immunotherapeutic treatment strategies have shown some promise in affected patients, benefits these interventions been limited by insufficient tumor infiltration activated T cells. Results Here, Titanium diselenide (TiSe 2 ) nanosheets were synthesized with good stability. When exposed to ultrasound (US), TiSe served as a reliable nano-sensitizer capable inducing large amounts...

10.1186/s12951-022-01659-4 article EN cc-by Journal of Nanobiotechnology 2022-10-15

Rationale: The diagnostic yield of traditional ultrasound-guided pleural biopsy remains unsatisfactory, particularly when the thickness is ⩽5 mm and/or no nodules are detected. Pleural ultrasound elastography (UE) has a better than for malignant effusion (MPE). However, studies on UE-guided biopsies lacking. Objectives: To evaluate feasibility and safety biopsy. Methods: In this multicenter prospective single-arm trial, patients with whose was were enrolled between July 2019 August 2021. its...

10.1513/annalsats.202212-1047oc article EN Annals of the American Thoracic Society 2023-04-25

To determine the diagnostic performance and inter-reader agreement of contrast-enhanced ultrasound liver imaging reporting data system (CEUS-LI-RADS) for diagnosing hepatocellular carcinoma (HCC) in high-risk patients. In this prospective study, CEUS-LI-RADS categories (LR-5 predicting HCC) were assigned by six blinded readers compared to definitive HCC diagnosis patients with cirrhosis per 2017 China Liver Cancer Guidelines (CLCG). CEUS features recorded 96 histology-proven lesions. The...

10.1055/a-1168-6321 article DE Ultraschall in der Medizin - European Journal of Ultrasound 2020-07-08

BRAF V600E mutation was proved to be associated with thyroid cancer. Papillary carcinoma (PTC) positive might have a more aggressive behavior. We investigated the correlation of contrast-enhanced ultrasound (CEUS) features 600VE in PTC.The medical records 1,199 patients 1,315 nodules who underwent CEUS prior fine needle aspiration (FNA) from January 2016 March 2018 were retrospectively reviewed. The their enhancement assessed eight aspects: degree enhancement, method homogeneity completeness...

10.21037/jtd.2019.11.78 article EN Journal of Thoracic Disease 2019-12-01

The aim of the present study was to investigate benefits combining contrast-enhanced ultrasound (CEUS) and strain elastography (SE) for diagnosis thyroid nodules with non-diagnostic fine-needle aspiration cytology (FNAC) results. Between October 2013 March 2017, CEUS SE were performed in 226 patients (236 nodules) FNAC results prior thyroidectomy. diagnostic value CEUS, their combination (CEUS+SE) distinguishing malignant from benign evaluated, using surgical pathology as a reference....

10.3892/ol.2019.11058 article EN Oncology Letters 2019-11-05

The Hermite–Hadamard–Fejér-type inequality is a powerful tool for studying lower and upper estimations the integral average of convex function. In this paper, we adopt Hölder’s to establish inequalities via Katugampola fractional integrals function [Formula: see text], where text] an s-convex on symmetric with respect text]. Our results are generalizations some earlier results. At end illustrative examples about given support our

10.1142/s0218348x22501316 article EN Fractals 2022-06-09

10.1007/s10483-011-1427-8 article EN Applied Mathematics and Mechanics 2011-04-01

Abstract Introduction: Congenital cystic adenomatoid malformation (CCAM) is a rare developmental lung abnormality, that typically manifests in neonates and infants but rarely adults. Ultrasound an important method of diagnosing CCAM infants; however, few articles have reported the value transthoracic ultrasound diagnosis Patient concerns: We present case 34-year-old woman with cavitary lesion her left lower lobe, suggested chronic inflammation. Diagnosis: The patient underwent examination...

10.1097/md.0000000000023505 article EN cc-by-nc Medicine 2020-12-04

Objective To evaluate the diagnostic and prognostic value of BRAF V600E mutation screening ultrasound-guided fine-needle aspiration (FNA) specimens in patients with thyroid nodule. Methods The status were assessed FNA 104 nodules before operations. The status, clinical, pathology records reviewed associations between these characteristics papillary cancer(PTC) analyzed. Results Seventy-one PTC 14 benign included this study. mutations found 57/71(80%) PTC. All had no mutation....

10.3760/cma.j.issn.1004-4477.2015.08.009 article EN Zhonghua chaosheng yingxiangxue zazhi 2015-08-25

This study aimed to describe the characteristics of superficial desmoid fibromatosis (DF) using two-dimensional and contrast-enhanced ultrasonography, intending improve diagnostic accuracy. We retrospectively analyzed 19 cases DF confirmed by surgery or core-needle biopsy in our hospital from January 2018 August 2020. All patients underwent ultrasound (CEUS) examination. Nineteen included 15 women 4 men, with an average age 33.37±12.13 years old. The mean size lesions was 4.78±1.99 cm. On...

10.3233/ch-211249 article EN Clinical Hemorheology and Microcirculation 2021-09-07

The aim was to retrospectively analyze the ultrasonographic and clinical characteristics of focal inflammatory masses malignant salivary gland by using B-mode ultrasound (US) contrast-enhanced (CEUS) for differential analysis.The features US CEUS were analyzed 19 cases 45 masses. All confirmed pathohistological examination.On US, incidence expansive growth patterns (44.4%, 20/45) significantly higher than that (15.8%, 3/19) (p = 0.029). rate lymphadenopathy surrounding glands (42.2%, 19/45)...

10.3233/ch-211151 article EN Clinical Hemorheology and Microcirculation 2021-05-25

Objective To evaluate the association of BRAF V600E mutation with sonographic features in patients papillary thyroid carcinoma. Methods A consecutive series 61 carcinoma(PTC) was evaluated by US and elastography before US-FNA, surgery.The PTCs were categorized into 2 groups according to results mutation, BRAF-positive BRAF-negative patients. The compared between patients. Results The detected 82% (50 61). There no significant difference PTC on including nodular size,...

10.3760/cma.j.issn.1004-4477.2016.09.012 article EN Zhonghua chaosheng yingxiangxue zazhi 2016-09-25

Objective To assess value of contrast enhanced ultrasound (CEUS) in TN staging pancreatic cancer and compared with computed tomography(CECT). Methods Seventy-eight cases confirmed by pathology were enrolled this study. All patients examined using CEUS CECT staged according to the 8th guideline pancreas tumors AJCC. The diagnostic accuracies CECT. Results The T N 80.8%, 78.2%, respectively. For CECT, 88.5%, There was no significant difference between staging(χ2=1.56, P=0.21)....

10.3760/cma.j.issn.1004-4477.2018.07.014 article EN Zhonghua chaosheng yingxiangxue zazhi 2018-07-25

Objective To invesitigate the application of contrast enhanced ultrasound in differentiating focal organizing pneumonia(FOP) and primary lung cancer. Methods The imaging data 23 cases with FOP(FOP group) 75 cancer(primary cancer on conventional were retrospectively analyzed. The size arrival time(AT) agent pattern two groups compared. ROC curve was created to determine most accurate AT for differential diagnosis. Results There no significant difference gender nodule between...

10.3760/cma.j.issn.1004-4477.2018.08.012 article EN Zhonghua chaosheng yingxiangxue zazhi 2018-08-25

Objective To assess the characterization and usefulness of contrast enhanced ultrasound (CEUS) to diagnose focal lesions pancreas in comparison computed tomography (CECT). Methods 177 cases solid confirmed by pathology were collected. The patterns diagnostic capability CEUS analyzed, these results compared with those CECT. Results The accuracies ultrasound, CECT 61.6% (109/177), 89.3% (158/177), 92.1% (163/177), respectively. There was no significant difference between...

10.3760/cma.j.issn.1007-631x.2018.10.013 article EN Zhonghua putong waike zazhi 2018-10-25

Objective To investigate the value of share wave elastography (SWE) combined with BRAFV600E in predicting central lymph nodes metastasis papillary thyroid carcinoma (PTC). Methods This study collected 217 PTC from patients diagnosed as by surgical pathology,all are confirmed conventional ultrasonography, SWE examination, BRAF V600E gene detection and neck dissection for preventive. Taking postoperative pathological results gold standard, independent t test was used to compared...

10.3877/cma.j.issn.1672-6448.2019.03.011 article EN Chin J Med Ultrasound(Electronic Edition) 2019-03-01

Background: The diagnostic yields of traditional ultrasound-guided pleural biopsy remain unsatisfactory, especially when the thickness is ≤ 5 mm and/or no nodules are detected. Pleural ultrasound elastography has a better yield than for malignant effusion (MPE). However, studies elastography-guided (UEPB) lacking. This study was designed to assess and safety UEPB diagnosing MPE.Methods: We prospectively enrolled patients with whose into group or flexible thoracoscopy (FT) between July 2019...

10.2139/ssrn.4115474 article EN SSRN Electronic Journal 2022-01-01
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