- Collagen: Extraction and Characterization
- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Polymer Surface Interaction Studies
- Periodontal Regeneration and Treatments
- Bone Tissue Engineering Materials
- Cell Adhesion Molecules Research
- biodegradable polymer synthesis and properties
- Osteoarthritis Treatment and Mechanisms
- Nanofabrication and Lithography Techniques
- 3D Printing in Biomedical Research
- Bone and Dental Protein Studies
- Enzyme Production and Characterization
- Marine Biology and Environmental Chemistry
- Monoclonal and Polyclonal Antibodies Research
- Antimicrobial agents and applications
- Antimicrobial Peptides and Activities
- Additive Manufacturing and 3D Printing Technologies
- Biocrusts and Microbial Ecology
- Supramolecular Self-Assembly in Materials
- Diatoms and Algae Research
- Algal biology and biofuel production
- Molecular Junctions and Nanostructures
- Advanced Sensor and Energy Harvesting Materials
- Retinal and Macular Surgery
CSIRO Manufacturing
2015-2025
Commonwealth Scientific and Industrial Research Organisation
2006-2024
Health Sciences and Nutrition
2023
Clayton Foundation
2016
Materials Science & Engineering
2011-2014
Cooperative Research Centre for Polymers
2012
Technologies pour la Santé
2006-2008
The University of Adelaide
2006
Australian Nuclear Science and Technology Organisation
2005
Australian National University
2005
Abstract A novel bone graft substitute comprising a porous, collagenous scaffold was biomimetically coated with hydroxyapatite using simulated body fluid solution chemistry method. The had porosity of approximately 85%, pore sizes between 30 μm and 100 μm. Glutaraldehyde vapor used to stabilize the scaffold, giving significantly increased thermal stability over an unstabilized as shown by differential scanning calorimetry. thin layer (<10 μm) crystalline deposited onto stabilized soaking...
Infections resulting from the formation of biofilms on medical devices remain a significant clinical problem. There is growing consensus that coatings displaying multiple defense mechanisms, such as low biofouling combined with surface active antimicrobial agents, required. Quorum sensing (QS) bacterial mechanism used to coordinate their collective behavior. QS can also be exploited for purposes, minimize colonization and biofilm by hindering communication. We have investigated poly(ethylene...
Collagens from a wide array of animals have been explored for use in tissue engineering an effort to replicate the native extracellular environment body. Marine-derived biomaterials offer promise over their conventional mammalian counterparts due lower risk disease transfer as well being compatible with more religious and ethical groups within society. Here, collagen type I derived marine source (Macruronus novaezelandiae, Blue Grenadier) is compared established porcine its potential...
Glutaraldehyde is a well-recognised reagent for crosslinking and stabilising collagens other protein-based materials, including gelatine. In some cases, however, the use of solutions can disrupt structure material, example, by causing rapid dispersion or distortions from surface interactions. An alternative approach that has been explored in number individual cases glutaraldehyde vapour. this study, effectiveness range different concentrations reservoir providing vapour, 5% to 25% (w/v), at...
Herein, a family of thiourea containing silicone-based photoresins suitable for creating silicone objects with excellent elasticity was developed use in conventional digital light processing 3D printers. Rapid manufacturing products is highly desirable small-volume manufacturing, especially the application customer-specific medical devices. However, because their intrinsic high viscosity and lack intermolecular interactions, printing remains an ongoing challenge as resins are not...
When provoked, Notaden bennetti frogs secrete an exudate which rapidly forms a tacky elastic solid ("frog glue"). This protein-based material acts as promiscuous pressure-sensitive adhesive that functions even in wet conditions. We conducted macroscopic tests air to assess the tensile strength of moist glue (up 78 ± 8 kPa) and shear dry (1.7 0.3 MPa). also performed nanomechanical measurements water determine adhesion (1.9−7.2 nN or greater), resilience (43−56%), modulus (170−1035 collected...
Abstract Articular cartilage tissue engineering procedures require the transplantation of chondrocytes that have been expanded in vitro. The expansion is carried out for a considerable time and can lead to modulation cell phenotype. However, microcarrier cultures shown allow while maintaining Here, we used biodegradable polyester poly(lactide‐ co ‐glycolide) (PLGA) form microspheres irregular shaped microparticles with diameter between 47 210 μm. Surface modification particles was by ammonia...
Abstract There have been concerns regarding the suitability of bovine collagen as a biomaterial since emergence spongiform encephalopathy. Consequently, collagens from other species may be used if they can meet appropriate standards, including negligible or lack immunogenicity. In this study, potential immunogenicity both monomeric and pepsin‐solubilized chicken compared with commercial, that is approved for biomedical implantation. All were poor immunogens ovalbumin. No IgE responses...
We describe a method for grafting PEG-based polymer chains of variable surface density using substrate independent approach, allowing from virtually any material substrate. The approach relies upon initial coupling macroinitiator to plasma treated surfaces. is novel random terpolymer containing ATRP initiator residues, strongly negatively charged groups, and carboxylic acid moieties that facilitate covalent anchoring. Surface-initiated (SI-ATRP) polyethylene glycol methyl ether methacrylate...
Collagen is an important component for cosmetic formulation, where it effective natural humectant with high substantivity. Commercial collagen preparations have a wide range of properties. In the present study, various techniques been used to examine three distinct commercial collagens that illustrate properties are available. The usefulness assessing quality and batch‐to‐batch variation discussed. results indicate there several simple, cheap methods such as gel electrophoresis provide...
In this novel platform, a micropatterned polymer brush was obtained by grafting poly(poly(ethylene glycol) methyl ether methacrylate) (poly(PEGMA)) from thin macroinitiator film using atom transfer radical polymerization (ATRP). A pattern of holes formed in the taking advantage its spontaneous dewetting above glass transition temperature bottom polystyrene film, driven unfavorable intermolecular forces. Patterning can be achieved at length-scales few hundred nanometers to several tens...