A5083395070- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Obstructive Sleep Apnea Research
- SARS-CoV-2 and COVID-19 Research
- Asthma and respiratory diseases
- Inflammatory Biomarkers in Disease Prognosis
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Lung Cancer Research Studies
- Neuroscience of respiration and sleep
- Cytokine Signaling Pathways and Interactions
- Emergency and Acute Care Studies
- Congenital Diaphragmatic Hernia Studies
- Lung Cancer Diagnosis and Treatment
- Vasculitis and related conditions
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Chronic Disease Management Strategies
- Heart Rate Variability and Autonomic Control
- Respiratory Support and Mechanisms
- Inhalation and Respiratory Drug Delivery
- Lung Cancer Treatments and Mutations
- Inflammasome and immune disorders
- Tuberculosis Research and Epidemiology
- Delphi Technique in Research
University of Kragujevac
2012-2023
Clinical Centre of Kragujevac
2012-2023
Background: The successful management of asthma and chronic obstructive pulmonary disease (COPD) mostly depends on adherence to inhalation drug therapy, the usage which is commonly associated with many difficulties in real life. Improvement patients' technique could lead a better outcome treatment COPD. Objective: aim this study was assess utility clinical functional control COPD during 3-month follow-up. Methods: A total 312 patients or who used dry powder Turbuhaler were enrolled...
Objective: To assess the direct and indirect costs of diagnosing treating community-acquired pneumonia (CAP), correlating those with CAP severity at diagnosis identifying major cost drivers. Methods: This was a prospective analysis study using bottom-up costing. Clinical mortality risk were assessed index (PSI) mental Confusion-Urea-Respiratory rate-Blood pressure-age ≥ 65 years (CURB-65) scale, respectively. The sample comprised 95 inpatients hospitalized for newly diagnosed CAP. run from...
Bearing in the mind that a variety of agents can contribute to genome instability, including viral infections, aim this study was analyze DNA damage hospitalized COVID-19 patients and its relationship with certain laboratory parameters. The potential impact applied therapy chest X-rays on also estimated. population included 24 severely 15 healthy control subjects. level measured as genetic index (GDI) by comet assay. standard methods certified enzymatic reagents for appropriate autoanalyzers...
Background The coronavirus disease 2019 (COVID-19) pandemic has put pressure on healthcare services, forcing the reorganisation of traditional care pathways. We investigated how physicians taking severe asthma patients in Europe reorganised care, and these changes affected patient satisfaction, control future care. Methods In this European-wide cross-sectional study, surveys were sent to with a physician-diagnosis asthma, physician specialists between November 2020 May 2021. Results 1101 268...
Introduction/Aim. Lung cancer is a leading cause of mortality among patients with carcinomas. The aim this study was to point out risk factors for brain metastases (BM) appearance in IIIA (N2) stage nonsmall cell lung (NSCLC) treated three-modal therapy. Methods. We analyzed data obtained from 107 NSCLC surgically neoadjuvant frequency examined regarding age, sex, histological type and the size tumor, nodal status, sequence radiotherapy chemotherapy application chemotherapy. Results. Two...
Establishing a regional/national/international registry of patients suffering from chronic obstructive pulmonary disease (COPD) is essential for both research and healthcare, because it enables collection comprehensive real-life data large number individuals.The aim this study was to describe characteristics COPD the Serbian patient registry, investigate actual differences those among phenotypes.The with established in 2018 at University Kragujevac, Faculty Medical Sciences, based on an...
Community-acquired pneumonia (CAP) represents a potentially severe illness with high incidence and significant economic impact. The estimated varies from 1.6 to 13.4 cases/1000 inhabitants per year. Its burden of disease is attributed morbidity, mortality serious health care utilization expenditure throughout the world. identification determinants treatment costs could help in defining strategies for their reduction more efficient use existing resources. In this article, review literature...
Background: Early prediction of COVID-19 patients’ mortality risk may be beneficial in adequate triage and assessment. Therefore, we aimed to single out the independent morality predictors hospitalized patients among parameters available on hospital admission. Methods: An observational, retrospective−prospective cohort study was conducted 703 consecutive University Clinical Center Kragujevac between September December 2021. Patients were followed during hospitalization, in-hospital observed...
Background/Aim. There is an increasing number of studies on the existence systemic oxidative stress in patients with obstructive sleep apnea (OSA) which important mechanism linking OSA and endothelial dysfunction increased risk for cardiovascular diseases. Comorbidities must be also considered, especially obesity, as most source independently OSA. The aim this paper was to show if severity increases level markers reduces antioxidant capacity, from body mass index (BMI) nutritional status....
Bacground/Aim. Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality in pathology. However, apart from its own manifestations, this also characterized by systemic effects, including hypogonadism which described especially group men with COPD. The aim study was to evaluate risk factors for Methods. included 96 male patients COPD stable phase disease. All were checked concentration free testosterone serum, markers inflammation, tumor necrosis factor-?...
Vaccination is vital for achieving population immunity to severe acute respiratory syndrome coronavirus 2, but vaccination hesitancy presents a threat widespread immunity. Vaccine acceptance in chronic potentially immunosuppressed patients largely unclear, especially with asthma. The aim of this study was investigate the experience people asthma.Questionnaires about beliefs (including Attitudes Examination (VAX) scale, measure hesitancy-related beliefs), side-effects, asthma control and...
OPINION article Front. Public Health, 24 March 2015Sec. Epidemiology Volume 3 - 2015 | https://doi.org/10.3389/fpubh.2015.00050
Introduction/Objective. The origin of depressive disorder in chronic obstructive pulmonary disease (COPD) patients is still not completely known and probably caused by various factors. aim this study to establish the most important characteristics COPD who have disorder. Methods. Eighty-nine 65 demographically-matched referents without were included. All underwent lung function examination, gas exchange, nutritional status, dyspnoea level modified Medical Research Council (mMRC) scale...
<b>Introduction:</b> When considering oxidative stress in OSA must be considered and comorbidities, especially obesity. <b>The aim:</b> of this study is to show that if the increased weight increases level systemic markers reduced antioxidant capacity, independent nutritional status. <b>Methodology:</b> The included 32 patients with OSA. Based on results sleep subjects were divided into two groups (AHI≤15 AHI> 15). It estimated status using BMI body composition by whole-body DEXA scan....
Background and Objectives: The Baveno classification represents a new approach to the assessment of severity OSA (Obstructive sleep apnea), which takes significant comorbidities into account: atrial fibrillation, arterial hypertension, heart failure, stroke, diabetes mellitus, symptoms expressed through Epworth sleepiness scale (ESS). authors believe that facilitates better stratification patients with can be good guide for deciding on therapeutic clinical monitoring OSA, compared AHI...
Background/Aim. Peripheral muscle weakness and nutritional disorders, firstly loss of body weight, are common findings in patients with chronic obstructive pulmonary disease (COPD). The aim this study was to analyse the impact function parameters, status state peripheral skeletal muscles on exercise tolerance development dyspnea COPD patients. Methods. Thirty stable were analyzed. Standard tests, including spirometry, pletysmography, measurements diffusion capacity performed. 6-minute...
Introduction. Montelukast is a selective leukotriene receptor antagonist. One of side effects this drug class the Churg-Strauss syndrome (CSS). There still no reliable evidence whether expression could be masked by high doses corticosteroids and become expressed termination corticosteroid use, or it consequence antagonists use. Case report. Female patient, aged 49 years, was hospitalized with symptoms fever, dyspnea, cough increased sputum production occasional hemoptysis. She treated for...
Introduction. Asymptomatic Bochdalek hernia in adults is a rarity. The aim of this paper to present rare case among and point out significance clinical suspicion important role imaging techniques reaching the exact diagnosis abnormality. Case report. A patient, aged 68 years, came Clinic Pulmonology complaining constant dyspnea, coughing fatigue. Computed tomography (CT) findings were dominated by large rear right diaphragmatic with hernial sac that reached carina trachea urged principal...
Abstract The interactions of metal complexes with important biomolecules such as deoxyribonucleic acid (DNA) or bovine serum albumin (BSA) are responsible for their antitumor activity due to different modes interaction DNA and transport through the blood system cells tissues via albumin. Therefore, dinuclear palladium(II) complexes, [{Pd(en)Cl} 2 (μ-1,5-nphe)](NO 3 ) (Pd1) [{Pd(1,3-pd)Cl} (Pd2) (en is ethylenediamine, 1,3-pd 1,3-propylenediamine 1,5-nphe bridging 1,5-naphthyridine ligand)...
There is emerging evidence of prolonged recovery in survivors coronavirus disease 2019 (COVID-19), even those with mild COVID-19. In this paper, we report a case 39-year-old male excessive body weight and history borderline values arterial hypertension without therapy, who was mainly complaining progressive dyspnea after being diagnosed According to the recent guidelines on holistic assessment management patients had COVID-19, all preferred diagnostic procedures, including multidetector...
<b>Background:</b> Recently, much attention has been focused on patients with overlapping features of both asthma and COPD: those COPD overlap syndrome (ACOS). The aim the study was to estimated prevalence clinical characteristics ACOS in COPD. <b>The methodology:</b> This included 605 whose diagnosis based following criteria: age over 40 years, current or previous tobacco exposure, chronic respiratory symptoms airflow obstruction (post-bronchodilatator FEV<sub>1</sub>/FVC<0.70). All...
Background/Aim. Oxygen therapy is a necessary therapeutic method in treatment of severe chronic respiratory failure (CRF), especially phases acute worsening. Risks which are to be taken into consideration during this are: unpredictable increase carbon dioxide blood, carbonarcosis, acidosis and coma. The aim study was show the influence oxygen on changes arterial blood partial pressure. Methods. included 93 patients 104 admittances hospital due exacerbation CFR. majority (89.4%) had...