A5100724777- Neonatal Respiratory Health Research
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Cancer-related gene regulation
- Lung Cancer Treatments and Mutations
- Congenital Diaphragmatic Hernia Studies
- Ultrasound and Hyperthermia Applications
- Connective tissue disorders research
- Photodynamic Therapy Research Studies
- Antimicrobial Peptides and Activities
- Colorectal and Anal Carcinomas
- Sexual Differentiation and Disorders
- Infant Development and Preterm Care
- Gut microbiota and health
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer Immunotherapy and Biomarkers
- Pelvic and Acetabular Injuries
- Parathyroid Disorders and Treatments
- Reproductive System and Pregnancy
- Hip and Femur Fractures
- Medical Imaging and Pathology Studies
- Metabolism, Diabetes, and Cancer
- Colorectal Cancer Screening and Detection
- Amino Acid Enzymes and Metabolism
- RNA Research and Splicing
Hebei Medical University
2022-2025
Fourth Hospital of Hebei Medical University
2022-2025
Sun Yat-sen University
2025
Fujian Agriculture and Forestry University
2025
Nanjing Medical University
2009-2024
Jiangsu Province Hospital
2017-2024
Suzhou Municipal Hospital
2022
First Affiliated Hospital of Zhengzhou University
2021
North China University of Science and Technology
2017
China Pharmaceutical University
2009
Colorectal cancer (CRC) presents a complex tumor microenvironment influenced by genetic and microbial factors. Microbial DNA from the gut can translocate into bloodstream, forming circulating microbiome associated with prognosis clinicopathological features. This study investigates peripheral venous blood in CRC patients using 2bRAD-M sequencing evaluates its clinical significance. Peripheral samples 29 (19 males, 10 females; mean age 57 years) healthy controls were analyzed to assess...
This study explores the benefits of targeted-immunotherapy combination in third-line or beyond treatment for microsatellite stable (MSS) metastatic colorectal cancer (mCRC) a real-world setting.
Abstract Background Enolase 1 (ENO1) is a metabolic enzyme which participates in pyruvate synthesis and ATP production cells. Previously, differential expression of ENO1 was discovered villous tissues between recurrent miscarriage induced abortion. This study designed to explore whether influences the proliferation invasion trophoblasts related molecular mechanisms. Methods First, placental villus collected from (RM) patients women for abortion as well trophoblast‐derived cell lines detected...
Acute lung injury (ALI) is one of the most common clinical emergencies with limited effective pharmaceutical treatment in clinic, especially when it progresses to acute respiratory distress syndrome (ARDS). Currently, mesenchymal stem cells (MSCs) exhibit specific superiority for ALI/ARDS treatment. However, from different sources may result controversial effects on similar disease conditions. This study aimed determine human amnion-derived (hAMSCs) two ALI mice model. The administered...
Lorlatinib has been suggested as the therapeutic option for patients with ROS1-rearranged non-small-cell lung cancer (NSCLC) after ROS1 tyrosine kinase inhibitor (TKI) failure. However, mechanism mediating lorlatinib resistance not well elucidated in NSCLC. Post- options remain scarce.Herein, we describe a 31-year-old female patient stage IVB She received 2nd line treatment crizotinib chemotherapy failure and achieved partial response lasting 15 months. An NF1 p.G127Ter mutation emerged...
Despite evidence suggesting a significant role of pyruvate kinase muscle isozyme (PKM) in cancer development, its particular function colorectal (CRC) remains unclear. This study aimed to elucidate the specific and mechanism PKM isoforms, PKM1 PKM2, progression CRC.
Abstract Background Calciphylaxis, which mostly affects individuals with end-stage kidney disease (ESKD), is also known as calcific uremic arteriolopathy (CUA). It a rare and fatal that manifests calcification thrombosis of microvessels, ischemia, necrosis in skin tissues(ORPHA:280062). Histopathological features extracutaneous tissues CUA patients undergoing human amnion–derived mesenchymal stem cell (hAMSC) treatment remain unknown. Methods A female patient, treated hAMSCs for 20 months,...
This study explored the correlation between peripheral blood lipid levels and clinicopathological parameters in patients with advanced gastric cancer (GC), focusing on changes during disease progression. Pathological features serum profiles of 179 stage III-IV adenocarcinoma were analyzed. Lipid examined included total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL-C), low-density (LDL-C), very (VLDL-C), apolipoprotein AI (Apo AI), B B), lipoprotein(a) (Lp(a)), among...