A5072158785- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Synthesis and Reactions of Organic Compounds
- Synthesis of heterocyclic compounds
- Synthesis and Reactivity of Heterocycles
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Metal complexes synthesis and properties
- Organic Chemistry Cycloaddition Reactions
- Crystal structures of chemical compounds
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Chemical Reaction Mechanisms
- Asymmetric Synthesis and Catalysis
- Chemical Synthesis and Analysis
- Porphyrin and Phthalocyanine Chemistry
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Molecular Sensors and Ion Detection
- Synthesis of Organic Compounds
- Cyclopropane Reaction Mechanisms
- Chemical synthesis and pharmacological studies
- Fluorine in Organic Chemistry
- Synthesis and Characterization of Pyrroles
- Magnetism in coordination complexes
Lomonosov Moscow State University
2016-2025
Moscow State University
2014-2024
Chuvash State University
2004-2016
N.D. Zelinsky Institute of Organic Chemistry
2004-2016
Kazan Federal University
2008
Virginia Commonwealth University
2008
Universidad de Alcalá
2005
St. Petersburg State Technological Institute
2003
Institute of Chemistry of High-Purity Substances them. G.G.Devyatyh
2000
Central Research Institute for Machine Building
1999
Organic optoelectronics requires materials combining bright luminescence and efficient ambipolar charge transport. Thiophene-phenylene co-oligomers (TPCOs) are promising highly emissive with decent charge-carrier mobility; however, they typically show poor electron injection in devices, which is usually assigned to high energies of their lowest unoccupied molecular orbitals (LUMOs). A widely used approach lower the frontier energy levels a conjugated molecule its fluorination. In this study,...
A series of novel organotin(IV) complexes on the base 2-(N-3',5'-di-tert-butyl-4'-hydroxyphenyl)-iminomethylphenol (L) formulae Me2SnBr2(L)2 (1), Bu2SnCl2(L)2(2), Ph2SnCl2(L) (3), Ph2SnCl2(L)2 (4) Ph3SnBr(L)2 (5) were synthesized and characterized by 1H, 13C, 119Sn NMR, IR, ESI-MS elemental analysis. The crystal structures initial L complex 2 determined XRD method. It was found that crystallizes in orthorhombic syngony. distorted octahedron geometry around Sn center is observed structure 2....
Oxidative C–O coupling of oximes, <italic>N</italic>-hydroxyphthalimide, and <italic>N</italic>-hydroxybenzotriazole with pyrazolones <italic>via</italic> formation <italic>N</italic>-oxyl radicals is described.
Two series of organotin(IV) complexes with Sn–S bonds on the base 2,6‐di‐ tert ‐butyl‐4‐mercaptophenol ( L 1 SH ) formulae Me 2 Sn(L S) ); Et Bu 3 Ph 4 (L 5 6 7 = 3,5‐di‐ ‐butyl‐4‐hydroxyphenyl), together new ones [Me SnCl(L )] 8 ), SnCl ] 9 2‐(N‐3 ′ ,5 ‐di‐ ‐butyl‐4 ‐hydroxyphenyl)‐iminomethylphenol) were used to study their antioxidant and cytotoxic activity. Novel , n − 3, 2) Schiff synthesized characterized by H, 13 C NMR, IR elemental analysis. The crystal structures compounds...
A series of 73 ligands and their Cu+2 Cu+1 copper complexes with different geometries, oxidation states the metal, redox activities were synthesized characterized. The aim study was to establish structure–activity relationship within a analogues substituents at N(3) position, which govern potentials Cu+2/Cu+1 couples, ROS generation ability, intracellular accumulation. Possible cytotoxicity mechanisms, such as DNA damage, intercalation, telomerase inhibition, apoptosis induction, have been...
Three pyrrolidine-derived phenanthroline diamides were studied as ligands for lutetium trinitrate. The structural features of the complexes have been using various spectral methods and X-ray. presence halogen atoms in structure has a significant impact on both coordination number solvate water molecules internal sphere. stability constants with La(NO3)3, Nd(NO3)3, Eu(NO3)3, Lu(NO3)3 measured to demonstrate higher efficiency fluorinated ligands. NMR titration was performed this ligand, it...
A synthesis route to rock salt zinc oxide (rs-ZnO), high-pressure phase metastable at ambient conditions, has been developed. High-purity bulk nanocrystalline rs-ZnO synthesized from wurtzite (w) ZnO nanopowders 7.7 GPa and 770–820 K and, for the first time, recovered normal conditions. Structure, composition, thermal stability of have studied by synchrotron X-ray powder diffraction absorption spectroscopy (XANES EXAFS) pressure. Phase purity was achieved usage w-ZnO nanoparticles with a...
The first example of glycine catalyzed directly synthesis 6-imino-2,7-dioxabicyclo[3.2.1]octane-4,4,5-tricarbonitriles in aqueous medium was described, giving products excellent yields and up to diastereoselectivities.
The synthesis and in vitro cytotoxicity of a series Pt IV complexes with lonidamine as ligand coordinated axial position are described. Lonidamine was found to affect strongly the cytotoxic activity these new complexes, lowering IC 50 values down nanomolar range. Lipophilicity assessed terms log P showed no direct correlation cytotoxicity.
The fact of the fracture extraction curve lanthanides by 1,10-phenanthroline-2,9-diamides is explained in terms structure complexes, solvent data and quantum chemical calculations. proceeds two competing directions: form neutral complexes LLn(NO3)3 tight ion pairs {[LLn(NO3)2 H2O]+ (NO3−).
Novel variously substituted thiohydantoin-based dispiro-indolinones were prepared using a regio- and diastereoselective synthetic route from 5-arylidene-2-thiohydantoins, isatines, sarcosine. The obtained molecules subsequently evaluated in vitro against the cancer cell lines LNCaP, PC3, HCTwt, HCT(-/-). Several compounds demonstrated relatively high cytotoxic activity vs. LNCaP cells (IC50 = 1.2-3.5 µM) reasonable selectivity index (SI 3-10). Confocal microscopy revealed that conjugate of...
Novel hydantion and thiohydantoin-based spiro-compounds were prepared via theDiels–Alder reactions between 5-methylidene-hydantoins or 5-methylidene-2-thiohydantoins 1,3-dienes (cyclopentadiene, cyclohexadiene, 2,3-dimethylbutadiene, isoprene). It was shown that the cycloaddition proceed regioselectively stereoselectively with formation of exo-isomers in cyclic dienes andthe less sterically hindered products isoprene. Reactions methylideneimidazolones cyclopentadiene viaco-heating reactants;...
An easy synthesis of novel highly functionalized 5,6-dihydroindolo[2,1-a]isoquinolines was developed via a pseudo four-component domino reaction 1-aroyl-3,4-dihydroisoquinolines, terminal α,β-ynones, and malononitrile. The selective formation this biologically relevant heterocyclic core achieved using one-pot approach under microwave irradiation. the same skeleton through 5,6-dihydropyrrolo[2,1-a]isoquinolines with malonic acid dinitrile supports proposed mechanism, involving intermediate...
The parameters of stability, guest binding reversibility, and Gibbs energy inclusion were determined for clathrates adamantylcalix[4]arene (1). These data provide a new insight into the structure-property relationships in vapor sensor applications clathrate-forming hosts. A thin layer 1, used quartz microbalance (QCM) sensor, demonstrates selectivity organic vapors, which depends on regeneration technique after binding. Complete 1 surface was reached through exchange bound with ethanol...
The syntheses of novel Pd complexes with germylene and stannylene ligands are reported. [MeN(CH2CH2NC6F5)2Sn]4Pd (2) [MeN(CH2CPh2O)(CH2CH2O)Ge]4Pd (8) were obtained by different methods including ligand substitution in (Ph3P)4Pd or the reaction free corresponding (Ph3P)2PdCl2 Pd(OAc)2. Crystal structures 2, 8 determined single crystal X-ray diffraction analysis. catalytic activity was examined Suzuki-Miyaura Heck cross-coupling.
Abstract The reaction of β,δ‐triketones with an ethereal solution H 2 O catalyzed by heteropoly acids in the presence a polar aprotic co‐solvent proceeds via three pathways to form classes peroxides: tricyclic monoperoxides, bridged tetraoxanes, and pair stereoisomeric ozonides. is unusual that produces tetraoxanes ozonides one carbonyl groups remaining intact. In synthesis peroxide ring formed hydrogen two at β positions. from ketones unique process which ozonide participation δ...
Two series of germanium compounds, (p-Tol)3Ge-MMe3 (M = Si (1), Ge (2), Sn (3)) and (Me3Si)3Ge-MPh3 (4), (5)), were prepared using lithium or potassium intermediates. The changing the reaction conditions results in trigermane Ph3Ge-Ge(SiMe3)2-GePh3 (6). molecular structures 1, 2, 6 investigated by X-ray analysis. By UV/visible spectroscopy it is established that introduction a tin atom significant bathochromic absorption shift. Furthermore, according to cyclic voltammetry, oxidation...
A series of substituted pyridine dialcohols (2,6-bis(hydroxyalkyl)pyridines), 1-4, was used for the synthesis various types aluminum complexes. Aluminum methyl derivatives, 2-4a, were obtained by reaction AlMe3 with corresponding ligand or transmetallation reactions germylenes. chloride complexes, 3-4b, substitution Me group under action chlorinating agents. Methoxy-, 2-4c, benzyloxy-, 2d, complexes synthesized in transalkoxylation Me2Al(OX) (X = Me, Bn) ligand. All thoroughly investigated...
Several novel aryl substituted 2-halogencinchomeronic dinitriles, possessing an intensive solid state fluorescence, were synthesized. The relationship between the chemical structures and photophysical properties of these compounds was investigated.
A series of germanes Ar3GeX, containing electron-withdrawing substituents [Ar = p-FC6H4, 1a–d, 1a (X Cl), 1b Br), 1c H), 1d NMe2); p-F3CC6H4, 2a–d, 2a 2b 2c 2d NMe2)], was synthesized and used to prepare symmetrical digermanes Ar3Ge–GeAr3, (p-FC6H4)3GeGe(C6H4F-p)3 (3), (p-F3CC6H4)3GeGe(C6H4CF3-p)3 (4) trigermane [(p-F3CC6H4)3Ge]2Ge(C6F5)2 (5) by hydrogermolysis reaction. The properties all compounds were investigated multinuclear NMR for oligogermanes UV/vis fluorescence spectroscopy, as...
Heating Pd/NHC complexes with aliphatic amines induces Pd–NHC bond cleavage, while treating the primary or secondary in presence of strong bases promotes activation molecular catalysis.