A5000669074- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Advanced Sensor and Energy Harvesting Materials
- Hydrogels: synthesis, properties, applications
- Conducting polymers and applications
- Cellular Mechanics and Interactions
- Silk-based biomaterials and applications
- Bone Tissue Engineering Materials
- Acoustic Wave Resonator Technologies
- Biochemical and Structural Characterization
- Synthetic Organic Chemistry Methods
- Analytical Chemistry and Sensors
- Transgenic Plants and Applications
- Reconstructive Surgery and Microvascular Techniques
- Click Chemistry and Applications
- Mesenchymal stem cell research
- Transition Metal Oxide Nanomaterials
- Quantum Dots Synthesis And Properties
- Nanoplatforms for cancer theranostics
- Thermal Radiation and Cooling Technologies
- Neuroscience and Neural Engineering
- Chemical Synthesis and Analysis
- Supercapacitor Materials and Fabrication
- Advanced Thermoelectric Materials and Devices
Ulsan National Institute of Science and Technology
2020-2025
Harvard University
2024-2025
Brigham and Women's Hospital
2024-2025
Medizinische Hochschule Hannover
2004
Abstract Bioelectronic implants delivering electrical stimulation offer an attractive alternative to traditional pharmaceuticals in electrotherapy. However, achieving simple, rapid, and cost‐effective personalization of these for customized treatment unique clinical physical scenarios presents a substantial challenge. This challenge is further compounded by the need ensure safety minimal invasiveness, requiring essential attributes such as flexibility, biocompatibility, lightness,...
Abstract Multiscale polymer engineering, involving chemical modification to control their triboelectric polarities as well physicomechanical maximize charge transfer and structural durability, is paramount developing a high‐performance nanogenerator (TENG). This report introduces highly efficient comprehensive strategy engineer TENG based on multifunctional polysuccinimide (PSI). With the ability of PSI undergo facile nucleophilic addition with amines, sodium sulfate quaternary ammonium...
Abstract Generating functional and perfusable micro-vascular networks is an important goal for the fabrication of large three-dimensional tissues. Up to now, a complicated multitask involving several different factors such as time consuming, cells survival, micro-diameter vasculature strict alignment. Here, we propose technique combining multi-material extrusion ultrasound standing wave forces create network structure human umbilical vein endothelial within mixture calcium alginate...
The increasing demand for energy autonomy in microscale and wearable electronics has intensified research interest thermoelectric thin-film-based power generators. However, the development of such devices is challenging due to intrinsic brittleness inorganic materials poor performance thin films. Recently, Ag2S-based compounds have emerged as ductile semiconductors. Nonetheless, their films remains constrained, especially at low temperatures. Herein, we present a solution-processed...
One of the most promising techniques for treating severe peripheral artery disease is use cellular tissue-engineered vascular grafts (TEVGs). This study proposes an inverse-gravity (IG) extrusion technique creating long double-layered TEVGs with diameters over 3 mm. A three-layered coaxial laminar hydrogel flow in 8 mm-diameter pipe was realised simply by changing direction from being aligned gravity to against it. produced extruded mixture human aortic smooth muscle cells (HASMCs) and...
Fibrosis is one of the most frequent occurrences during one's lifetime, identified by various physiological changes including, notably, excessive deposition extracellular matrix (ECM). Despite its importance, it still a significant challenge to conduct systematic investigation tissue fibrosis, mainly due lack in vitro 3D model that can accurately portray characteristic features fibrotic events. Herein, hybrid hydrogel system incorporating dispersible nanofibers developed emulate highly...
Microporous hydrogels have been widely used for delivering therapeutic cells. However, several critical issues, such as the lack of control over harsh environment they are subjected to under pathological conditions and rapid egression cells from hydrogels, produced limited outcomes. To address these challenges, cell-tethering hypoxic conditioning colloidal containing mesenchymal stem (MSCs) introduced increase productivity paracrine factors locally in a long-term manner. Cell-tethering that...
Abstract Myocardial infarction (MI) is a significant cardiovascular disease that restricts blood flow, resulting in massive cell death and leading to stiff noncontractile fibrotic scar tissue formation. Recently, sustained oxygen release the MI area has shown regeneration ability; however, improving its therapeutic efficiency for regenerative medicine remains challenging. Here, combinatorial strategy cardiac repair by developing cardioprotective oxygenating hybrid hydrogels locally sustain...
Fragestellung: Die Rekonstruktion von Sehnengewebe stellt oftmals ein chirurgisches Problem dar. Stark destruiertes Gewebe kann häufig nicht primär genäht, sondern muss durch aufwändige Sehnentransplantationen oder -transpositionen rekonstruiert werden. Hierfür müssen selten intakte Sehnen funktionell wichtige motorische Einheiten verwendet In der vorliegenden Studie sollte untersucht werden, ob sich langstreckige sehnenähnliche Konstrukte in vitro aus humanen mesenchymalen Stammzellen (MSZ)...
In order to manipulate the complex behavior of cells in a 3-dimensional (3D) environment, it is important provide microenvironment that can accurately portray complexity highly anisotropic tissue structures. However, technically challenging generate using conventional biomaterials are mostly isotropic with limited bioactivity. this study, gelatin-hyaluronic acid hydrogel incorporated aqueous-dispersible, short nanofibers capable situ alignment developed emulate native heterogeneous...
Silk-Based Hydrogels In article number 2312261, Su Ryon Shin and co-workers present that the local delivery of oxygen a chemoattractant stem cells via injectable, mechanically robust, tissue-adhesive silk-based hybrid hydrogels alleviated ischemia induced host cell homing at myocardial infarction area, leading to decreased fibrotic scar formation improved cardiac functional recovery.