A5017691291- Palliative Care and End-of-Life Issues
- Bioinformatics and Genomic Networks
- Mechanical Circulatory Support Devices
- Geriatric Care and Nursing Homes
- Family Support in Illness
- Gene expression and cancer classification
- Health, psychology, and well-being
- melanin and skin pigmentation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Family and Patient Care in Intensive Care Units
- Liver Disease and Transplantation
- RNA modifications and cancer
- Renal Transplantation Outcomes and Treatments
- Cancer-related molecular mechanisms research
- Cancer survivorship and care
- Heart Failure Treatment and Management
- Adolescent and Pediatric Healthcare
- RNA Research and Splicing
- Renal and Vascular Pathologies
- Health and Wellbeing Research
- Family and Disability Support Research
- Cardiac Arrest and Resuscitation
- Dialysis and Renal Disease Management
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
Zhejiang University
2020-2024
Huazhong Agricultural University
2024
First Affiliated Hospital of Jiangxi Medical College
2024
Nanchang University
2024
Institute of Biomedical Sciences, Academia Sinica
2024
Chang Gung University
2013-2022
Chang Gung Memorial Hospital
2006-2022
Taoyuan Chang Gung Memorial Hospital
2021-2022
Linkou Chang Gung Memorial Hospital
2022
Sir Run Run Shaw Hospital
2020
Abstract Background RNA pseudouridylation is a critical post‐transcriptional modification that influences gene expression and impacts various biological functions. Despite its significance, the role of mRNA in cancer remains poorly understood. This study investigates impact pseudouridine synthase 7 (PUS7)‐mediated Alpha‐ketoglutarate‐dependent Dioxygenase alkB Homolog 3 ( ALKBH3 ) gastric cancer. Methods Immunohistochemistry Western blotting were used to assess PUS7 protein levels human...
Esophagitis is the second most common gastrointestinal manifestation of cytomegalovirus (CMV) infection after colitis. CMV esophagitis has been reported in patients who have undergone transplantation, are on long-term renal dialysis, or human immunodeficiency virus infection. This study aimed to investigate clinical characteristics and manifestations underwent diagnostic endoscopy. A total 16 with histologically proven were identified from 1539 esophageal ulcers analyzed retrospectively...
Abstract Paddy fields are hotspots of microbial denitrification, which is typically linked to the oxidation electron donors such as methane (CH 4 ) under anoxic and hypoxic conditions. While several anaerobic methanotrophs can facilitate denitrification intracellularly, whether how aerobic CH couples with in paddy remains virtually unknown. Here we combine a ~3300 km field study across main rice-producing areas China 13 -DNA-stable isotope probing (SIP) experiments investigate role soil...
This paper is a report of study to explore the self-management behaviours patients with chronic obstructive pulmonary disease (COPD).Chronic major cause morbidity and mortality throughout world. A patient-centred perspective calls for investigation as means develop programmes enhance quality life COPD.The participants were convenience sample 18 COPD various severities. Interview data collected in thoracic ward, outpatient department rehabilitation unit medical centre Taiwan from November...
The aim of this study is to quantify the amount and causes stress in renal transplant recipients.After transplantation, patients may encounter physical psychosocial problems. Through patient collaboration with healthcare professionals, treatment after transplantation aimed at restoring maintaining a 'normal' life. To achieve quality life, research needs recipients, from patient-centred perspective.A cross-sectional, descriptive study.The was conducted outpatient department medical centre...
Colorectal cancer (CRC) is one of the leading cancers worldwide. Several studies have performed microarray data analyses for classification and prognostic analyses. Microarray assays also enable identification gene signatures molecular characterization treatment prediction.Microarray expression from online Gene Expression Omnibus (GEO) database were used to distinguish colorectal normal colon tissue samples.We collected GEO establish datasets a combined analysis. Using Prediction Analysis...
Although the genetic basis of androgenic alopecia has been clearly established, little is known about its non-genetic causes, such as environmental and lifestyle factors.This study investigated blood urine heavy metals concentrations, exposure factors, personal behaviors, dietary intakes genotypes related susceptibility genes in patients with (AGA).Age, AGA level, residence area, work hours, sleep patterns, cigarette usage, alcohol consumption, betel nut hair treatments, eating habits, body...
Background: Empowering personal health records (PHRs) provides basic human right, awareness, and intention for promotion. As care delivery changes toward patient-centered services, PHRs become an indispensable platform consumers providers. Recently, the government introduced "My bank," a Web-based electronic medical (EMRs) repository consumers. However, it is not yet PHR. To date, we do have that can let patients manage their own Objective: This study creates vision of value-added data...
Disease self-management for patients with chronic obstructive pulmonary disease (COPD) is less well characterized than that other diseases. A patient-centered perspective calls qualitative research to investigate the process of as a means enhancing quality life in COPD.This study explores COPD and factors impact efficacy this process.A inquiry approach was used collect data thoracic ward, outpatient department, respiratory therapy room medical center Taiwan. convenience sample 19 collected....
Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy is the primary treatment option for patients with non-small cell lung cancer (NSCLC). However, one of major adverse effects associated this skin toxicity, which impacts patient's quality life. This study aimed to describe severities and locations analyze their association life in advanced NSCLC who received EGFR-TKI as first-line treatment.This cross-sectional correlation was conducted at a tertiary medical center...
Neck circumference (NC) is an anthropometric measure of obesity for upper subcutaneous adipose tissue distribution which associated with cardiometabolic risk. This study investigated whether NC indicators chronic kidney disease (CKD) high risk patients.A total 177 consecutive patients who underwent the outpatient departments cardiology were prospectively enrolled in study. The aged >20 years normal renal function or stages 1-4 CKD. A linear regression was performed using Enter method to...
ABSTRACT Background: Factors affecting quality of life (QOL) ratings for people with dementia (PWD) have been well studied, but few studies examined the effect residence on PWD- and caregiver-rated QOL PWDs. We designed this study to determine factors related in as discrepancy these ratings. Methods: For cross-sectional study, we analyzed data from a convenience sample 106 PWD-family caregiver dyads (58 community-dwelling 48 nursing-home dyads). PWDs’ included socio-demographic variables,...
Few studies have evaluated completely the changes in quality of life (QOL) that occur from pretreatment through first four consecutive cycles chemotherapy or determined its determinants patients with advanced non-small-cell lung cancer (NSCLC).The aim this study was to explore and QOL NSCLC under initial Cycle 4 chemotherapy.The 139 assessed prechemotherapy chemotherapy. Changes were using multivariate linear regression, which used generalized estimation equation models.No significant...
Patients with metastatic gastric cancer (GC) have a poor prognosis; however, the molecular mechanism of GC metastasis remains unclear. Here, we employed bioinformatics to systematically screen metastasis-associated genes and found that levels basal cell adhesion molecule (BCAM) were significantly increased in tissues from patients metastasis, as compared those without metastasis. The upregulation BCAM was also associated shorter survival time. Depletion inhibited migration invasion. Knockout...
The population of elderly patients entering chronic dialysis programmes is increasing. Elderly are susceptible to malnutrition and have multiple complicating disorders in addition uraemia. Selecting appropriate modality particularly critical patients. Continuous ambulatory peritoneal (CAPD) has many advantages patients; however, the clinical outcome varies for CAPD In comparison with Westerners, Southeast Asians a small body mass index may be more suited therapy. To identify prognostic...
To examine the effect of self-efficacy, subjective work ability, depression and symptom distress on to provide a description of, employment leisure activities liver transplant recipients.Return have become an important aspect life for recipients worldwide. An investigation factors that influence status has been recommended as means help restore their productivity.This was cross-sectional, descriptive correlational study in 2010.A convenience sampling method used. Data were collected using...
Background Extracorporeal life support (ECLS) provides emergency pulmonary and cardiac assistance for patients in respiratory or failure. Most studies evaluate the success of ECLS based on patients' survival rate. However, trajectory health status quality (QOL) should also be important considerations. The study's aim was to explore changes QOL adult weaned from who survived hospital discharge over a one-year period. Study design A prospective longitudinal study conducted April 2012 September...