Alexandra Roldan

ORCID: 0000-0001-9905-3943
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About
Contact & Profiles
Research Areas
  • Schizophrenia research and treatment
  • Bipolar Disorder and Treatment
  • Mental Health Research Topics
  • Digital Mental Health Interventions
  • Adolescent and Pediatric Healthcare
  • Parkinson's Disease Mechanisms and Treatments
  • Genetic Neurodegenerative Diseases
  • Neurological disorders and treatments
  • Epigenetics and DNA Methylation
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Centro de Investigación Biomédica en Red de Salud Mental
2022-2025

Hospital de Sant Pau
2022-2025

Instituto de Salud Carlos III
2025

Universitat Autònoma de Barcelona
2022-2023

Abstract Background Obstetric complications (OCs) are key contributors to psychosis risk. However, it is unclear whether they increase vulnerability independently of genetic risk, in interaction with it, or a manifestation proneness. We examined the role distinct types OCs terms risk and tested interact differently vulnerability, whilst accounting for other known environmental factors. Study Design 405 participants (219 first episode patients 186 healthy volunteers) underwent comprehensive...

10.1111/acps.13546 article EN cc-by Acta Psychiatrica Scandinavica 2023-03-13

ABSTRACT Background Studies have shown associations between polygenic risk scores for educational attainment (PRS EA ), cognitive reserve (CR), cognition, negative symptoms (NS), and psychosocial functioning in first‐episode psychosis (FEP). However, their specific interactions remain unclear. This study aimed to investigate the mediating roles of CR, NS relationship PRS one year after a FEP. Additionally, we sought explore impact two subtypes on this relationship: diminished Expression...

10.1111/acps.13779 article EN cc-by-nc-nd Acta Psychiatrica Scandinavica 2024-12-25

<sec> <title>BACKGROUND</title> Treatment-resistant schizophrenia (TRS) is a severe form of associated with low adherence to treatment and poor outcomes. Mobile health (mHealth) interventions may be effective in preventing relapses, increasing adherence, managing some the symptoms schizophrenia. therapeutic attention for treatment-resistant (m-RESIST) an innovative mobile solution based on novel technology offering high modular flexible functioning developed specifically TRS. To our best...

10.2196/preprints.67659 preprint EN 2024-10-17
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