A5010273880- Meta-analysis and systematic reviews
- Ethics in Clinical Research
- Mental Health and Patient Involvement
- Health Systems, Economic Evaluations, Quality of Life
- Machine Learning and Data Classification
- Health Sciences Research and Education
- Neural dynamics and brain function
- Scientific Computing and Data Management
- Health and Medical Research Impacts
- Biomedical Ethics and Regulation
- Research Data Management Practices
- Delphi Technique in Research
- Edible Oils Quality and Analysis
- Hearing, Cochlea, Tinnitus, Genetics
- Big Data and Business Intelligence
- Circadian rhythm and melatonin
- scientometrics and bibliometrics research
- Semantic Web and Ontologies
- Artificial Intelligence in Healthcare
- Patient-Provider Communication in Healthcare
- melanin and skin pigmentation
- Biochemical Analysis and Sensing Techniques
- Health and Medical Studies
- Neuroscience and Music Perception
- Patient Satisfaction in Healthcare
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2020-2025
Charité - Universitätsmedizin Berlin
2021-2024
University Hospital of Basel
2022
University of Basel
2022
Ludwig-Maximilians-Universität München
2014-2020
Institute of Neurobiology
2020
The state of open science needs to be monitored track changes over time and identify areas create interventions drive improvements. In order monitor practices, they first need well defined operationalized. To reach consensus on what practices at biomedical research institutions, we conducted a modified 3-round Delphi study. Participants were administrators, researchers, specialists in dedicated roles, librarians. rounds 1 2, participants completed an online survey evaluating set potential...
Objectives To evaluate the extent and quality of patient involvement reporting in examples current practice health research. Design Mixed-methods study. We used a targeted search strategy across three cohorts to identify research publications that reported involvement: original articles published 2019 British Medical Journal (BMJ), listed Patient-Centered Outcomes Research Institute (PCORI) database (2019), citing GRIPP2 (Guidance for Reporting Involvement Patients Public) checklist or...
Passive and active membrane properties determine the voltage responses of neurons. Within auditory brain stem, refinements in these intrinsic during late postnatal development usually generate short integration times precise action-potential generation. This developmentally acquired temporal precision is crucial for signal processing. How interactions develop concert to enable neurons transfer information with high has not yet been elucidated detail. Here, we show how developmental...
To systematically evaluate timely reporting of clinical trial results at medical universities and university hospitals in the Nordic countries. In this cross-sectional study, we included trials (regardless intervention) registered European Union (EU) Clinical Trials Registry and/or ClinicalTrials.gov, completed 2016-2019 led by a with faculty or hospital Denmark, Finland, Iceland, Norway, Sweden. We identified summary posted registries conducted systematic manual searches for publications...
Abstract Background Research transparency is crucial for ensuring the relevance, integrity, and reliability of scientific findings. However, previous work indicates room improvement across practices. The primary objective this study was to develop an extensible tool provide individualized feedback guidance improved phases a study. Our secondary assess feasibility implementing improve in clinical trials. Methods We developed study-level “report cards” that combine tailored investigators...
Background: Identifying and monitoring clinical trials is crucial for responsible research systems relevant to all stakeholders in research. Trial registries support accountability transparency by providing a publicly available rich source of information on trials. Cross-registration, where the same trial registered more than one registry, can complicate efforts study enterprise. Duplicate entries may need be de-duplicated or merged, discrepancies across registrations affect conclusions...
Background: Public information on US clinical trials is shared through the ClinicalTrials.gov registry. This study's goal was to determine prospective registration, results reporting, trial registration number and publication accessibility status for with primary completion dates from 2014 2017 affiliated seven California universities. Methods: We identified investigators, sponsors, or responsible parties universities searched their publications manually. then used semi-automatic methods...
Background University Medical Centers (UMCs) must do their part for clinical trial transparency by fostering practices such as prospective registration, timely results reporting, and open access. However, research institutions are often unaware of performance on these practices. Baseline assessments would highlight where there is room change empower UMCs to support improvement. We performed a status quo analysis established registration reporting at German developed dashboard communicate...
The development of sensory circuits is partially guided by experience. In the medial superior olive (MSO), these refinements generate precise coincidence detection to localize sounds in azimuthal plane. Glycinergic inhibitory inputs MSO, which tune sensitivity interaural time differences, undergo substantial structural and functional after hearing onset. Whether excitation calcium signaling MSO are similarly affected onset acoustic experience unresolved. To assess window mechanism excitatory...
While open access (OA) is growing, many publications remain behind a paywall. This limits the impact of research and entrenches global inequalities by restricting to knowledge those that can afford it. Many journal policies allow researchers make version their publication openly accessible through self-archiving in repository, sometimes after an embargo period (green OA). Unpaywall Shareyourpaper are tools help users find OA articles support authors legally self-archive papers, respectively....
Abstract Objective To systematically evaluate timely reporting of clinical trial results at medical universities and university hospitals in the Nordic countries. Study Design Setting In this cross-sectional study, we included trials (regardless intervention) registered EU Clinical Trials Registry and/or ClinicalTrials.gov, completed 2016-2019, led by a with faculty or hospital Denmark, Finland, Iceland, Norway, Sweden. We identified summary posted registries, conducted systematic manual...
Abstract Background Mandates and recommendations related to embedding open science practices within the research lifecycle are increasingly common. Few stakeholders, however, monitoring compliance their mandates or recommendations. It is necessary monitor current state of track changes over time identify areas create interventions drive improvements. Monitoring requires that they defined operationalized. Involving biomedical community, we sought reach consensus on a core set at institutions....
Abstract While Open Access (OA) is growing, many publications remain behind a paywall. This limits the impact of research and entrenches global inequalities by restricting access to knowledge those that can afford it. Many journal policies allow researchers make version their publication openly accessible through self-archiving in repository, sometimes after an embargo period (green OA). Unpaywall Shareyourpaper are open tools help users find OA articles support authors legally self-archive...
ABSTRACT Research transparency is crucial for ensuring the relevance, integrity, and reliability of scientific findings. However, previous work indicates room improvement across practices. The primary objective this study was to develop an extensible tool provide individualized feedback guidance improved phases a study. Our secondary assess feasibility implementing improve in clinical trials. We developed study-level “report cards” that combine tailored investigators several practices,...
The scholarly publishing system is adapting to many changes including open access and data mandates, new technologies, artificial intelligence. Members of the research communities are working establish a more equitable, fair, rigorous that serves researchers’ evolving needs. Early career researchers (ECRs) drivers change, publishers may wonder why how they should involve ECRs in shaping future publishing. We held virtual unconference explore this issue with who were improve Some participants...
Background. While there is evidence that open access (OA) has been growing (Hobert et al., 2021; Piwowar 2018), many publications remain behind a paywall. In cases, journal or publisher self-archiving policies allow researchers to make version of their publication openly accessible in repository, sometimes after an embargo period (green OA). The UNESCO Recommendation on Open Science (UNESCO, 2021) adopted November 2021 recommends several priority areas action, including fostering culture...
ABSTRACT Objectives To evaluate the extent and quality of patient involvement reporting in examples current practice health research. Design Mixed-methods study. We used a targeted search strategy across three cohorts to identify research publications that reported involvement: published The BMJ , listed PCORI database, citing GRIPP2 checklist for or critical appraisal guideline user involvement. Publications were coded according coding schemes: “Phase involvement”, GRIPP2-SF checklist,...