A5064796863- Mechanical Circulatory Support Devices
- Organ Transplantation Techniques and Outcomes
- Nosocomial Infections in ICU
- Antibiotics Pharmacokinetics and Efficacy
- Liver Disease and Transplantation
- Intensive Care Unit Cognitive Disorders
- Pneumonia and Respiratory Infections
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Ultrasound in Clinical Applications
- Respiratory Support and Mechanisms
- Hepatocellular Carcinoma Treatment and Prognosis
- Venous Thromboembolism Diagnosis and Management
- Congenital Diaphragmatic Hernia Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Muscle and Compartmental Disorders
- Liver physiology and pathology
- S100 Proteins and Annexins
- Inhalation and Respiratory Drug Delivery
- Abdominal Trauma and Injuries
- Amoebic Infections and Treatments
- Pneumothorax, Barotrauma, Emphysema
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
Sorbonne Université
2016-2024
Pitié-Salpêtrière Hospital
2016-2024
Assistance Publique – Hôpitaux de Paris
2016-2024
Groupe de recherche clinique en anesthésie réanimation médecine périopératoire
2021-2022
Institut Pasteur
2018-2020
Unité de recherche sur les maladies cardiovasculaires et métaboliques
2019
Sorbonne Paris Cité
2019
Fondation pour l’innovation en Cadiométabolisme et Nutrition
2019
Hôpital Charles-Foix
2017
Imation (United States)
2016
Abstract Background Nebulisation of antibiotics is a promising treatment for ventilator-associated pneumonia (VAP) caused by multidrug-resistant organisms. Ensuring effective antibiotic concentrations at the site infection in interstitial space fluid crucial clinical outcomes. Current assessment methods, such as epithelial lining and tissue homogenates, have limitations providing longitudinal pharmacokinetic data. Main body Lung microdialysis, an invasive research technique predominantly...
Objectives: Postcardiotomy cardiogenic shock occurs in 2–6% of patients undergoing cardiac surgery, and 1% surgery will require mechanical circulatory support using venoarterial extracorporeal membrane oxygenation. Acute kidney injury is a frequent complication this population negatively impacts the survival. We aimed to determine whether timing oxygenation implantation influences renal prognosis these patients. Design: Retrospective observational cohort study between January 2013 December...
Hospital-acquired pneumonia (HAP) is the most common and severe complication in patients treated with venoarterial extracorporeal membrane oxygenation (VA ECMO) its diagnosis remains challenging. Nothing known about usefulness of lung ultrasound (LUS) early detection HAP VA ECMO. Also, LUS chest radiography were performed when was suspected cardiac critically ill adult ECMO presenting acute respiratory failure. The sonographic features determined we assessed performance simplified clinical...
Postoperative operative pulmonary complications (PPCs) after hepatic surgery are associated with increased length of hospital stays. Intraoperative blood transfusion, extensive resection and different comorbidities have been identified. Other parameters, like time ischemia, neither clinically studied, though experimental studies show that ischemia can provide lung injury. The objective this study was to determinate the risk factors postoperative within 7 days. Ninety-four patients...
Abstract Postoperative cognitive dysfunction (POCD) is a major complication affecting patients of any age undergoing surgery. This syndrome impacts everyday life up to months after hospital discharge, and its pathophysiology still remains unclear. Translational research focusing on POCD based wide variety rodent models, such as the murine tibial fracture, whose severity can limit mouse locomotion proper behavioral assessment. Besides, influence skeletal muscle injury, lesion encountered in...
Innovative advances in the immunologic understanding of relative resistance transplanted liver to rejection have continuously performed past decade as results experimental and clinical studies. Whereas mechanisms tolerogenic role were underlined, many evidences appeared that antibody mediated (AMR) was probably not so negligible we historically thought transplantation (LT). This review will address spectrum mechanism cellular humoral rejection, tolerance, specific properties liver,...
Abstract BACKGROUND : Hospital-Acquired Pneumonia (HAP) is the most common and severe complication in patients treated with veno-arterial extracorporeal membrane oxygenation (ECMO). HAP early detection challenging but crucial for improving clinical outcomes. We conduct an observational study to assess whether Lung Ultrasound (LUS) improves of ECMO.METHODS: conducted a single-center, prospective, including adult receiving assistance that presented acute respiratory failure. Bedside LUS chest...