A5051729464- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Thyroid Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Nematode management and characterization studies
- Neuroendocrine Tumor Research Advances
- Thyroid and Parathyroid Surgery
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Gastrointestinal Tumor Research and Treatment
- Liver Disease Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Genomics and Diagnostics
- Intraperitoneal and Appendiceal Malignancies
- Legume Nitrogen Fixing Symbiosis
- Enhanced Recovery After Surgery
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Radiomics and Machine Learning in Medical Imaging
- Pituitary Gland Disorders and Treatments
University of California, San Francisco
2021-2025
Women's College Hospital
2023-2025
University of Toronto
2023-2025
Cairo University
2014-2025
Sokoine University of Agriculture
2025
Hôpital Edouard Herriot
2024
Ted Rogers Centre for Heart Research
2024
University Health Network
2024
University of Tripoli
2024
UCSF Helen Diller Family Comprehensive Cancer Center
2024
To examine the association between extent of surgery and overall survival in a large contemporary cohort patients with papillary thyroid cancer (PTC).Guidelines recommend total thyroidectomy for PTC tumors >1 cm, based on older data demonstrating an advantage over lobectomy.Adult 1.0-4.0 cm undergoing National Cancer Database, 1998-2006, were included. Cox proportional hazards models applied to measure while adjusting patient demographic clinical factors, including comorbidities,...
To determine the number of total thyroidectomies per surgeon year associated with lowest risk complications.The volume-outcome association has been established for thyroidectomy; however, a threshold cases defining "high-volume" remains unclear.Adults undergoing thyroidectomy were identified from Health Care Utilization Project-National Inpatient Sample (1998-2009). Multivariate logistic regression restricted cubic splines was utilized to examine between annual and complications.Among 16,954...
Cervical lymph node metastases are recognized as a prognostic indicator only in patients age 45 years or older with papillary thyroid cancer (PTC); younger than perceived to have low-risk disease. The current American Joint Committee on Cancer staging for PTC does not include cervical metastases. Our objective was test the hypothesis that presence and number of an adverse impact overall survival (OS) PTC.Adult undergoing surgery stage I (no distant metastases) were identified from National...
To describe national practice patterns regarding utilization of minimally invasive pancreaticoduodenectomy (MIPD) and compare short-term outcomes with those following open for cancer.There is increasing interest in use MIPD; however, published data are limited to single institutional experiences.Adult patients undergoing were identified from the National Cancer Database, 2010-2011. Descriptive statistics multivariable modeling employed characterize MIPD (laparoscopic or robotic)...
Colorectal cancer (CRC) is the fourth most frequently diagnosed and second leading cause of death in United States. Management disseminated metastatic CRC involves various active drugs, either combination or as single agents. The choice therapy based on consideration goals therapy, type timing prior mutational profile tumor, differing toxicity profiles constituent drugs. This manuscript summarizes data supporting systemic options recommended for NCCN Guidelines Colon Cancer.
The determination of an optimal treatment plan for individual patient with rectal cancer is a complex process. In addition to decisions relating the intent surgery (ie, curative or palliative), consideration must also be given likely functional results treatment, including probability maintaining restoring normal bowel function/anal continence and preserving genitourinary functions. Particularly patients distal cancer, finding balance between curative-intent therapy while having minimal...
A molecular protocol is presented for distinguishing seven of the most common and economically important Meloidogyne spp. DNA was extracted from individual second‐stage juvenile (J2) nematodes amplified by PCR (polymerase chain reaction). Fifteen PCRs including amplification rDNA, specific SCAR (sequence characterized region) RAPD (random polymorphic DNA) fragments were possible DNA. This enabled a diagnostic key M. incognita , javanica arenaria mayaguensis hapla chitwoodi fallax to be...
This study compares outcomes following pancreaticoduodenectomy (PD) for patients treated at local, low-volume centers and those traveling to high-volume centers.Although PD are superior institutions, not all live in proximity major medical centers. Theoretical advantages undergoing surgery locally exist.The 1998 2012 National Cancer Data Base was queried T1-3N0-1M0 pancreatic adenocarcinoma who underwent PD. Travel distances treatment were calculated. Overlaying the upper lower quartiles of...
The potential of bacterial antagonists fungal pathogens to control the root-knot nematode Meloidogyne incognita was investigated under greenhouse conditions. Treatment tomato seeds with several strains significantly reduced numbers galls and egg masses compared untreated control. Best performed Bacillus subtilis isolates Sb4-23, Mc5-Re2, Mc2-Re2, which were further studied for their mode action regard direct effects by metabolites or repellents, plant mediated effects. Drenching soil culture...
Patients with thyroid cancer who have extrathyroidal extension (ETE) are considered to more advanced tumors. However, data on the impact of ETE patient outcomes remain limited. The purpose this study was evaluate association between and survival in patients cancer.The National Cancer Database (1998-2012) queried for all adult differentiated medullary cancer. were divided into three groups: no (T1 T2 tumors), minimal (T3 tumors <4 cm), extensive (T4 cm). Patient demographic, clinical,...
Purpose Patient age is considered to play a unique prognostic role in papillary thyroid cancer (PTC), with distinct staging dichotomization at 45 years of age. This based on older, limited data demonstrating marked rise mortality around the ages 40 50 years. We hypothesized that associated compromised survival from cancer, no cutoff denoting difference. Patients and Methods PTC who had surgery were identified SEER database (1998 2012). Multivariable proportional hazards modeling utilizing...
There is increasing interest in expanding use of minimally invasive pancreaticoduodenectomy (MIPD). This procedure complex, with data suggesting a significant association between hospital volume and outcomes.To determine whether there an MIPD threshold for which patient outcomes could be optimized.Adult patients undergoing were identified from the Healthcare Cost Utilization Project National Inpatient Sample 2000 to 2012. Multivariable models restricted cubic splines used identify by...
Understanding the interactions of plant-parasitic nematodes with antagonistic soil microbes could provide opportunities for novel crop protection strategies. Three arable soils were investigated their suppressiveness against root knot nematode Meloidogyne hapla. For all three soils, M. hapla developed significantly fewer galls, egg masses, and eggs on tomato plants in unsterilized than sterilized infested soil. Egg numbers reduced by up to 93%. This suggested suppression microbial...
Plant protection via disease-suppressive bacteria in desert farming requires specific biological control agents (BCAs) adapted to the unique arid conditions. We performed an ecological study of below-ground communities farm soil and untreated soil, based on these findings, selected antagonists were hierarchically evaluated. In contrast highly 16S rRNA fingerprints bacterial cultivated medicinal plants, internal transcribed spacer profiles fungal less discriminative mainly characterised by...
Malignant struma ovarii (MSO) is a germ cell tumor of the ovary histologically identical to differentiated thyroid cancers. There paucity data on this neoplasm, with fewer than 200 reported cases. The primary objective study was examine survival rate women diagnosed MSO using from Surveillance, Epidemiology, and End RESULTS (SEER) database. Secondary objectives were describe demographic, clinical, pathologic, treatment characteristics population.A retrospective analysis performed...
Papillary thyroid cancer (PTC) patients <45 years old are considered to have an excellent prognosis; however, current guidelines recommend total thyroidectomy for PTC tumors >1.0 cm, regardless of age.
It is undetermined if malignancy independently increases stroke risk in atrial fibrillation (AF). This study sought to determine the association of with and bleeding AF. Population-based cohort using administrative datasets people aged ≥66 years newly diagnosed People within 5 before AF diagnosis were matched cancer-free control subjects on age, sex, details, CHA2DS2-VASc score, ATRIA score. Outcomes included hospitalizations for hospitalization/emergency visits bleeding. Cause-specific...
Background Neoadjuvant therapy has theoretical benefits for pancreatic cancer; however, its association with perioperative outcomes remains controversial. This study sought to evaluate variation in use of neoadjuvant and following resection. Methods The National Cancer Data Base (1998‐2011) was queried patients Stage I or II adenocarcinoma who underwent pancreaticoduodenectomy. Subjects were classified by chemotherapy and/or radiation therapy. Factors associated evaluated, compared. Results...
Controversy exists around the American Joint Committee on Cancer (AJCC) TNM staging system for medullary thyroid cancer (MTC). Because of rarity disease and limited available data, MTC has been largely extrapolated from differentiated cancer.To evaluate how well current (seventh eighth editions) AJCC correlates with survival patients to suggest a possible revision.This population-based retrospective cohort analysis used National Database select aged 18 years or older diagnosed in United...
Robotic pancreatectomy is gaining momentum; however, limited data exist on the long-term survival of this approach for pancreatic ductal adenocarcinoma (PDAC). The objective study to compare oncologic outcomes robotic pancreaticoduodenectomy (RPD) and distal (RDP) open surgery in patients with PDAC.Robotic stages I-III PDAC were obtained from 2010 2016 National Cancer Database.We identified 17 831 pancreaticoduodenectomies 2718 pancreatectomies which 626 (4%) 332 (12%) robotic, respectively....