A5050482906- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Visual perception and processing mechanisms
- Retinal Diseases and Treatments
- Maritime Ports and Logistics
- Corneal Surgery and Treatments
- Ocular Infections and Treatments
- Spinal Fractures and Fixation Techniques
- Enzyme Production and Characterization
- Ergonomics and Musculoskeletal Disorders
- Seaweed-derived Bioactive Compounds
- Ophthalmology and Eye Disorders
- Scoliosis diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Tracheal and airway disorders
- Maritime Navigation and Safety
- Optical Systems and Laser Technology
- Maritime Transport Emissions and Efficiency
- Optical Coherence Tomography Applications
- Cervical and Thoracic Myelopathy
- Animal Nutrition and Health
- Pelvic floor disorders treatments
China Agricultural University
2002-2025
Chongqing Jiaotong University
2010-2025
Nanjing Drum Tower Hospital
2023-2024
Wenzhou Medical University
2015-2024
Affiliated Eye Hospital of Wenzhou Medical College
2015-2024
Soochow University
2019-2024
National Clinical Research Center for Digestive Diseases
2021-2023
First Affiliated Hospital of Soochow University
2023
Shanghai Jiao Tong University
2020
Shanghai First People's Hospital
2020
An alginate lyase (FsAly7) from
To evaluate the effect of newly designed positively aspherized progressive addition lenses (PA-PALs), which reduce both lag accommodation and hyperopic defocus on peripheral retina, progression early-onset myopia.Positively aspherized-PALs have near high positive distance zone aspherization comparable to power. One hundred ninety-seven children were enrolled, 6 12 years age, with spherical equivalent refraction from -1.00 -4.50 diopters (D). The randomized receive one three lenses: single...
Usage of different types contact lenses is associated with increased risk sight-threatening complications. Changes in the ocular microbiome caused by lens wear are suggested to affect infection development those individuals. To address this question, study compares conjunctival microbial communities wearers noncontact wearers.Paired-end sequencing V3 region 16S rRNA gene was used characterize bacterial on surfaces and nonwearers.No differences diversity were detected between nonwearers....
To investigate thickness profile changes of the corneal epithelium and Bowman's layer at vertical horizontal meridians with overnight myopia orthokeratology (OK) lenses.Twenty subjects (age range: 19-33 years) wore reverse-geometry rigid gas-permeable OK lenses in both eyes for 30 days. Before lens wear after 1, 7, days wear, evaluation fitting, visual acuity examination, topography, ultra-high resolution optical coherence tomography (UHR-OCT) were performed. The central, midperipheral,...
To investigate changes of corneal thickness at the vertical and horizontal meridians wavefront aberrations (WA) over a 30-day period overnight myopia orthokeratology (OK) lens wear.Sixteen subjects (11 women, 5 men, 26.3±3.2 years) were enrolled fitted for OK lenses. Long scan depth optical coherence tomography was used to measure profiles both baseline on days 1, 7, 30 days. Corneal ocular WA 6-mm pupil measured root-mean-square (RMS) astigmatism, coma, spherical aberration (SA), total...
To develop an automated classification system using a machine learning classifier to distinguish clinically unaffected eyes in patients with keratoconus from normal control population based on combination of Scheimpflug camera images and ultra-high-resolution optical coherence tomography (UHR-OCT) imaging data.A total 121 participants were classified by 2 cornea experts into 3 groups: (50 eyes), (38 eyes) or subclinical (33 eyes). All imaged UHR-OCT. Corneal morphological features extracted...
The study aimed to characterize the entire corneal topography and tomography for detection of sub-clinical keratoconus (KC) with a Zernike application method. Normal subjects (n = 147; 147 eyes), KC patients 77; 77 139; 139 eyes) were imaged Pentacam HR system. data pachymetry elevation both anterior posterior surfaces exported from software. polynomials fitting was used quantify 3D distribution thickness surface elevation. root mean square (RMS) values each order total high-order...
Abstract Ultra-high resolution optical coherence tomography (UHR-OCT) can image the corneal epithelium and Bowman’s layer measurement thicknesses. The purpose of this study was to validate diagnostic power vertical thickness profiles imaged by UHR-OCT in diagnosis sub-clinical keratoconus (KC). Each eye 37 KC patients, asymptomatic fellow eyes 32 patients each 81 normal subjects were enrolled. Vertical measured UHR-OCT. Diagnostic indices calculated from output values discriminant functions...
Abstract Background This study aims to examine interocular differences in the choroidal thickness and vascular density of choriocapillaris anisometropic myopes further explore relationship between blood flow myopia. Methods The sample comprised 44 participants with myopia, aged 9 18 years, normal best-corrected visual acuity. All underwent a series examinations, including spherical equivalent refraction (SER) axial length (AL), measured by Lenstar optical biometer coherence tomography...
Abstract Background Despite receiving orthokeratology (ortho-k), the efficacy of retarding ocular elongation during myopia varies among myopic children. The current study aimed to investigate early changes choroidal vasculature at one month after ortho-k treatment and its association with one-year elongation, as well role such responses in predicting control treatment. Methods A prospective cohort was conducted children treated ortho-k. Myopic aged between 8 12 years who were willing wear...
Abstract To investigate the role of tracheal wall injury in development benign airway stenosis rabbits. Prospective study. We injured walls 28 New Zealand white rabbits using four different methods. Experimental group: Group A (n = 7, mild mucosa by ordinary brush under bronchoscopy); B severe nylon tracheotomy); C cartilage was vascular clamp after D with forceps and a tracheotomy). Bronchoscopy performed on each experimental rabbit at 1, 2, 3 4 weeks operation. High-resolution computed...
Vessel traffic is an important source of global greenhouse gas emissions. The carbon emissions from ships in the canal network are directly linked to environmental performance China’s inland waterway transportation, contributing achievement reduction goals. Therefore, systematically assessing emission levels networks essential provide a robust foundation for developing more scientific and feasible strategies. To address limitations current evaluations—which often focus on single dimension...
To investigate the association between ocular sensory dominance and interocular refractive error difference (IRED).A total of 219 subjects were recruited. The errors determined by objective refraction with a fixation target located 6 meters away. 176 myopic, 83 being anisometropic (IRED ≥ 0.75 D). 43 hyperopic, 22 anisometropic. Sensory was measured continuous flashing technique tested eye viewing Gabor increasing in contrast fellow Mondrian noise decreasing contrast. log ratio to Gabor's...
This retrospective study was designed to investigate the sole influence of orthokeratology (OK) lens fitting decentration on Zernike coefficients reshaped anterior corneal surface. comprised a review 106 right eyes and measurements topography both before OK at 1-month follow-up visit. A routine calculate local surface astigmatism assist determination from pupil center. The pupil-centered baseline (PCCB) post-treatment (PCCP) were calculated. Meanwhile, OK-lens-centered (OCCP) also calculated...
To investigate choroidal thickness changes in the horizontal meridian after orthokeratology.This is a prospective cross-sectional observed study. Subjects (n=30; 11.3±1.7y) with low-to-moderate myopia (-1.0 to -6.0 diopters), wore orthokeratology (Ortho-K) lenses for 3mo. Before and Ortho-K, OCT scans were made through fovea meridian. Choroid around was acquired by custom software. The analyzed regions along divided into 7 equal zones. Ocular parameters measured Lenstar LS 900 non-contact...
Purpose. To determine age-related changes of tear menisci in healthy subjects and to compare variables between age-matched normals dry eye subjects. Methods. Anterior segment optical coherence tomography was used measure upper lower (n = 197, 8–83 years) patients 38, 19–72 years). Measured included the height area meniscus. Tear meniscus volumes were calculated based on cross-sectional areas eyelid lengths. The decrease rates also calculated. Results. There significant negative correlations...
Purpose . This retrospective study aimed at comparing the efficacy and safety of toric spherical orthokeratology lenses in treatment patients with moderate to high astigmatism. Methods Fifty adolescents myopia astigmatism (≥1.50 D) who underwent consecutive for least 1 year were included this study. The group comprised 25 subjects (25 eyes, 11 M, 14 F; age, 10.67 ± 1.46 years) fitted lenses. subjects, 11.45 1.63 traditional as a control. Corneal topography, visual acuity, axial length,...
To investigate the level of compliance with orthokeratology (ortho-k) guidelines and main behaviors poor to guide clinical care.A questionnaire was sent ortho-k patients in Eye Hospital Wenzhou Medical University (EHWMU) Mainland China who were prescribed lenses after January 2013 have worn for more than 1 year determine rate eight wear care behaviors. Follow-up visit then investigated among these using a retrospective survey.A total 1,500 questionnaires distributed, 405 responded. The mean...
To determine if the spatial distribution of relative corneal refractive power shift (RCRPS) explains retardation axial length (AL) elongation after treatment by either orthokeratology (OK) or multifocal soft contact lenses (MFCLs).Children (8-14 years) were enrolled in OK (n = 35) MFCL 36) groups. RCRPS maps derived computing difference between baseline and 12-month topography then subtracting apex values. Values at same radius averaged to obtain profile, from which four parameters...
Seaweeds are considered to be third-generation renewable biomasses, the comprehensive utilization of which has drawn increasing attention in recent years. A novel cold-active alginate lyase (VfAly7) was identified from Vibrio fortis and biochemically characterized for brown seaweed utilization. The gene high-level expressed Pichia pastoris, with an enzyme yield 560 U/mL a protein content 9.8 mg/mL by high-cell density fermentation. recombinant most active at 30 °C pH 7.5, respectively....