A5069955865- Intracranial Aneurysms: Treatment and Complications
- Polyamine Metabolism and Applications
- Vascular Malformations Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Amino Acid Enzymes and Metabolism
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Hematological disorders and diagnostics
- Acute Lymphoblastic Leukemia research
- Neurosurgical Procedures and Complications
- Hemoglobinopathies and Related Disorders
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Hemophilia Treatment and Research
- Platelet Disorders and Treatments
- Cannabis and Cannabinoid Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Aldose Reductase and Taurine
- Erythrocyte Function and Pathophysiology
- Retinoids in leukemia and cellular processes
- Blood Coagulation and Thrombosis Mechanisms
- Antifungal resistance and susceptibility
- T-cell and Retrovirus Studies
Japanese Red Cross Nagoya Daini Hospital
2022-2025
Udayana University
2024
Nagoya University Hospital
2024
Nagoya University
2017-2023
Noguchi Hospital
2004-2023
Tokyo National Hospital
2019
Tokyo University of Agriculture
2008
Nihon University
2004
Kagoshima University Hospital
1997
Mie University
1986-1994
Abstract Objective: Invasive Trichosporon infection has been increasingly recognized in patients with hematologic malignancies. Our study aims to clarify the clinical characteristics of this disease and factors influencing patient prognosis. Patients methods: We retrospectively analyzed 33 cases fungemia (TF) malignancies treated at our collaborating five hospitals Japan between 1992 2007. Results: The majority these had acute leukemia (82%), neutropenia (85%), a history intensive...
Background. It was assessed whether addition of vincristine (VCR) to remission induction therapy would increase the complete (CR) rate, and, secondarily, 12 courses maintenance—intensification produce longer survival than 4 in adult acute myeloid leukemia (AML). Methods. A randomized comparison individualized conducted between daunorubicin, behenoyl cytarabine, 6-mercaptopurine, and prednisolone with or without VCR. After 3 intensive consolidation therapy, given every 6 weeks. Results. Of...
Abstract Objective To evaluate the midterm surgical outcomes and factors associated with extent of resection (EOR), postoperative visual improvement, risk for cerebrospinal fluid (CSF) leaks in cases endoscopic endonasal approach (EEA) tuberculum sellae meningiomas (TSMs), including utilizing malleable forceps. Design Retrospective clinical study. Setting Single-center tertiary referral hospital. Participants Twenty-two patients who underwent EEA TSMs between November 2013 April 2024. Main...
Delayed cerebral ischemia (DCI) is a crucial determinant of the prognosis patients with aneurysmal subarachnoid hemorrhage (aSAH). In Japan, fasudil has traditionally been used to prevent vasospasm after aSAH. The effectiveness clazosentan, selective endothelin receptor A antagonist, in preventing vasospasm, significant contributor DCI, was recently demonstrated. This study aimed compare efficacy and safety perioperative management using clazosentan- fasudil-based therapies. multicenter,...
The surgical techniques for treatment of chronic subdural hematoma (CSDH), a common neurosurgical condition, have been discussed in lot clinical literature. However, the recurrence proportion after CSDH surgery remains high, ranging from 10 to 20%. standard procedure involves craniostomy evacuate hematoma, but irrigating cavity during is debatable. authors hypothesized that choice irrigation fluid might be key factor affecting outcomes surgery. This multicenter randomized controlled trial...
For food industry production processes and other uses, a mold that produces high levels of feruloyl esterase was obtained from laboratory collections sources. It Aspergillus awanmori G-2 esterase. The purified using ion-exchange chromatography, size-exclusion HPLC chromatography. enzyme identified as monomer protein Its optimum temperature pH were, respectively, 40 degrees C 5. activity stable at 3 to combined with xylan starch, but it absorbed by cellulose. km the 0.0019% (0.01 mM). showed...
A 70-year-old man was admitted to our hospital because of paraplegia. spinal epidural tumor (Th VII-XI) diagnosed by magnetic resonance imaging and resected. Histological examination the showed non-Hodgkin's lymphoma diffuse large cell type (Lymphoma Study Group classification), with a B phenotype. The clinical stage IEA Ann Arbor classification. Radiation therapy involved field performed (total dose: 40 Gy), followed six courses modified cyclophosphamide, adriamycine, vincristine,...
We report a 31-year-old female who had repeated thrombosis and was diagnosed as having congenital homozygous protein C deficiency based on decreased antigen activity, the findings of family history. This patient shown no symptom until age 27 years, when she cerebral infarction first symptom. Low molecular weight heparin useful for disseminated intravascular coagulation (DIC) that complicated in this patient.(Internal Medicine 31 : 922-925, 1992)
De novo aneurysms generally develop in healthy vessels after parent artery occlusion for large internal carotid (ICA) aneurysm, possibly owing to increased hemodynamic stress the remaining vessels. In recent years, there has been a shift toward flow diverter stent treatment. However, is lack of direct evidence and data that prove this change The authors compared healthy-side before treatments.The included patients who underwent 3D cine phase-contrast MRI ICA aneurysm Spatially temporally...
Serum levels of lipids and lipoproteins were examined in individuals with hyperlipidemia treated atorvastatin or colestimide healthy volunteers. Modified low-density lipoprotein (LDL) was measured by its faster electrophoretic mobility expressed as charge modification frequency (CMF). total cholesterol (t-chol), triglyceride (TG), very (VLDL)-chol, (LDL)-chol, CMF significantly higher hyperlipidemia, but there no significant difference serum high-density (HDL)-chol between hyperlipidemic...
Effects of methylglyoxal bis(butylamidinohydrazone) (MGBB), a reversible inhibitor ornithine decarboxylase (ODC) and S-adenosylmethionine (AdoMetDC), on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced increases ODC AdoMetDC activities, mRNA level polyamine contents in mouse skin were investigated connection with tumor formation. Formation papillomas by applications TPA to 7,12-dimethylbenz[a]anthracene (DMBA)-initiated was effectively inhibited simultaneous topical MGBB, MGBB also...
Cone beam computed tomography (CBCT) images are degraded by artifacts due to endovascular implants. We evaluated the use of streak metal artifact reduction technique (SMART) in non-contrast CBCT after neurosurgery obtained from 148 patients (125 with aneurysm and 23 dural arteriovenous fistula [dAVF]). Three neurosurgeons cistern brain surface visibility without SMART correction based on a 4-point scale (1, excellent; 2, good; 3, limited; 4, insufficient). Significant improvement was...
Octreotide acetate, a long-acting somatostatin analogue, is effective in controlling and markedly reducing the symptoms of carcinoid crisis. We report patient with syndrome prolonged survival for 4.5 years high dose octreotide therapy survived 7.5 after first flushing, spite episodes severe Dose escalation was required order to control symptoms, final dosage 5, 950 μg/day. Although administration such has never been reported before, we found that could be used at this safely without inducing...