- Obesity, Physical Activity, Diet
- Metabolomics and Mass Spectrometry Studies
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Advanced MRI Techniques and Applications
- Children's Physical and Motor Development
- Neonatal Health and Biochemistry
- Infant Development and Preterm Care
- Nerve injury and regeneration
- Heme Oxygenase-1 and Carbon Monoxide
- Facial Nerve Paralysis Treatment and Research
- Child Development and Digital Technology
- Sleep and related disorders
- Inflammasome and immune disorders
- COVID-19 and Mental Health
- Neuroscience and Neuropharmacology Research
- Physical Activity and Health
- Neurological Disease Mechanisms and Treatments
- Ear and Head Tumors
- Migraine and Headache Studies
- Mesenchymal stem cell research
- Motor Control and Adaptation
- Mitochondrial Function and Pathology
- Traditional Chinese Medicine Analysis
- Antibiotics Pharmacokinetics and Efficacy
Peking Union Medical College Hospital
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
People's Hospital of Xinjiang Uygur Autonomous Region
2021-2024
Chinese University of Hong Kong
2021-2024
Hong Kong Baptist University
2019-2024
Chengdu University of Traditional Chinese Medicine
2022-2023
Southern Medical University
2014-2023
Zhujiang Hospital
2023
Zhejiang University
2022
Southwest University
2022
Multipotent mesenchymal stromal cell (MSC) therapy has been widely recognized as a feasible strategy for regenerating injured myocardial tissue. However, little is known about the efficacy of intravenous injection allogeneic umbilical cord (UC) MSCs in preclinical models porcine infarction.Different dosages UC-MSCs or vehicle [phosphate-buffered saline (PBS)] were delivered intravenously into an acute infarction (AMI) model twice after coronary ligation. Echocardiography was performed to...
Critical tissues that undergo regeneration in periodontal tissue are of mesenchymal origin; thus, investigating the regulatory mechanisms underlying fate ligament stem cells could be beneficial for application regeneration. Nitric oxide (NO) regulates many biological processes developing embryos and adult cells. The present study was designed to investigate effects NO on function human (PDLSCs) as well elucidate molecular mechanisms. Immunofluorescent staining flow cytometry were used cell...
Bilirubin-induced neurological dysfunction (BIND), a severe complication of extreme neonatal hyperbilirubinemia, could develop into permanent neurodevelopmental impairments. Several studies have demonstrated that inflammation and nerve cell death play important roles in bilirubin-induced neurotoxicity; however, the underlying mechanism remains unidentified.The present study was intended to investigate whether pyroptosis, highly inflammatory form programmed death, participated...
This study aimed to investigate the extent which preschool children in Hong Kong meet World Health Organization's (WHO) 24-h movement guidelines and examine associations between meeting body weight status. Data from 251 preschoolers (141 boys) aged 3 6 years were analysed. The wore an activPAL for 7 consecutive days measure physical activity sleep. Their screen time was reported by their parents using validated questions. status classified as underweight, normal or overweight/obese. A total...
Maffucci syndrome is a rare disease characterized by multiple enchondromas and soft-tissue hemangiomas. Additionally, neuroendocrine tumors including pituitary adenomas have been described in these patients. The underlying genetic etiology lies somatic mosaicism of mutations isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2). This report describes patient with who presented intracranial the skull base suprasellar region. underwent resection both tumors, revealing histopathological diagnoses...
Kernicterus is a severe complication of extreme neonatal hyperbilirubinemia. Prolonged exposure to high-level unconjugated bilirubin (UCB) directly damages brain tissue. Neuroinflammation believed contribute UCB-induced neurotoxicity. Pyroptosis has been as highly inflammatory form programmed cell death. Therefore, this study aimed explore whether pyroptosis was involved in the pathogenesis UCB neurotoxicity kernicterus model rats. VX-765, specific inhibitor caspase-1, intraperitoneally...
Object Hypoglossal-facial nerve neurorrhaphy is a widely used method for treating complete facial palsy. However, the classic surgical procedure using “side”-to-end not suitable incomplete palsy (IFP), because sectioning of compromises remnant axons and potential spontaneous reinnervation. For treatment persistent IFP, authors investigated in rats modified hypoglossal-facial “side”-to-side neurorrhaphy. Methods An IFP model was created by crushing then ligating injury site to limit axonal...
This study aimed to examine the associations between physical activity (PA), sedentary behavior, sleep and posttraumatic stress disorder (PTSD) among undergraduate students during coronavirus disease 2019 (COVID-19) pandemic in China.A total of 3178 university responded an online questionnaire December 2020 January 2021. Participants self-reported time they spent on PA, screen after (over past seven days) outbreak peak (from March 2020). Their quality was measured using Chinese version...