Hiroki Mieno

ORCID: 0000-0002-0432-0832
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About
Contact & Profiles
Research Areas
  • Drug-Induced Adverse Reactions
  • Urticaria and Related Conditions
  • Glaucoma and retinal disorders
  • Corneal surgery and disorders
  • Retinal Imaging and Analysis
  • Retinal and Macular Surgery
  • Intraocular Surgery and Lenses
  • Retinal Diseases and Treatments
  • Autoimmune Bullous Skin Diseases
  • Contact Dermatitis and Allergies
  • Metastasis and carcinoma case studies
  • Ophthalmology and Visual Impairment Studies
  • Genetic factors in colorectal cancer
  • Gastroesophageal reflux and treatments
  • Vascular Malformations Diagnosis and Treatment
  • Ocular Surface and Contact Lens
  • Mast cells and histamine
  • Cutaneous lymphoproliferative disorders research
  • Ocular Infections and Treatments
  • Galectins and Cancer Biology
  • Cardiovascular Function and Risk Factors
  • Ocular and Laser Science Research
  • Tissue Engineering and Regenerative Medicine
  • Acne and Rosacea Treatments and Effects
  • Cellular Mechanics and Interactions

Kyoto Prefectural University of Medicine
2016-2025

The University of Tokyo
2024

Kyushu University
2024

Oida Hospital
2021-2022

National Defense Medical College
2012

Red Cross Hospital
1999

Kitasato University Hospital
1993-1994

Kitasato University East Hospital
1993-1994

To clarify the importance of administering topical steroids for treatment Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) with ocular involvement in acute phase.Retrospective case series.Using medical records SJS/TEN patients treated at Kyoto Prefectural University Medicine Hospital, Kyoto, Japan, between July 2006 and 2017, findings, steroid dosage, systemic sequelae were retrospectively examined. The level cytokines tear fluid serum samples was also analyzed.This study...

10.1016/j.ajo.2023.05.010 article EN cc-by-nc-nd American Journal of Ophthalmology 2023-05-13

The PreserFlo MicroShunt (PMS) is a minimally invasive surgical device for glaucoma management. However, postoperative hypotony remains significant complication. This retrospective cohort study analyzed 471 eyes to evaluate the efficacy of PMS implantation in reducing intraocular pressure (IOP) and medication dependency, as well identify risk factors associated with hypotony. median IOP decreased significantly from 19 mmHg preoperatively 10 three months postoperatively, medications score...

10.1038/s41598-025-92879-9 article EN cc-by-nc-nd Scientific Reports 2025-03-11

To investigate the change of chronic diabetic macular oedema (DMO) in vitrectomised eyes when administration sodium-glucose cotransporter 2 (SGLT2) inhibitors is initiated as a systemic medical treatment.This study involved 10 five patients with DMO lasting more than 6 months who had previously undergone vitrectomy and whose treatments were newly changed to SGLT2 inhibitors. In this study, was defined persistent diffuse despite ophthalmic treatment diabetes. Patients received antivascular...

10.1136/bmjophth-2017-000130 article EN cc-by-nc BMJ Open Ophthalmology 2018-07-01

Abstract Background This study aimed to investigate the pre- and post-surgery reading ability in patients with idiopathic epiretinal membrane (ERM) evaluate whether measurement of performance is a helpful test addition visual acuity (VA) as an assessment measure. Methods prospective observational involved 42 eyes 40 ERM. Best-corrected (BCVA), ability, metamorphopsia score were evaluated at baseline 3, 6, 12 months post-surgery. As outcome measure, each patient (i.e., overall performance)...

10.1186/s12886-020-01364-6 article EN cc-by BMC Ophthalmology 2020-03-10

To compare the commonly used formulas for intraocular lens (IOL) selection using IOLMaster®700 (Carl Zeiss Meditec) and to evaluate Barrett Universal II (BU-II) formula accuracy when Vivinex™ iSert® XY1 IOL (Hoya Corporation Medical Division).A retrospective chart review was performed that included patients who underwent uneventful cataract surgery with in-the-bag insertion of IOL. Prediction errors at 3 months postoperative IOLMaster® 700 Haigis, Holladay 1, SRK/T, BU-II were compared. As a...

10.4103/ijo.ijo_3455_20 article EN cc-by-nc-sa Indian Journal of Ophthalmology 2021-08-25

This study aimed to clarify the etiologic factors predicting acute ocular progression in SJS/TEN, and identify patients who require immediate intensive ophthalmological treatment. We previously conducted two Japanese Surveys of SJS/TEN (i.e., cases arising between 2005–2007 2008–2010), obtained medical records, including detailed dermatological findings, 230 patients. Acute severity was evaluated as none, mild, severe, very severe. A multi-state model assuming Markov process based on Cox...

10.1371/journal.pone.0260730 article EN cc-by PLoS ONE 2021-12-23

Background/aims In a previous genome-wide association study of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) patients we reported the between SJS/TEN and prostaglandin E receptor 3 (PTGER3) gene, that its protein PGE 2 (EP3) was markedly downregulated in conjunctival epithelium patients. Here examined EP3 expression eyelid epidermis with severe ocular complications investigated function EP3. Methods For immunohistochemical study, obtained samples from five without (control...

10.1136/bjophthalmol-2018-313587 article EN British Journal of Ophthalmology 2019-04-18

Purpose To investigate the efficacy of aflibercept for treatment diabetic macular edema via a treat-and-extend regimen. Methods This prospective, single-center, open-label, interventional study involved 30 patients with best-corrected visual acuity (BCVA) ≤0.6 and central retinal thickness (CRT) ≥300 µm. The enrolled eyes each received monthly intravitreal injection until CRT decreased below 300 µm, upon which administration interval was extended 1 month once again increased to Main...

10.3341/kjo.2020.0003 article EN cc-by-nc Korean Journal of Ophthalmology 2020-01-01

Abstract Background/Objectives: Little is known about effects of climatic factors on intraocular pressure (IOP) in normal eyes. The purpose this study to investigate correlation between and Goldmann applanation tonometer-measured IOP (GAT-IOP) eyes under everyday conditions. Subjects/Methods: Data from 2,341 subjects; mean age, 56.9 years) who participated a population-based glaucoma survey Japan were analyzed using the multivariable regression analysis, which GAT-IOP was response variable;...

10.21203/rs.3.rs-3709280/v1 preprint EN cc-by Research Square (Research Square) 2024-01-23

We describe a rare case of carotid-cavernous sinus fistula (CCF) in 91-year-old woman's right eye with functional filtering bleb. Upon examination, best-corrected visual acuity was light perception and intraocular pressure (IOP) 14 mmHg, shallow anterior chamber, swollen bleb, dilated episcleral veins, choroidal detachment, ocular manifestations accompanied CCF were observed. During the healing process post transcatheter arterial embolization (TAE), significant hypotony prolonged detachment...

10.4103/ijo.ijo_585_24 article EN Indian Journal of Ophthalmology - Case Reports 2024-10-01

Post-gasterectomy obstraction of the afferent loop is a serious disease where sudden abdominal pain occurs once complete occlusion develops, and unless appropriate surgical measures are taken early, condition leads to dilatation, perforation, necrosis loop, with fatal outcome. In this paper we investigated pathology clinical features discuss its problems in 13 cases experienced at hospital 72 domestic which could be seen literature. resconstructive procedures for initial operations....

10.3919/ringe1963.55.2491 article EN The journal of the Japanese Practical Surgeon Society 1994-01-01
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