A5027372364- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Synthesis and Biological Activity
- Cancer therapeutics and mechanisms
- Berberine and alkaloids research
- Food Quality and Safety Studies
- Phytochemistry and Biological Activities
- Biofuel production and bioconversion
- Synthesis and biological activity
- Tannin, Tannase and Anticancer Activities
- Neuroinflammation and Neurodegeneration Mechanisms
- Botanical Research and Applications
- Eicosanoids and Hypertension Pharmacology
- Polysaccharides and Plant Cell Walls
- Quinazolinone synthesis and applications
- Biocrusts and Microbial Ecology
- Bioactive natural compounds
- Diet, Metabolism, and Disease
- Sulfur Compounds in Biology
- Sesquiterpenes and Asteraceae Studies
- Ziziphus Jujuba Studies and Applications
- Phytoestrogen effects and research
- Heme Oxygenase-1 and Carbon Monoxide
- Natural Antidiabetic Agents Studies
- Biochemical and Molecular Research
Chinese Academy of Sciences
2015-2022
Northwest Institute of Plateau Biology
2016-2022
Qinghai Tibetan Hospital
2017-2022
Xinjiang Institute of Ecology and Geography
2017-2021
Institute of Tibetan Plateau Research
2015-2021
Research Institute of Forestry
2018
Shaanxi University of Technology
2018
Qinghai University
2018
University of Chinese Academy of Sciences
2015-2016
Diabetes mellitus (DM) is a serious metabolic disorder, where impaired postprandial blood glucose regulation often leads to severe health complications. The natural chemical erythritol C4 polyol approved by the U.S. Food and Drug Administration for use as sweetener. Here, we examined potential role in control of levels DM. An anti-postprandial hyperglycemia effect upon administration (500 mg kg-1) was demonstrated alloxan-induced DM model mice monitoring changes after intragastric drugs...
Efficient access to evodiamine and its analogues is presented <italic>via</italic> Lewis acid catalysis. In this reaction, three chemical bonds two heterocyclic-fused rings are constructed in one step.
Dracocephalum heterophyllum was a traditional Tibetan medicine possesses various pharmacological effects involved in anti-inflammatory, antibacterial activities. However, its anti-hepatitis, antioxidant activity and bioactive compounds have not been reported, the objective of this research work to investigate D. extracts.
A phytochemical investigation on Lagotis brevituba led to the isolation and characterisation of 11 phenolic compounds: p-hydroxy-benzoic acid 1, methyl 3,4-dihydroxybenzoate 2, vanillic 3, protocatechuic 4, caffeic 5, glucose ester (E)-ferulic 6, p-coumaric 7, vanillin 8, diosmetin-7-O-β-d-glucoside 9, chrysoeriol 10 luteolin 11. Their structures were elucidated using spectroscopic methods by comparison with data in literature. Compounds 1–6 first obtained from genus Lagotis, compounds 1–9...
Two new isoquinoline alkaloids, hypecocarpinine (1) and leptocaramine (2) along with five known ones including leptopidine (3), corydamine (4), protopine (5), dihydroprotopine (6) oxohydrastinine (7), were isolated from Hypecoum leptocarpum Hook. f. et Thoms. Structures of the compounds elucidated using spectroscopic methods, UV, IR, HR-ESI-MS, 1 D 2 NMR. The cytotoxic activities these evaluated MTT assay. results showed that 2, 4, 7 have moderate cytotoxicity against human lung cancer...
Pharmacognosy Magazine,2018,14,56,418-424.DOI:10.4103/pm.pm_139_17Published:August 2018Type:Original ArticleAuthors:Haiyan Duan, Ming'en Cheng, Jian Yang, Changjiangsheng Lai, Liangping Zha, Yu Hu, Huasheng Peng, and Luqi Huang Author(s) affiliations:Haiyan Duan1, Cheng2, Yang3, Lai3, Zha2, Hu2, Peng1, Huang3 1 School of Pharmacy, Anhui University Chinese Medicine, Hefei; State Key Laboratory Breeding Base Dao-di Herbs, National Resource Center for Materia Medica, China Academy Medical...
Traditional Tibetan medicine provides an abundant source of knowledge on human ailments and their treatment. As such, it is necessary to explore active single compounds used treat these discover lead with good pharmacologic properties. In this present work, animal medicine, Osteon Myospalacem Baileyi extracts have been separated using a two‐dimensional preparative chromatographic method obtain high purity as part the following pharmacological research. Five high‐purity cyclic dipeptides from...
Pterocephalus hookeri, as a kind of popular traditional Tibetan medicine, is reputed to treat inflammatory related diseases. In the present work, cyclooxygenase-2 functionalized affinity solid-phase extraction HPLC system was developed and combined with preparative-HPLC for rapidly screening separating ligand from P. hookeri extracts. Firstly, ligands were screened extracts by system. Then directed results, recognized potential active compounds targeted separated. As result, major inhibitor...
To establish a quantitative method for determination of gallic acid, original catechins, chlorogenic caffeic syringic acid in Lycium ruthenicum.The sample was separated on an ODS column (4. 6 mm x 250 mm, 5 pnm), eluted with methanol and water containing 0. 1% detected wavelength at 280 nm, flow rate 1. 0 mL min(-1).The linearity six components were good (r = 0.9999). The average recoveries (n=5) the constituents 97. 70% (RSD 2.3%), 99.64% 1.8%), 100.7% 2.1%), 99.98% 2.6%), 99.60% 2.2%),...