A5087862370- Veterinary Equine Medical Research
- Tendon Structure and Treatment
- Veterinary Orthopedics and Neurology
- Shoulder Injury and Treatment
- Osteoarthritis Treatment and Mechanisms
- Gastrointestinal motility and disorders
- Sports injuries and prevention
- Wound Healing and Treatments
- Musculoskeletal synovial abnormalities and treatments
- Exercise and Physiological Responses
- Diverticular Disease and Complications
- Infectious Diseases and Mycology
- Periodontal Regeneration and Treatments
- Veterinary Practice and Education Studies
- Nail Diseases and Treatments
- Animal Behavior and Welfare Studies
- Winter Sports Injuries and Performance
- Animal health and immunology
- Effects of Environmental Stressors on Livestock
- Orthopedic Surgery and Rehabilitation
- Cutaneous Melanoma Detection and Management
- Reproductive Physiology in Livestock
- Entomological Studies and Ecology
- Musculoskeletal pain and rehabilitation
- Acupuncture Treatment Research Studies
Charles Sturt University
2017-2025
Kerala Veterinary and Animal Sciences University
2010-2018
Roslin Institute
2016
University of Edinburgh
2015
North Carolina State University
2010-2013
Center for Translational Molecular Medicine
2013
Leverhulme Trust
2013
Cornell University
2013
University of California, Davis
2013
University of Glasgow
2007-2010
Sonography is commonly used for diagnosis of desmopathy the proximal part suspensory ligament in horses. However, magnetic resonance (MR) imaging has been stated to be superior detecting disease and localizing lesions. In this retrospective study 39 horses or 46 hind limbs with lameness due plantar metatarsal pain, clinical diagnostic findings are discussed sonography MR compared examination ligament. With interpreted as gold standard, was diagnosed 21 limbs, pain unknown cause 12, an...
Gold nanoparticles (AuNPs) have great potential as carriers for local drug delivery and a primary therapeutic treatment of inflammation. Here we report on the AuNP-synovium interaction in an ex vivo model intra-articular application joint Sheets porcine femoropatellar synovium were obtained post mortem each side tissue samples was maintained separate fluid environment. Permeability to AuNPs different sizes (5-52 nm) biomarker levels inflammation determined characterize particle with...
Osteoarthritis of the distal tarsal joints, affecting centrodistal and tarsometatarsal is a common cause hindlimb lameness in horses. This paper describes outcome intra-articular treatment 51 horses with condition either methylprednisolone acetate (mpa) or triamcinolone acetonide (tr), without hyaluronic acid (ha). The was assessed terms changes horses' grade lameness. Follow-up information obtained from owners by means telephone questionnaire. Horses treated once mpa tr, ha, improved after...
Summary Permanent tracheostomy is sometimes required in horses with severe and irreversible obstructive upper airway conditions. Abnormal respiratory noise altered vocalisation may be of concern to owners its influence on mare‐foal recognition bonding should considered. Reversal a permanent tracheostoma the horse has not been described. This case report presents 13‐year‐old Quarter Horse mare longstanding that underwent primary surgical closure stoma 6 years after resolution underlying...
Intralesional chemotherapeutic administration represents an important treatment option for equine cutaneous neoplasia. Tigilanol-tiglate (TT), a novel molecule extracted from Fontainea picrosperma, Australian rainforest plant, is registered intratumoural of canine MCT, leading to rapid oncosis and tumour slough. Evidence horses limited but suggests that efficacy may be similar. To evaluate the response TT in with sarcoids (fibroblastic/nodular) melanomas. Two noncontrolled prospective...
Tendon injuries are common in athletic humans and horses. Ultrasonography is the diagnostic method of choice horses with tendon but there increasing application magnetic resonance (MR) imaging to monitor follow-up healing. A core lesion was created superficial digital flexor (SDFT) each forelimb four One euthanized at 2, 4, 8, 12 weeks after creation lesion. MR examinations SDFT were performed immediately post mortem a 1.5 T Siemens Symphony magnet compared histologic findings. Measurements...
Tendon and ligament injuries are common causes of impaired performance in equine athletes. Gray‐scale ultrasonography is the current standard method for diagnosing monitoring these injuries, however this modality only provides morphologic information. Elastography an ultrasound technique that allows detection measurement tissue strain, may provide valuable mechanical information about tendon injuries. The purpose study was to determine feasibility, reproducibility, repeatability...
Compression elastography is an ultrasonographic technique that estimates tissue strain and may have utility in diagnosing monitoring soft injuries the equine athlete. Recently, has been proven to be a feasible repeatable imaging modality for evaluating normal tendons ligaments of distal forelimb. The purposes this prospective study were investigate ability detect spontaneously occurring lesions diagnosed with magnetic resonance (MRI) gray‐scale ultrasound (US) characterize differences...
Normal wound healing progresses through a series of interdependent physiological events: inflammation, angiogenesis, re-epithelialization, granulation tissue formation and extracellular matrix remodeling. Alterations in this process as well the bacterial type load on may alter rate. The purpose study was to evaluate effect topical Saccharomyces boulardii acute cutaneous wounds, using prospective, controlled, experimental study, with six bred landrace pigs. All wounds healed without apparent...
Early diagnosis of cartilage disease at a time when changes are limited to depletion extracellular matrix components represents an important diagnostic target reduce patient morbidity. This report is present proof concept for nanoparticle dependent barrier imaging in large animal model including the use clinical magnetic resonance (MRI). Conditioned (following depletion) and unconditioned porcine metacarpophalangeal was evaluated on basis fluorophore conjugated 30 nm 80 spherical gold...
High-field MRI of the proximal metacarpal/metatarsal region has been associated with great diagnostic potential and clinical reports standing low-field forelimb suggest same. To better understand outcomes suspensory region, a prospective survey study was conducted users widely available system questioned on their experience, operating procedures, interpretation findings. Response data included scores modified Likert scale from which weighted ratings were calculated for statistical analyses....
Various radiographic rating scales have been described for use in horses with distal tarsal osteoarthritis but little information is available on their reliability. The aim of this study was to develop a scale based the results an expert consultation process (the Delphi process), and test reliability scale. Seven features were identified as important indicators these then incorporated scale, which used 100‐mm‐long visual analog On two occasions nine equine veterinarians applied verbal...
Autologous conditioned serum (ACS) is a commonly administered intra-articular treatment for the management of osteoarthritis in athletic horses.To investigate influence exercise on concentration cytokines non-commercial method ACS production.Non-randomised cross over design.Whole blood was obtained from eight healthy Standardbred horses immediately prior to, 1 h and 24 following single bout exhaustive exercise. Blood processed using production. Fluorescent microsphere immunoassay (FMIA)...
Outcome measures are essential for monitoring treatment efficacy. The lack of quality movement in equine physiotherapy and rehabilitation impairs evidence-based practice. To develop a new field-based outcome measure, it is necessary to determine movements most frequently observed during assessment performance management cases. An online survey 81 sports medicine veterinarians allied-health clinicians was conducted. key identified included walk trot on both firm soft surfaces straight line...
Summary Desmitis of the origin suspensory ligament is a common injury sport horses; however, it remains diagnostic challenge. The anatomy region can lead to difficulties localising lameness. Diagnostic imaging may be complicated by overlying structures and limitations modalities readily available. A logical approach clinical examination, analgesia multimodal help overcome these difficulties.
Abstract Objective To assess fracture gap reduction and stability of linear vs triangular 4.5‐mm lag screw repair experimental, uniarticular, complete forelimb proximal phalanx (P1) fractures. Study design Experimental. Sample population Fourteen equine cadaver limbs/horses. Methods Simulated fractures were repaired with 2 screws under 4‐Nm insertion torque (linear repair). Computed tomography (CT) imaging was performed the leg unloaded loaded to forces generated while walking. The revised...
To determine the influence of screw configuration on reduction and stabilization simulated complete lateral condylar fracture.
Synovial infections (SI) are common in horses of all ages and can be associated with high rates morbidity mortality. Identifying factors influencing survival return to function may useful for management affected individuals determination prognosis. The objectives this study were identify foals SI presented an equine hospital. This is a retrospective case series. Data collected from medical records that single hospital between April 1st, 2008 May 2017. Long-term follow up was obtained by...