A5009340831- Ophthalmology and Visual Impairment Studies
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Corneal Surgery and Treatments
- Smart Grid Energy Management
- Hybrid Renewable Energy Systems
- Microgrid Control and Optimization
- Cancer Mechanisms and Therapy
- Flood Risk Assessment and Management
- melanin and skin pigmentation
- FOXO transcription factor regulation
- Bee Products Chemical Analysis
- Genomics, phytochemicals, and oxidative stress
- Heat shock proteins research
- Hidradenitis Suppurativa and Treatments
- Robotic Mechanisms and Dynamics
- Safety and Risk Management
- Geographies of human-animal interactions
- Theoretical and Computational Physics
- Chromium effects and bioremediation
- Quantum chaos and dynamical systems
- Fiscal Policy and Economic Growth
- Nasolacrimal Duct Obstruction Treatments
PLA Army Engineering University
2025
Zhengzhou University
2021-2025
Henan University
2024-2025
Tianjin Medical University
2015-2024
Tianjin Medical University Eye Hospital
2015-2024
Chengdu University of Traditional Chinese Medicine
2023-2024
Fujian Agriculture and Forestry University
2024
Xihua University
2023-2024
Wuhan Polytechnic University
2023
Southwest Minzu University
2023
<h3>Importance</h3> Time spent in outdoor activities has decreased owing to home confinement for the coronavirus disease 2019 (COVID-19) pandemic. Concerns have been raised about whether may worsened burden of myopia substantially time outdoors and increased screen at home. <h3>Objective</h3> To investigate refractive changes prevalence school-aged children during COVID-19 confinement. <h3>Design, Setting, Participants</h3> A prospective cross-sectional study using school-based...
// Xiaoyu Zeng 1, * , Lin Liu Mengzhu Zheng 2, Huimin Sun 3 Juanjuan Xiao 1 Tao Lu Guangqian Huang Pianpian Chen 4 Jianmin Zhang Feng Zhu Hua Li 5 Qiuhong Duan Department of Biochemistry and Molecular Biology, School Basic Medicine, Huazhong University Science Technology, Wuhan, Hubei, 430030, PR China 2 Pharmacy, Tongji Medical College, Urology, Xijing Hospital, the Fourth Military University, Xi'an, Shaanxi, 710032, Neurobiology, Traditional Chinese Materia Medica, Shenyang Pharmaceutical...
Abstract Breast cancer is the most common and leading cause of cancer-related deaths in women. Increasing molecular targets have been discovered for breast prognosis therapy. However, there still an urgent need to identify new biomarkers. Therefore, we evaluated biomarkers that may aid diagnosis treatment cancer. We searched three mRNA microarray datasets (GSE134359, GSE31448 GSE42568) identified differentially expressed genes (DEGs) by comparing tumor non-tumor tissues using GEO2R....
Abstract Purpose To study the epidemiology of myopia in school-aged children Tianjin and relationship between visual acuity-based screening refraction-based screening. Method This school-based prospective cohort was performed on from 42 elementary schools 17 middle Tianjin, China. Totally 14,551 children, ages ranging 5 to 16 years, were included this study. Uncorrected acuity (UCVA) determined by logarithmic tumbling E chart. Non-cycloplegic photorefraction examined Spot (v2.1.4)...
Progression of myopia in a school-aged population due to home confinement (January May 2021) during the COVID-19 pandemic has been previously reported. A key remaining question was whether spike children aged 6 8 years persisted.To investigate changes refractive status and prevalence 1 year after ended China.This cross-sectional study with cohort substudy prospectively evaluated data from school-based photoscreening Feicheng, China. Children 13 participated screenings 2015...
ABSTRACT Digestive system tumor, including esophageal gastric intestinal liver pancreatic and cholangiocarcinoma, are the most common tumors worldwide serve as a major cause of tumor‐related death. Cancer stem cells (CSCs) small group in that harbor self‐renewal, differentiation abilities, playing crucial role tumor initiation, progression, metastasis, supposed to be fundamental recurrence after conventional treatment. A comprehensive understanding targeting CSCs is key overcoming tumors. In...
T-LAK cell-originated protein kinase (TOPK), a serine/threonine kinase, is highly expressed in variety of tumors and associated with poor prognosis human malignancies. However, the activation mechanism TOPK still unrevealed. Herein, first we found that Src directly bound phosphorylated at Y74 Y272 vitro. Anti-phospho-TOPK was prepared, endogenous phosphorylation detected colon cancer cells, inhibited cells expressing low levels Src. Subsequently, stably transfected double mutated (TOPK-FF)...
Sichuan hilly area is located in southwest China, which have many area, a densely populated, economically active, frequent geological disasters area. In this paper, Neijiang City the region taken as test sample. This article, analyzes Land-Use and Land-Cover Changes (LUCC), meteorological hydrological data from 2015 to 2020, takes research object. We explored relationship between such collapse landslides that often occur natural ecological environment with LUCC factors, using GIS spatial...
Purpose . To observe ocular surface changes in Type II diabetic patients with different disease durations and to understand the correlations between clinical parameters durations. Methods In this cross-sectional, prospective study, 51 healthy controls 91 diabetes were enrolled. The diabetics divided into 3 subgroups according duration, including duration <10 y group, 10 20 ≥21 group. All subjects underwent examinations, lipid layer thickness (LLT), blinking rate, tear meniscus height...
Mesenchymal stem cells (MSCs) have been reported to promote long-term cellular and organ transplant acceptance due their immunotherapeutic characteristics. Previous work from our lab using a rat allograft model has shown that systemic infusion of MSCs inhibited corneal rejection prolonged graft survival. Here, we further investigated the effects local administration in same animal model. Donor-derived were isolated cultured while grafts obtained Wistar rats transplanted into Lewis hosts....
Growing evidences indicate that RNA-binding proteins (RBPs) play critical roles in regulating the RNA splicing, polyadenylation, stability, localization, translation, and turnover. Abnormal expression of RBPs can promote tumorigenesis. Here, we performed a CRISPR screen using an RBP pooled knockout library identified 27 potential with role supporting colorectal cancer (CRC) survival. We found deletion/depletion INTS3 triggered apoptosis CRC. The
Purpose This study aims to elucidate the longitudinal refractive and ocular biometric alterations in preschool children with high hyperopia who underwent early interventions.
// Xiaoming Fan 1, * , Qiuhong Duan Changshu Ke 2 Guiping Zhang 3 Juanjuan Xiao 1 Dan Wu Xiaoyu Zeng Jingwen Chen 4 Jinguang Guo Jie Zhou Fei Shi Feng Zhu Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University Science Technology, Wuhan, 430030, PR China Pathology, hospital, Shanghai Biyi Chemical Technology Co., Shanghai, 201203, Dermatology the General Hospital Air Force, Beijing, 100142, These authors have contributed equally to this work...