Nicholas P. Ryan

ORCID: 0000-0002-0878-8889
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About
Contact & Profiles
Research Areas
  • Traumatic Brain Injury Research
  • Cardiac Arrest and Resuscitation
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neonatal and fetal brain pathology
  • Infant Development and Preterm Care
  • Energy, Environment, and Transportation Policies
  • Advanced Neuroimaging Techniques and Applications
  • Functional Brain Connectivity Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Indian Economic and Social Development
  • Childhood Cancer Survivors' Quality of Life
  • Family and Disability Support Research
  • Energy, Environment, Economic Growth
  • Climate Change Policy and Economics
  • Resilience and Mental Health
  • Suicide and Self-Harm Studies
  • Injury Epidemiology and Prevention
  • Energy and Environment Impacts
  • Neuroscience of respiration and sleep
  • Adolescent and Pediatric Healthcare
  • Trauma and Emergency Care Studies
  • Psychological Well-being and Life Satisfaction
  • Corporate Finance and Governance
  • Topic Modeling
  • Environmental Sustainability in Business

Deakin University
2018-2025

Murdoch Children's Research Institute
2016-2025

The University of Melbourne
2016-2025

Royal Children's Hospital
2016-2025

Yale University
2018-2023

National Bureau of Economic Research
2023

Universidad de Murcia
2023

Eastern Health
2022

University of Utah
2021

Nationwide Children's Hospital
2021

This longitudinal study was designed to investigate whether or not social connectedness predicts psychological well‐being over time. Structural equation modeling used examine the temporal relations between these constructs assessed yearly for 3 years a sample of 1,774 10‐ 15‐year‐olds (at Time 1). Results indicated that global (i.e., combined across domains family, school, peers, and neighborhood) predicted well‐being, but no reciprocal relation found. However, were revealed by analyses...

10.1111/j.1532-7795.2012.00783.x article EN Journal of Research on Adolescence 2012-02-27

Abstract Pediatric traumatic brain injury (TBI) can result in a range of social impairments, however longitudinal recovery is not well characterized, and clinicians are poorly equipped to identify children at risk for persisting difficulties. Using prospective design, this study aimed evaluate the contribution non‐injury related resilience factors outcome problems from 12‐ 24‐months post‐TBI. 78 with TBI (injury age: 5.0–15.0 years) 40 age gender‐matched typically developing (TD) underwent...

10.1016/j.ijdevneu.2015.12.004 article EN International Journal of Developmental Neuroscience 2015-12-29

Emotion perception (EP) forms an integral part of social communication and is critical to attain developmentally appropriate goals. This skill, which emerges relatively early in development, driven by increasing connectivity among regions a distributed sociocognitive neural network may be vulnerable disruption from early-childhood traumatic brain injury (TBI). The present study aimed evaluate the very-long-term effect childhood TBI on EP, as well examine contribution injury-...

10.1089/neu.2013.3153 article EN Journal of Neurotrauma 2013-10-22

Children with traumatic brain injury (TBI) are at risk for social impairment, but research has yet to document the trajectory of these skills post-injury and factors that may predict problems. This study addressed gaps in knowledge, reporting on findings from a prospective, longitudinal follow-up investigated outcomes explored contributing two years post-injury. The sample included 113 children, 74 TBI 39 typically developing (TD) controls. participants were recruited presentation hospital....

10.1089/neu.2016.4692 article EN Journal of Neurotrauma 2017-02-08

Abstract Childhood and adolescence are critical periods for maturation of neurobiological processes that underlie complex social emotional behavior including Theory Mind (ToM). While structural correlates ToM well described in adults, less is known about the anatomical regions subsuming these skills developing brain or impact cerebral insult on acquisition establishment high‐level cognitive skills. This study aimed to examine differential influence age‐at‐insult pathology a sample children...

10.1002/hbm.22729 article EN Human Brain Mapping 2014-12-23

Traumatic brain injury (TBI) is a common cause of childhood disability, and associated with elevated risk for long-term social impairment. Though (pragmatic) communication deficits may be among the most debilitating consequences TBI, few studies have examined very outcomes as children TBI make transition to young adulthood. In addition, extent which reduced function contributes externalizing behaviors in survivors remains poorly understood. The present study aimed evaluate difficulty adult...

10.1016/j.ijdevneu.2013.10.002 article EN International Journal of Developmental Neuroscience 2013-10-15

Background Deficits in social cognition may be among the most profound and disabling sequelae of paediatric traumatic brain injury (TBI); however, neuroanatomical correlates longitudinal outcomes this domain remain unexplored. This study aimed to characterize cognitive longitudinally after TBI, evaluate use sub-acute diffusion tensor imaging (DTI) predict these outcomes. Methods The sample included 52 children with mild complex-severe TBI who were assessed on theory mind (ToM), pragmatic...

10.1017/s0033291717002057 article EN Psychological Medicine 2017-08-07

Deficits in theory of mind (ToM) are common after neurological insult acquired the first and second decade life, however contribution large-scale neural networks to ToM deficits children with brain injury is unclear. Using paediatric traumatic (TBI) as a model, this study investigated sub-acute effect on grey-matter volume three large-scale, domain-general (the Default Mode Network, DMN; Central Executive CEN; Salience SN), well two domain-specific implicated social-affective processes...

10.1093/scan/nsx066 article EN cc-by-nc Social Cognitive and Affective Neuroscience 2017-05-10

Previous studies in pediatric traumatic brain injury (TBI) have been variable describing the effects of severity on white-matter development. The present study used diffusion tensor imaging to investigate prospective sub-acute and longitudinal relationships between early clinical indicators severity, metrics, neuropsychological outcomes. Pediatric patients with TBI underwent magnetic resonance (MRI) (n = 78, mean [M] 10.56, standard deviation [SD] 2.21 years) at stage after (M 5.55, SD 3.05...

10.1089/neu.2016.4584 article EN Journal of Neurotrauma 2016-07-29

Objectives: To investigate rates of clinically significant externalizing behavior (EB) in young adult survivors pediatric traumatic brain injury (TBI) and evaluate the contribution pre- postinjury risk resilience factors to EB outcomes 16 years after injury. Setting: Melbourne, Australia. Participants: Fifty-five adults (mean age = 23.85 years; age: 1.0-12 years) admitted an emergency department following TBI between 1993 1997. Design: Longitudinal prospective study with data collected at...

10.1097/htr.0000000000000123 article EN Journal of Head Trauma Rehabilitation 2015-03-01

Childhood and adolescence coincide with rapid maturation synaptic reorganization of distributed neural networks that underlie complex cognitive-affective behaviors. These regions, referred to collectively as the 'social brain network' (SBN) are commonly vulnerable disruption from pediatric traumatic injury (TBI); however, mechanisms link morphological changes in SBN behavior problems this population remain unclear. In 98 children adolescents mild severe TBI, we acquired 3D T1-weighted MRIs...

10.1093/scan/nsw007 article EN cc-by-nc Social Cognitive and Affective Neuroscience 2016-01-21

Psychosocial deficits, such as emotional, behavioral and social problems, reflect the most common disabling consequences of pediatric traumatic brain injury (TBI). Their causes recovery likely differ from physical cognitive skills, due to disruption developing networks influence child's environment. Despite increasing recognition post-injury there exists a paucity research regarding incidence impairment, factors predicting risk resilience in domain over time since injury.

10.1017/s0033291722000186 article EN cc-by Psychological Medicine 2022-02-22

Abstract Objective To assess parent psychological distress in families of children with common chronic health conditions (CHC) and to explore relationships between distress, unmet supportive care needs children’s quality life (QoL). Method Cross-sectional study involving parents diagnosed a CHC 0 12 years age who had received treatment within the last 5 years. Eligible completed an online survey, that included Depression Anxiety Stress Scale (DASS-21) assessing 34-item assessment across 6...

10.1093/jpepsy/jsad074 article EN cc-by Journal of Pediatric Psychology 2023-10-14

Although childhood traumatic brain injury (TBI) has been linked to heightened risk of impaired social skills and behavior, current evidence is weakened by small studies variable methodological quality. To address these weaknesses, this international multi-cohort study involved synthesis data from two large observational cohort complicated mild-severe child TBI in Australia North America. Both adopted a unified approach collection coding procedures, providing the opportunity merge datasets...

10.1089/neu.2020.7057 article EN Journal of Neurotrauma 2020-09-04

Despite a well-documented association between childhood traumatic brain injury and elevated risk for internalizing externalizing behavior problems, the mechanisms through which family functioning contributes to individual variation in these behavioral outcomes remains poorly understood. This prospective cohort study aimed assess respective contribution of child emotion regulation (ER) post-injury problems at 1-year follow-up, with specific focus on evaluating role emotional dysregulation...

10.1016/j.jad.2025.01.023 article EN cc-by Journal of Affective Disorders 2025-01-01

An extensive library of symptom inventories has been developed over time to measure clinical symptoms traumatic brain injury (TBI), but this variety led several long-standing issues. Most notably, results drawn from different settings and studies are not comparable. This creates a fundamental problem in TBI diagnostics outcome prediction, namely that it is possible equate distinct tools inventories. Here, we present an approach using semantic textual similarity (STS) link scores across...

10.1089/neu.2024.0301 article EN Journal of Neurotrauma 2025-04-09
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