Emily L. Dennis
A5019628282- Traumatic Brain Injury Research
- Advanced Neuroimaging Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Cardiac Arrest and Resuscitation
- Neonatal and fetal brain pathology
- Posttraumatic Stress Disorder Research
- Anesthesia and Neurotoxicity Research
- Stress Responses and Cortisol
- Mental Health Research Topics
- Health, Environment, Cognitive Aging
- Gender Roles and Identity Studies
- Genetic Associations and Epidemiology
- Child Abuse and Trauma
- Homicide, Infanticide, and Child Abuse
- Neural dynamics and brain function
- Child and Adolescent Psychosocial and Emotional Development
- Resilience and Mental Health
- Adolescent Sexual and Reproductive Health
- Atomic and Subatomic Physics Research
- Bone and Joint Diseases
- Congenital heart defects research
- Cerebral Palsy and Movement Disorders
- Topic Modeling
University of Utah
2019-2025
George E. Wahlen Department of VA Medical Center
2020-2025
VA Salt Lake City Healthcare System
2021-2024
Icahn School of Medicine at Mount Sinai
2024
Anna Needs Neuroblastoma Answers
2024
Sunnybrook Health Science Centre
2023
Center for Clinical Research (United States)
2023
Madigan Army Medical Center
2023
McLean Hospital
2023
Uniformed Services University of the Health Sciences
2023
Structural and functional underconnectivity have been reported for multiple brain regions, systems, white matter tracts in individuals with autism spectrum disorders (ASD). Although recent developments complex network analysis established that the is a modular exhibiting small-world properties, level organization has not carefully examined ASD. Here we used resting-state MRI (n = 42 ASD, n 37 typically developing; TD) to show children adolescents ASD display reduced short long-range...
Abstract The ENIGMA‐DTI (diffusion tensor imaging) workgroup supports analyses that examine the effects of psychiatric, neurological, and developmental disorders on white matter pathways human brain, as well normal variation its genetic associations. seven ENIGMA disorder‐oriented working groups used workflow to derive patterns deficits using coherent coordinated model disease across cohorts worldwide. This yielded largest studies detailing in schizophrenia spectrum disorder (SSD), bipolar...
Pediatric concussion can disrupt functional brain network connectivity, but prospective longitudinal research is needed to clarify recovery and identify moderators of change. This study investigated connectivity (FC) up 6 months after pediatric concussion. concurrent cohort observational consecutively recruited children (aged 8 17 years) at 5 Canadian hospital emergency departments within 48 hours sustaining a or mild orthopaedic injury (OI). Children completed 3T MRI scanning postacutely (2...
Recently, carriers of a common variant in the autism risk gene, CNTNAP2, were found to have altered functional brain connectivity using MRI. Here, we scanned 328 young adults with high-field (4-Tesla) diffusion imaging, test hypothesis that this gene would structural connectivity. All participants (209 women, 119 men, age: 23.4±2.17 SD years) 105-gradient high-angular-resolution imaging (HARDI) at 4 Tesla. After performing whole-brain fiber tractography full angular resolution scans, 70...
Traumatic brain injury (TBI) often results in traumatic axonal and white matter (WM) damage, particularly to the corpus callosum (CC). Damage CC can lead impaired performance on neurocognitive tasks, but there is a high degree of heterogeneity impairment following TBI. Here we examined relation between microstructure function pediatric We used angular resolution diffusion-weighted imaging (DWI) evaluate structural integrity humans sample 32 children (23 males 9 females) with...
Abstract Recently, there has been a wealth of research into structural and functional brain connectivity, how they change over development. While we are far from complete understanding, these studies have yielded important insights human There is an ever growing variety methods for assessing each with its own advantages. Here review on the development and/or connectivity in both typically developing subjects neurodevelopmental disorders. Space limitations preclude exhaustive across all...
Traumatic brain injury (TBI) is the leading cause of death and disability in children can lead to a wide range impairments. Brain imaging methods such as DTI (diffusion tensor imaging) are uniquely sensitive white matter (WM) damage that common TBI. However, higher-level analyses using tractography complicated by decreased FA (fractional anisotropy) characteristic TBI, which result premature tract endings. We used newly developed autoMATE (automated multi-atlas extraction) method identify...
Background Smaller hippocampal volume in patients with posttraumatic stress disorder (PTSD) represents the most consistently reported structural alteration brain. Subfields of hippocampus play distinct roles encoding and processing memories, which are disrupted PTSD. We examined PTSD-associated alterations 12 subfields relation to global shape, clinical features. Methods Case-control cross-sectional studies U.S. military veterans (n = 282) from Iraq Afghanistan era were grouped into PTSD...
Results of neuroimaging datasets aggregated from multiple sites may be biased by site-specific profiles in participants' demographic and clinical characteristics, as well MRI acquisition protocols scanning platforms. We compared the impact four different harmonization methods on results obtained analyses cortical thickness data: (1) linear mixed-effects model (LME) that models random intercepts (LME
This review summarizes the last decade of work by ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance over 1,400 scientists across 43 countries, studying human brain in health and disease. Building on large-scale genetic studies that discovered first robustly replicated loci associated with metrics, has diversified into 50 working groups (WGs), pooling worldwide data expertise to answer fundamental questions neuroscience, psychiatry, neurology,...