A5065248056- Traumatic Brain Injury Research
- Posttraumatic Stress Disorder Research
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Functional Brain Connectivity Studies
- Suicide and Self-Harm Studies
- Resilience and Mental Health
- Healthcare professionals’ stress and burnout
- Musculoskeletal pain and rehabilitation
- Sleep and related disorders
- Cognitive Functions and Memory
- Sleep and Work-Related Fatigue
- Disaster Response and Management
- Neural dynamics and brain function
- Pediatric Pain Management Techniques
- Attention Deficit Hyperactivity Disorder
- Dementia and Cognitive Impairment Research
- Psychosomatic Disorders and Their Treatments
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Human-Automation Interaction and Safety
- Advanced Neuroimaging Techniques and Applications
- Automotive and Human Injury Biomechanics
- Health, Environment, Cognitive Aging
- Memory and Neural Mechanisms
Wake Forest University
2016-2025
W. G. (Bill) Hefner VA Medical Center
2015-2025
Mental Illness Research, Education and Clinical Centers
2016-2025
VA Mid-Atlantic Health Care Network
2020-2025
Durham VA Health Care System
2018-2025
Salisbury University
2019-2024
VA Salt Lake City Healthcare System
2024
Icahn School of Medicine at Mount Sinai
2024
University of Utah
2024
Edward Via College of Osteopathic Medicine
2014-2021
Use diffusion tensor imaging to investigate white matter alterations associated with blast exposure or without acute symptoms of traumatic brain injury (TBI).Forty-five veterans the recent military conflicts included 23 exposed primary TBI symptoms, 6 having mild TBI, and 16 unexposed blast.Cross-sectional case-control study.Neuropsychological testing metrics that quantified number voxel clusters altered fractional anisotropy (FA) radial diffusivity, axial regardless their spatial...
Abstract People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain this is accelerated biological aging, which associated with the accumulation of chronic diseases, disability, premature mortality. Using data from 2309 post-9/11 United States military veterans participated in VISN 6 MIRECC’s Post-Deployment Mental Health Study, we tested whether PTSD exposure were rate assessed using a validated DNA...
AbstractEmbedded validity measures support comprehensive assessment of performance validity. The purpose this study was to evaluate the accuracy individual embedded and reduce them most efficient combination. sample included 212 postdeployment veterans (average age = 35 years, average education 14 years). Thirty were initially identified as predictors Green's Word Memory Test (WMT) derived from California Verbal Learning Test-Second Edition (CVLT-II), Conners' Continuous Performance...
The United States (US) Department of Veterans Affairs (VA) Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC) Post-Deployment Health (PDMH) multi-site study examines post-deployment mental health in US military Afghanistan/Iraq-era veterans. includes the comprehensive behavioral characterization over 3600 participants genetic, metabolomic, neurocognitive, neuroimaging data for many participants. design also incorporates an infrastructure a repository to re-contact...
To evaluate the relationships among performance validity, symptom self-report, and objective cognitive testing.Combat Veterans (N = 338) completed a neurocognitive assessment battery several self-report measures assessing depression, posttraumatic stress disorder (PTSD) symptoms, sleep quality, pain interference, neurobehavioral complaints. All participants also two validity tests (PVTs) one stand-alone test (SVT) along with embedded SVTs.Results of an exploratory factor analysis revealed...
Objective: Embedded validity measures are useful in neuropsychological evaluations but should be updated with new test versions and validated across various samples. This study evaluated Wechsler Adult Intelligence Scale, 4th edition (WAIS-IV) Digit Span indicators post-deployment veterans.Method: Neurologically-intact veterans completed structured diagnostic interviews, the WAIS-IV, Medical Symptom Validity Test (MSVT), b as part of a larger study. The Noncredible group included individuals...
Mild traumatic brain injury (TBI) sustained in a deployment environment (deployment TBI) can be associated with increased severity of long-term symptom presentation, despite the general expectation full recovery from single mild TBI. The heterogeneity effects TBI on difficult for case-control design to capture. functional connectome is an approach robust that allows global measurement using common set outcomes. present study evaluates how differences relate remote presentation following...
The purpose of this study was to determine how sleep quality affects cognitive functioning in returning combat veterans after accounting for effects exposure, posttraumatic stress disorder (PTSD), and mild traumatic brain injury (mTBI) history.This a cross-sectional assessment evaluating PTSD, mTBI history, quality, neuropsychological functioning. One hundred nine eligible male Iraq/Afghanistan completed an consisting structured clinical interview, battery, self-report measures.Using partial...
Blast exposure is common among service members, but the chronic psychiatric effects associated with blast are not well-characterized independent of a resulting mild traumatic brain injury (TBI). This analysis evaluated whether severity was independently or exacerbated symptom report beyond posttraumatic stress disorder (PTSD) and TBI. Participants were Iraq Afghanistan combat veterans (N = 275; 86.55% male), 71.27% history exposure, 29.82% current diagnosis PTSD, 45.45% All participants...
Abstract The use of symptom validity tests (SVTs) is standard practice in psychodiagnostic assessments. Embedded measures are indices within self‐report measures. To date, no embedded SVTs have been identified the Posttraumatic Stress Disorder Checklist for DSM‐5 (PCL‐5). This research aimed to develop and validate PCL‐5 two samples veterans. Participants completed one prospective studies that included cognitive psychological tests. Study 1 were veterans ( N = 464) who served following...
An extensive library of symptom inventories has been developed over time to measure clinical symptoms traumatic brain injury (TBI), but this variety led several long-standing issues. Most notably, results drawn from different settings and studies are not comparable. This creates a fundamental problem in TBI diagnostics outcome prediction, namely that it is possible equate distinct tools inventories. Here, we present an approach using semantic textual similarity (STS) link scores across...
Cross-sectional and longitudinal studies in active duty veteran cohorts have both demonstrated that deployment-acquired traumatic brain injury (TBI) is an independent risk factor for developing post-traumatic stress disorder (PTSD), beyond confounds such as combat exposure, physical injury, predeployment TBI, pre-deployment psychiatric symptoms. This study investigated how resting-state networks differ between individuals who developed PTSD those did not following TBI. Participants included...
Objective: Mild traumatic brain injury (TBI) that occurs in a deployment environment is characteristically different from mild TBI outside of deployment. This study evaluated differential and interaction effects nondeployment on cognitive behavioral health outcomes. Research Method: Combat veterans (N = 293) who passed performance-validity measures completed the Mid-Atlantic MIRECC Assessment (MMA-TBI), Clinician-Administered Posttraumatic Stress Disorder (PTSD) Scale (CAPS-5),...
: To comprehensively characterize blast exposure across the lifespan and relationship to TBI.
COVID-19, caused by the SARS-CoV-2 virus, can lead to widespread neurological complications, including cognitive deficits and neurodegenerative symptoms, even in absence of significant structural brain abnormalities. The potential neuroprotective effects vaccination remain underexplored. Here, we demonstrate a psoralen-inactivated vaccine non-human primate model using resting-state magnetoencephalography (MEG), non-invasive neurophysiological recording technique with sub-millisecond temporal...