A5049284157- Traumatic Brain Injury Research
- Stroke Rehabilitation and Recovery
- Cardiac Arrest and Resuscitation
- Optical Imaging and Spectroscopy Techniques
- Neural and Behavioral Psychology Studies
- Transcranial Magnetic Stimulation Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Heart Rate Variability and Autonomic Control
- Functional Brain Connectivity Studies
- Cerebral Palsy and Movement Disorders
- Cardiovascular Effects of Exercise
- Resilience and Mental Health
- Cognitive Functions and Memory
- Long-Term Effects of COVID-19
- Musculoskeletal pain and rehabilitation
- Advanced Neuroimaging Techniques and Applications
- Memory and Neural Mechanisms
- Injury Epidemiology and Prevention
- Posttraumatic Stress Disorder Research
- Mental Health via Writing
- Balance, Gait, and Falls Prevention
- Advanced MRI Techniques and Applications
- Topic Modeling
- Attention Deficit Hyperactivity Disorder
- EEG and Brain-Computer Interfaces
Colorado State University
2017-2025
Craig Hospital
2025
University of Colorado Denver
2025
Foundation for Physical Medicine and Rehabilitation
2018-2021
National Institutes of Health
2021
Kennedy Krieger Institute
2016-2018
Johns Hopkins University
2016-2018
Foundation for the National Institutes of Health
2018
Johns Hopkins Medicine
2016-2017
University of Nevada, Reno
2013-2017
An increasing concern affecting a growing aging population is working memory (WM) decline. Consequently, there great interest in improving or stabilizing WM, which drives expanded use of brain training exercises. Such regimens generally result temporary WM benefits to the trained tasks but minimal transfer benefit untrained tasks. Pairing with neurostimulation may stabilize improve performance by enhancing plasticity and strengthening WM-related cortical networks. We tested this possibility...
Arterial spin labeling (ASL) has emerged as a technique for assessing mild traumatic brain injury (mTBI), it can noninvasively evaluate cerebrovascular physiology. To date, there is substantial variability in methodology and findings of ASL studies mTBI. While both increased decreased perfusion are reported after mTBI, more consistency emerging when examined with regard to symptomology. We evaluated 15 teenage athletes two six weeks sports-related concussion (SRC group) using...
Working memory (WM) permits maintenance of information over brief delays and is an essential executive function. Unfortunately, WM subject to age-related decline. Some evidence supports the use transcranial direct current stimulation (tDCS) improve visual WM. A gap in knowledge understanding mechanism characterizing these tDCS linked effects. To address this gap, we compared effects two montages designed on VWM performance. The bifrontal montage was stimulate heightened bilateral frontal...
Complex cognitive tasks such as visual working memory (WM) involve networks of interacting brain regions. Several neurotransmitters, including an appropriate dopamine concentration, are important for WM performance. A number gene polymorphisms associated with individual differences in task COMT, example, encodes catechol-o-methyl transferase the enzyme primarily responsible catabolizing prefrontal cortex. Striatal function, linked well habit learning, is influenced by Taq-Ia polymorphism...
Abstract Working memory (WM) training paired with transcranial direct current stimulation (tDCS) can improve executive function in older adults. The unclear mechanism of tDCS likely depends on intensity, and task relevant genetic factors (e.g., for WM: COMT val 158 met, DAT, BDNF 66 met). Higher intensity does not always lead to greater cognitive gains, polymorphisms may modulate tDCS-linked WM improvements. To evaluate these factors, 137 healthy adults provided DNA samples received Visual...
An extensive library of symptom inventories has been developed over time to measure clinical symptoms traumatic brain injury (TBI), but this variety led several long-standing issues. Most notably, results drawn from different settings and studies are not comparable. This creates a fundamental problem in TBI diagnostics outcome prediction, namely that it is possible equate distinct tools inventories. Here, we present an approach using semantic textual similarity (STS) link scores across...
Objective: Individuals with traumatic brain injury (TBI) often experience residual mobility deficits that can be improved treadmill and virtual reality interventions. However, previous studies have not measured the underlying neurophysiology during these interventions nor assessed if acquiring such data is feasible in a TBI population. Thus, primary purpose of this study was to assess feasibility using portable functional near-infrared spectroscopy (fNIRS) measure task task. Setting: Data...
This study examined functional connectivity of the default mode network (DMN) and brain-behavior relationships in a pilot cohort children with chronic mild to moderate traumatic brain injury (TBI).Compared uninjured peers, TBI demonstrated less anti-correlated between DMN right Brodmann Area 40 (BA 40). In TBI, more anomalous anti-correlated) BA was linked poorer performance on response inhibition tasks.Collectively, these preliminary findings suggest that may relate longterm outcomes pediatric TBI.
Occupational therapy practitioners use yoga in practice to achieve holistic care, and the American Therapy Association has provided guidance on of occupational therapy. For people with acquired brain injury (ABI), however, it is unknown whether affects performance.
Pediatric traumatic brain injury (TBI) is a heterogeneous condition, varying in both severity and sequelae. The long-term motor deficits following severe TBI requiring inpatient rehabilitation are better established than those milder forms of TBI. authors examined performance 2 12 months postinjury children without overt impairment using standard measures upper limb function the Physical Neurological Examination for Subtle Signs (PANESS). PANESS was sensitive to differences between with...
Abstract Adolescents who are clinically recovered from concussion continue to show subtle motor impairment on neurophysiological and behavioral measures. However, there is limited information brain–behavior relationships of persistent following clinical recovery concussion. We examined the relationship between performance functional connectivity brain in adolescents with a history concussion, status post‐symptom resolution, subjective return baseline. Participants included 27 were 29...
Poor response inhibition is a hallmark of pediatric traumatic brain injury (TBI). We assessed motor by measuring commission error rates on Simple (minimized cognitive demands) and Motivation (monetary reward) Go/No-Go tasks, comparing 17 children with chronic TBI (>1 year post-injury) 14 matched, uninjured peers. Using resting state functional magnetic resonance imaging (fMRI), we examined between-group differences in whole-brain intrinsic connectivity the network as derived from averaged...
Abstract Importance: Acquired brain injury (ABI) may result in deficits executive function (EF), which affects engagement occupations. Objective: To explore the impact of group yoga on EF people with ABI. Design: Single-arm pilot study preyoga assessments and postyoga (after 8 wk yoga). Setting: Yoga classes were completed within university buildings a college campus. Participants: Twelve participants chronic ABI (>6 mo post-ABI) recruited through convenience purposive strategies from...
Abstract Sensitive examination tools are needed to optimize evaluation after sports-related concussion. The Physical and Neurological Examination of Subtle Signs was preliminarily examined for sensitivity motor changes in a pilot cohort adolescents aged 13–17 yrs with A total 15 (5 female adolescents) concussion were evaluated up three times: within 2 wks injury, approximately 1 mo later (mean, 35 days between visits), those not recovered at the second visit, again clinical recovery 70 first...
This study examined the test–retest reliability of error-related negativity (ERN) and error positivity (Pe) amplitudes using a Flanker task in 118 neurotypical children 53 adults before after latency jitter adjustments. The ERN Pe was moderate for to strong adults. variability adjustment did not improve either group, suggesting that may be trait-like measure. For comparison purposes, stimulus-locked ERPs correct trials, yet weak incorrect trials.
Background: To date, no one has prospectively evaluated yoga intervention-induced changes in brain structure or function adults with acquired injuries (ABI). Thus, this study was conducted to test the feasibility of acquiring neuroimaging data from ABI before and after a intervention. Methods: This single-arm intervention that included 12 chronic (i.e., greater than 6 months post-injury) self-reported limitations balance. Neuroimaging were yoga. The completed once per week for eight weeks....
Background Each year, millions of Americans sustain acquired brain injuries (ABI) which result in functional impairments, such as poor balance and autonomic nervous system (ANS) dysfunction. Although significant time energy are dedicated to reducing impairment acute phase ABI, many individuals with chronic ABI have residual impairments that increase fall risk, decrease quality life, mortality. In previous work, we found yoga can improve adults (i.e., ≥6 months post-injury) ABI. Moreover, has...
Abstract Sports-related concussions (SRCs) pose significant challenges to college-aged athletes, eliciting both immediate symptoms and subacute cognitive motor function impairment. While most impairments resolve within weeks, athletes with repeat SRCs may experience heightened risk for prolonged recovery trajectories, future musculoskeletal injuries, long-term neurocognitive deficits. This includes impaired dual task performance altered neurophysiology that could persist across the lifespan...