Zheng Zhang

ORCID: 0000-0002-0902-7627
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Virus-based gene therapy research
  • Intraocular Surgery and Lenses
  • Advanced Fiber Laser Technologies
  • Acupuncture Treatment Research Studies
  • Solid State Laser Technologies
  • Mesenchymal stem cell research
  • Insect behavior and control techniques
  • Retinal Imaging and Analysis
  • Animal Virus Infections Studies
  • Myofascial pain diagnosis and treatment
  • Insect Resistance and Genetics
  • Membrane Separation Technologies
  • Bacillus and Francisella bacterial research
  • Biomedical and Chemical Research
  • 3D Printing in Biomedical Research
  • Laser-Matter Interactions and Applications
  • Quantum Dots Synthesis And Properties
  • Laser Design and Applications
  • Monoclonal and Polyclonal Antibodies Research
  • Advanced Drug Delivery Systems
  • Neurological disorders and treatments
  • Traditional Chinese Medicine Studies
  • Inhalation and Respiratory Drug Delivery
  • Urological Disorders and Treatments

Chinese University of Hong Kong
2025

Shenzhen Third People’s Hospital
2020-2025

Southern University of Science and Technology
2019-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025

Harbin University
2023-2025

Beijing Tongren Hospital
2011-2024

Capital Medical University
2024

University of California, San Diego
2021

Southwest University
2017

Jinzhou Medical University
2013

Abstract Minimizing the interaction of nanomedicines with mononuclear phagocytic system (MPS) is a critical challenge for their clinical translation. Conjugating polyethylene glycol (PEG) to regarded as an effective approach reducing sequestration by MPS. However, recent concerns about immunogenicity PEG highlight demand alternative low‐fouling polymers innovative coating materials nanoparticles. Herein, highly hydrophilic sulfoxide‐containing polymer—poly(2‐(methylsulfinyl)ethyl acrylate)...

10.1002/advs.202000406 article EN cc-by Advanced Science 2020-05-17

Abstract The emergence and rapid spread of the B.1.1.7 lineage (VOC-202012/01) SARS-CoV-2 variant has aroused global concern. N501Y substitution is only mutation in interface between RBD ACE2, raising concerns that its recognition by neutralizing antibodies may be affected. Here, we assessed activity binding affinity a panel 12 monoclonal against wild type mutant pseudovirus protein, respectively. We found neutralization most detected (10 out 12) were unaffected, although decreased...

10.1186/s12985-021-01554-8 article EN cc-by Virology Journal 2021-04-28

Several vaccines and immunization strategies, including inactivated vaccines, have proven effective in eliciting antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), providing an opportunity to characterize the antibody response. In this study, we investigated monoclonal responses elicited by wild-type SARS-CoV-2 vaccination compared those natural infection mRNA vaccination. The analysis showed that encoded biased germline genes were shared between vaccinated...

10.1093/jimmun/vkae056 article EN other-oa The Journal of Immunology 2025-02-24

Abstract Halide post‐treatment has emerged as a promising strategy for achieving pure‐blue emission in mixed‐halide perovskites by facilitating the incorporation of low‐solubility chloride while simultaneously passivating defects to enhance luminescence. Despite demonstrated success anion exchange, specific influence organic cations solutions remained insufficiently explored, limiting further optimization this technique. Here, role is investigated comparing two structurally similar halide...

10.1002/adom.202500544 article EN cc-by-nc-nd Advanced Optical Materials 2025-05-02

Time-dependent expression of proteins in ovary is important to understand oogenesis insects. Here, we profiled the proteomes developing ovaries from Bactrocera dorsalis (Hendel) obtain information about ovarian development with particular emphasis on differentially expressed (DEPs) involved oogenesis. A total 4838 were identified an average peptide number 8.15 and sequence coverage 20.79%. Quantitative proteomic analysis showed that a 612 196 mature ovaries, respectively. Furthermore, 153,...

10.3390/ijms18071379 article EN International Journal of Molecular Sciences 2017-06-30

Membrane fouling is a critical issue during the membrane filtration process. Photocatalytic membranes have been developed to address issue, although current approaches are mostly based on irradiation under UV light. In this study, we report preparation of photocatalytic with self-cleaning property visible light irradiation. A 3-(3,4-dihydroxyphenyl)lalanine (LDOPA) layer was first attached onto surface polysulfone (PSF) hollow fiber (HFM) via self-polymerization an immersion time 6 h/12 h/18...

10.1021/acs.iecr.8b05783 article EN Industrial & Engineering Chemistry Research 2019-02-05

Low-density lipoprotein cholesterol (LDL-C) is acknowledged as an independent risk factor (IRF) for atherosclerotic cardiovascular disease. Nevertheless, studies on the impact of LDL-C microvasculature are still scarce. The retina, abundant in microvasculature, can now be examined microvascular alterations through novel, non-invasive, and quantitative optical coherence tomography angiography (OCTA) technique.

10.1186/s12944-024-02287-7 article EN cc-by-nc-nd Lipids in Health and Disease 2024-09-16

<strong>Background:</strong> A defining characteristic of dystonia is its position-dependence. In cervical (CD), sensory tricks ameliorate head tremor (HT). But it remains unknown whether raising the arms alone has same impact. <strong>Methods:</strong> We analyzed data collected from patients enrolled by Dystonia Coalition. For 120 with HT, we assessed how their without touching changed HT severity. <strong>Results:</strong> Forty-eight out exhibited changes in severity when arms. These...

10.5334/tohm.623 article EN cc-by Tremor and Other Hyperkinetic Movements 2021-01-01

The aim of this study was to construct and characterize a novel recombinant human adenovirus vector expressing bone morphogenetic protein 2 (BMP2) green fluorescent (GFP). BMP2 gene in the plasmid pcDNA3-BMP2 sequenced restriction enzyme recognition sites were analyzed. Following mutagenesis using polymerase chain reaction (PCR), sequence after translation termination codon removed new added. mutated (BMP2+ gene) cloned into an shuttle obtain pShuttle cytomegalovirus (CMV)-BMP2+-internal...

10.3892/etm.2013.1162 article EN Experimental and Therapeutic Medicine 2013-06-17

Objective We compared wavefront aberration in pseudophakic eyes with 3 types of intraocular lenses (IOLs) implantation order to obtain an objective evaluation the optical quality these eyes. Methods This prospective study comprised 76 cataract patients (80 eyes) who had phacoemulsification surgery. The AcrySof MA30BM, Hydroview H60M, and Canon Staar, KS-1 were implanted at numbers 26, 27 each group respectively. Three months after surgery, aberrations measured un-dilated pupil using a...

10.3760/j:issn:0412-4081.2006.05.002 article EN 2006-05-01

Die Sprunggelenke stellen ein komplexes Konstrukt aus Knochen, Gelenken, Bändern und Muskeln dar. Sie sind essenzieller Bestandteil der Fußbewegung dienen Mobilität Stabilität beim Gehen. Dabei tragen sie das gesamte Körpergewicht daher besonders anfällig für zahlreiche Verletzungen. Kapsel-Band-Verletzungen am oberen Sprunggelenk (OSG) die häufigsten akuten Verletzungen des OSG können in eine Arthrose münden, zu den chronischen Erkrankungen zählt. Akupunktur kann sowohl akute Schmerzen als...

10.1055/a-1797-1390 article DE AkupunkturPraxis 2022-08-01

To the best of our knowledge, highly efficient tunable multi-wavelength laser properties Er 3+ , Yb Pr triple-doped BaLaGa 3 O 7 crystals are demonstrated for first time. The maximum output power 0.81W at ~2.7 µm has been obtained under absorbed pump 3.53 W with optical-to-optical conversion efficiency 22.9%. results demonstrate that sensitizer and deactivator can not only enhance effectively, but also suppress self-terminating effect . crystal is shown to be a promising candidate high...

10.2139/ssrn.4203250 article EN SSRN Electronic Journal 2022-01-01
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