A5101425278- Breast Lesions and Carcinomas
- Cancer and Skin Lesions
- Breast Cancer Treatment Studies
- Genetic factors in colorectal cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Prenatal Screening and Diagnostics
- Gastric Cancer Management and Outcomes
- Medical Imaging Techniques and Applications
- Parvovirus B19 Infection Studies
- Thyroid Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Sexual Differentiation and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Cancer Genomics and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Appendicitis Diagnosis and Management
- Pregnancy and preeclampsia studies
- Plant Pathogens and Fungal Diseases
- Cutaneous lymphoproliferative disorders research
- Renal Diseases and Glomerulopathies
- Cardiovascular Disease and Adiposity
- Body Contouring and Surgery
- Liver Disease Diagnosis and Treatment
Soonchunhyang University
2015-2025
Ansan University
2019-2025
Seoul National University Bundang Hospital
2024
Bucheon University
2020-2024
St. Vincent's Hospital
2020-2024
Catholic University of Korea
2014-2020
Cheil General Hospital and Women's Healthcare Center
2010-2020
Creative Commons
2018
Sungkyunkwan University
2011-2017
Samsung Medical Center
2011-2017
Abstract Elevation of total cell-free DNA (cfDNA) in patients with preeclampsia is well-known; however, whether this change precedes the onset symptoms remains inconclusive. Here, we conducted a nested case–control study to determine elevation cfDNA levels women who subsequently developed preeclampsia. Methylated HYP2 (m- ) were determined 68 blood samples collected from hypertensive disorders pregnancy, along 136 control samples, using real-time quantitative PCR. The measured m- converted...
Background Down syndrome (DS) is the most common known aneuploidy, caused by an extra copy of all or part chromosome 21. Fetal-specific epigenetic markers have been investigated for non-invasive prenatal detection fetal DS. The phosphodiesterases gene, PDE9A, located on 21q22.3, completely methylated in blood (M-PDE9A) and unmethylated placenta (U-PDE9A). Therefore, we estimated accuracy DS during first trimester pregnancy using this tissue-specific characteristic PDE9A....
Abstract Metaplastic carcinoma is a rare subtype of breast cancer that comprises histologically diverse malignancies. tends to have an aggressive clinical presentation, high metastatic potential, and more chances local recurrence, as compared with intraductal carcinoma. Although many pathologic finding been reported, our knowledge, there are few reports imaging findings for this type tumor. In study, we reviewed data 5 patients histopathologically proven metaplastic Multimodality including...
Purpose: Gastric adenoma (GA) is a premalignant lesion that precedes intestinal-type gastric carcinoma (GC). However, genetic progression mechanisms from GA to GC have not been clarified.Experimental Design: We performed whole-exome sequencing-based mutational analyses for 15 synchronous pairs of attached GAs and GCs.Results: There was no significant difference in the number driver mutations or copy-number alterations between GCs. Well-known TP53, APC, RNF43, RPL22 were recurrently detected...
Glomerulonephritis (GN) is characterized by podocyte injury or glomerular filtration dysfunction, which results in proteinuria and eventual loss of kidney function. Progress studying the mechanism GN, developing an effective therapy, has been limited absence suitable vitro models that can closely recapitulate human physiological responses. We developed a microfluidic glomerulus-on-a-chip device environment to construct functional barrier, with we investigated biological changes podocytes...
Firefighters are much more likely to be exposed traumatic events and consequently experience stress due the nature of their job. Moreover, firefighters at an increased risk repeated exposures events. Repeated in lead a greater likelihood suffering from stress-related mental health problems, including posttraumatic disorder (PTSD). Previous studies several countries have consistently reported higher prevalence rates PTSD among firefighters. In addition subjective suffering, is known adverse...
Invasive apocrine carcinoma (IAC) of the breast is a rare subtype malignancy. Its incidence not well known, but it approximately less than 1% to 4%. For these reasons, there are few reports and little information on radiologic appearance IAC. Furthermore, most case show malignant features which similar invasive ductal (IDC). We present IAC without typical feature mammography, ultrasonography (USG). Imaging findings computed tomography (CT), magnetic resonance imaging (MRI),...
Young Ae Lim, Jin Sook Oh, Seog Woon Kwon, Kye Chul Shin Kim, Kyung Un Park, Hyun Jun Heung Song, Duck Cho, Tae Hyoun Um, Mi Kyoung Lee, and Sang Moo Han, as Blood Bank Subcommittee, The Korean Association of External Quality Assessment Service. J Lab Med Qual Assur 2015;37:47-55. https://doi.org/10.15263/jlmqa.2015.37.2.47
Despite remarkable progression in the treatment and classification system of neuroendocrine tumor (NET), some questions have remained unanswered. The lack an established strategy for gastric NET is one problems. Because its paucity, not discussed independent, large-scaled prospective studies tends to be excluded from clinical trials. Moreover, a separate distinguished features render more complicated. Here, we present case female patient with G2 proliferation index multiple liver metastases....
Syphilis is a well-known sexually transmitted disease, and has multiple stages various symptoms. However, it difficult to diagnose syphilis in patients who may have no clinical Because of these reasons, there been several case reports on misdiagnosis syphilis. Generalized lymphadenopathy could be an indication diseases including malignancies or infections.We report secondary patient with generalized detected by fluorine-18-fluorodeoxy glucose positron emission tomography/computed tomography...
Shin Young Kim, Jong Cheol Seo, Yeon Ju Hyeon Park, Yoon Joo Lee, Hong Chun Ho Song, Kyung Jeon Jang, Jun and Hyun Min Yoon. Korean J Acupunct 2016;33:157-65. https://doi.org/10.14406/acu.2016.018
Background Sudden sensorineural hearing loss (SSNHL) has several aetiologies and may be a presenting symptom of vestibular schwannoma (VS).Objectives The aim this study was to investigate the recovery rate after steroid treatment prognostic factors SSNHL with VS.Materials Methods This retrospective observational wherein 32 patients VS who presented were analysed at tertiary referral centre. Hearing gain main outcome measures for intervention.Results Among 1698 SSNHL, found in 43 (2.5%)...
최근 국내에 난민이 급증하면서, 난민수용이 사회적 문제로 대두되고 있다. 성인 난민에 비해 난민아동은 강제이주 및 정착 과정에서 매우 취약한 상태에 놓이게 되나 이들에 대한 국내의 실증적 연구는 부족한 상황이다. 이에 본 국내 난민아동의 문화적응 스트레스와 우울의 관계에서 자아존중감의 조절효과를 검증하여 심리사회적 문제에 아동복지적 개입방안을 모색하는 것이 주 목적이다. 이를 위해 연구에서는 난민지원 NGO의 도움을 받아 임의표집 방식을 통해 만 6세 이상 18세 미만 70명의 아동을 표집하였고, 이들을 대상으로 2017년 7월부터 10월까지 약 4개월 동안 설문조사를 실시하였다. 그 결과 스트레스는 우울에 정적인 영향을 미쳤으며, 자아존중감은 보이는 것으로 나타났다. 특히 자아존중감이 높은 집단이 낮은 집단에 조절효과가 더 큰 이러한 결과를 바탕으로 우울을 감소시키고, 자아존중감 향상을 위한 심리적 지원방안을 논의하였다.