A5047394034- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Ion channel regulation and function
- Cardiac pacing and defibrillation studies
- Advanced MIMO Systems Optimization
- Wireless Communication Networks Research
- Cardiovascular Function and Risk Factors
- Advanced Wireless Communication Techniques
- Neuroscience and Neural Engineering
- Advanced Wireless Network Optimization
- Wireless Body Area Networks
- Telecommunications and Broadcasting Technologies
- Energy Harvesting in Wireless Networks
- Pulmonary Hypertension Research and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiovascular Syncope and Autonomic Disorders
- IoT Networks and Protocols
- Wireless Power Transfer Systems
- Heart Failure Treatment and Management
- Neuroscience and Neuropharmacology Research
- ECG Monitoring and Analysis
- Nonlinear Optical Materials Studies
- Receptor Mechanisms and Signaling
- Cardiovascular Health and Risk Factors
Shanghai Jiao Tong University
2016-2025
Shanghai Chest Hospital
2016-2025
University College London
2024
China Mobile (China)
2021
Beijing University of Posts and Telecommunications
2012-2020
Harbin Institute of Technology
2018
Chenzhou First People's Hospital
2017
DoCoMo Communications Laboratories Europe GmbH
2016
Wuhan University
2010-2015
Renmin Hospital of Wuhan University
2010-2015
The development of cardiac hypertrophy in response to increased hemodynamic load and neurohormonal stress is initially a compensatory that may eventually lead ventricular dilation heart failure. Regulator G protein signaling 5 (Rgs5) negative regulator protein-mediated by inactivating Gα(q) Gα(i), which mediate actions most known vasoconstrictors. Previous studies have demonstrated Rgs5 expresses among various cell types within mature showed high levels mRNA monkey human tissue Northern blot...
Facile detection of dopamine (DA) in biological samples for diagnostics remains a challenge. This paper reported an effective fluorescent sensor based on adenosine capped CdSe/ZnS quantum dots (A-QDs) highly sensitive DA human urine samples. In this assay, serves as capping ligand or stabilizer QDs to render high-quality dispersed water, and receptor attach onto the surface A-QDs. molecules can bind A-QDs via non-covalent bonding, leading fluorescence quenching due electron transfer. The...
Precision medicine calls for high demand of continuous, closed-loop physiological monitoring and accurate control, especially cardiovascular diseases. Cardiac optogenetics is promising its superiority cell selectivity time-space accuracy, but the efficacy relative to input light stimulus detected controlled separately by discrete instruments in vitro, which suffers from time retardation, energy consumption, poor portability. Thus, a highly integrated system based on implantable sensors...
Current guidelines for the optimal ablation strategy persistent atrial fibrillation(PerAF) remain unclear. While our previous RCT confirmed favorable prognosis of aggressive ablation, real-world evidence is still lacking. Among 4,833 PerAF patients undergoing catheter at 10 centers, two groups were defined: Regular Ablation(PVI-only or PVI plus anatomical ablation) and Aggressive Ablation(anatomical electrogram-guided ablation), with 1,560 each after propensity score(PS) matching. The...
ABSTRACT Background The evidence supporting additional linear ablation for persistent atrial fibrillation (PerAF) remains limited. This study investigates the mechanisms of intermediate tachycardia (AT), a transient state between PerAF and sinus rhythm (SR), during termination by catheter ablation, provides these mechanisms. Methods We analyzed 136 patients who converted to organized AT after in Extent‐AF study. Bi‐atrial activation mapping combined with entrainment was used identify...
Background Patients with heart failure reduced ejection fraction (HFrEF) and atrial fibrillation are mostly elderly patients, persistent (PerAF) multiple comorbidities tends to have a worse clinical prognosis. However, there is lack of randomised trial investigate the impact catheter ablation (CA) on outcomes in older PerAF combined HFrEF. Objective This study aims compare effects CA versus medical rate control (MRC) severity indicators Methods Older patients HFrEF underwent transthoracic...
Effect of Anxiety and Depression on the Recurrence Paroxysmal Atrial Fibrillation.Whether circumferential pulmonary vein ablation (CPVA) can alleviate anxiety depression symptoms is unknown effect recurrence atrial fibrillation (AF) after CPVA not clear.Two hundred ten patients with a diagnosis paroxysmal AF were admitted in study. Ninety-eight (CPVA group) 102 (medicine treated antiarrhythmic drugs, respectively. All followed up for 1 year. Zung Self-Rating Scale (SAS), (SDS), Short-Form...
Background N‐Methyl‐ d ‐aspartate receptors, also known as NMDA Receptors or NMDAR, are glutamate receptors that control calcium ion channels and regulate synaptic plasticity. Acute NMDAR activation can induce ventricular arrhythmias (VAs). However, the influence of chronic on cardiac electrophysiology remains unknown. Methods Results Wistar rats were randomly administered 0.9% saline (CTL group), (N plus MK801 (N+M group) for 14 days. Compared with CTL group, N group displayed elevated...
Abstract Pulsed field ablation is a novel approach to treating 33.5 million patients with atrial fibrillation and offers tissue‐specific advantage over conventional radiofrequency cryoablation. However, for complex structural targets in the heart, current electrodes often damage non‐target areas due inaccurate have employ electrical pulses amplitudes of several kilovolts. Herein, materials designs catheter‐integrated microelectrode sensors that can be used high‐precision low‐voltage pulsed...
The nonlinear absorption and optical limiting properties of a chiral polymer were investigated by employing Z-scan technique in femtosecond regime. Reverse saturable was observed the at 800 nm coefficient 5.97 cm/GW obtained irradiance 2.75 GW/cm2. versus input measured to meet linear increasing function, giving evidence two-photon induced excited-state existing. Particularly, shown possess large ratio (∼251) ground-state cross-section remarkable behavior achieved it.
The mobile data traffic is expected to grow beyond 1000 times by 2020 compared with it in 2010. In order support of capacity increase, improving spectrum efficiency one the important approaches. Meanwhile, Long Term Evolution (LTE)-Advanced, small cell and hotspot are scenarios for future network deployment increase from density domain. Under such environment, probability high Signal Interference plus Noise Ratio (SINR) region becomes larger which brings possibility introducing higher...
Circular RNAs (circRNAs) are an emerging class of RNA species that may play a critical regulatory role in gene expression control, which can serve as diagnostic biomarkers for many diseases due to their abundant, stable, and cell- or tissue-specific expression. However, the association between circRNAs atrial fibrillation (AF) is still not clear. In this study, we used sequencing data identify quantify circRNAs. Differential analysis identified 250 up- 126 down-regulated AF subjects compared...
Aims The aim of this study was to elucidate the effects regulator G-protein signaling 5 (Rgs5), a negative G protein-mediated signaling, on atrial repolarization and tachyarrhythmia (ATA) in mice. Methods Results In present study, incidence ATA were increased Rgs5−/− Langendorff-perfused mouse hearts during program electrical stimulation (PES) (46.7%, 7 15) burst pacing (26.7%, 4 compared with wild-type (WT) mice (PES: 7.1%,1 14; burst:7.1%,1 14) (P<0.05). And duration also shown longer...