A5070760380- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Essential Oils and Antimicrobial Activity
- Bacterial biofilms and quorum sensing
- Wound Healing and Treatments
- Urinary Tract Infections Management
- Diabetic Foot Ulcer Assessment and Management
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
University of Latvia
2002-2021
Latvian Biomedical Research and Study Centre
2002-2006
Abstract Background The Direct Repeat locus of the Mycobacterium tuberculosis complex (MTC) is a member CRISPR (Clustered regularly interspaced short palindromic repeats) sequences family. Spoligotyping widely used PCR-based reverse-hybridization blotting technique that assays genetic diversity this and useful both for clinical laboratory, molecular epidemiology, evolutionary population genetics. It easy, robust, cheap, produces highly diverse portable numerical results, as result...
To characterize the genetic basis of drug resistance in Mycobacterium tuberculosis Latvia, mutations involved rifampin (rpoB gene) and isoniazid (katG DNA from 19 drug-susceptible 51 multidrug-resistant M. complex isolates were analyzed. The most frequent rpoB gene found by Line Probe assay S531L (14 34 isolates), D516V (7 34), H526D (4 D516Y plus P535S 34) mutations. Direct sequencing seven with unclear results showed presence L533P mutation Q510H H526Y (1 double mutations, neither which...
Polyherbal formulations Jathyadi Thailam and Jatyadi Ghritam (JT) are used in Indian traditional medicine for diabetic chronic wounds, fistula, fissure, eczema, burn management. We aimed to investigate the antibacterial anti-inflammatory properties of crude hexane ethanol extracts JT formulations.Antibacterial activity was tested estimate minimum inhibitory concentrations (MICs) against nine reference bacterial strains, including one methicillin-resistant Staphylococcus aureus (MRSA)...
Objective. The most important virulence factor of Staphylococcus epidermidis is their capability to form a biofilm on the surfaces implanted medical devices. accumulative phase formation linked production intercellular adhesin encoded by icaADBC operon and accumulation-associated protein aap gene. aim study was investigate phenotypically genetically in clinical strains S. comparison with commensal strains. Material Methods. carried out 4 hospitals Riga, Latvia. In total, 105 isolated from...
Abstract Colonisation of gastrointestinal tract by extended spectrum beta lactamase (ESBL)-producing Gram-negative bacteria is a source for infections. The present work prospective study in Latvia aimed to determine the role two surgical profile wards transmission ESBL-producing bacteria. Differences between hospital were not analysed due low number patients. We have also determined correlation duration hospitalisation and risk ESBL colonisation. Tests made twice 136 patients — upon...