A5070096415- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Inflammatory Bowel Disease
- Amoebic Infections and Treatments
- Gastrointestinal Tumor Research and Treatment
- Neuroendocrine Tumor Research Advances
- Diagnosis and treatment of tuberculosis
- Foreign Body Medical Cases
- Tracheal and airway disorders
- IgG4-Related and Inflammatory Diseases
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Liver Disease and Transplantation
- Intestinal Malrotation and Obstruction Disorders
- Microscopic Colitis
- Intraperitoneal and Appendiceal Malignancies
- Parvovirus B19 Infection Studies
- Neonatal Health and Biochemistry
- Mosquito-borne diseases and control
- Gastrointestinal Bleeding Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Herpesvirus Infections and Treatments
Calderdale and Huddersfield NHS Foundation Trust
2022-2025
National Bureau of Animal Genetic Resources
2024
Calderdale Royal Hospital
2024
Huddersfield Royal Infirmary
2024
University of Plymouth
2023
Queen Mary University of London
2023
Newcastle upon Tyne Hospitals NHS Foundation Trust
2023
Freeman Hospital
2023
Peninsula Health
2023
Post Graduate Institute of Medical Education and Research
2012-2023
A large number of patients with chronic diseases like, cancer are cared for in homes by the family members India. The vital role that these play as "caregivers" is well recognized, however, burden on them poorly understood.To assess and to determine predictors caregivers patients.A cross-sectional, hospital based study conducted National Capital Territory Delhi.200 were selected systematic random sampling interviewed using standard, validated Hindi version Zarit Burden Interview.Univariate...
Background: Walled-off pancreatic necrosis (WOPN) is an important complication of acute pancreatitis that diagnosed by imaging modalities such as endoscopic ultrasound (EUS) or magnetic resonance (MRI), which can clearly visualize necrotic debris. The effectiveness abdominal (USG) in detecting solid debris WOPN not clear.
The study assessed physiological responses to induction high altitude first 3,500 m and then 4,200 compared the time course of acclimatization in two groups male volunteers. acutely inducted group was transported by aircraft (AI) 1 h, whereas gradually road (RI) 4 days. Baseline recordings basal cardiovascular, respiratory, blood gas variables were monitored at sea level as well on days 1, 3, 5, 7. Blood gases measured day 10 also. After 15 m, subjects road, measurements repeated except...
CASE REPORT A 45-year-old man presented to the Department of Medicine at our institution with 1 year noninflammatory pain in multiple joints. The had begun both knee joints, followed by low-back ache and neck, wrist, foot pain. There was no associated fever or swelling any joint. patient did not report history addiction illness but using fluoridated toothpaste. also lived a region India where problem fluorosis is endemic. On examination, we found his teeth brown strains rough, pitted enamel...
Summary: Altitude induced alterations in circulatory levels of PRL, LH, FSH and testosterone were studied seven eugonadal men at sea level (SL), during their stay high altitude (HA, 3500 m) a week after return to SL. The mean plasma PRL SL was 5.83 ± 1.7 SE ng/ml. On day one arrival HA, the values 7.81 1.81 9.21 1.64 ng/ml respectively not significantly different (p > 0.05) than initial values. However, on 18 increased < 0.01) 17.68 1.82 returned within days A significant decrease LH...
This study examined the prevalence and factors associated with Mycoplasma genitalium (MG) infection among HIV-positive women association between MG vaginal HIV-1 RNA shedding. attending an outpatient clinic in New Orleans, Louisiana, USA, from 2002 to 2005 were for a battery of sexually transmitted infections (STIs) underwent behavioural survey. A selected subset had measurement shedding analysed. Of 324 women, 32 (9.9%) infected MG. more likely be co-infected Neisseria gonorrhoeae Chlamydia...
Extrapancreatic necrosis (EPN) alone represents a subgroup of pancreatitis with better outcome than patients pancreatic parenchymal (PN). However, data on clinical significance EPN is limited, and the extent not known.Two hundred thirteen (136 [63.8%] males; mean age: 39.8 ± 13.2 years) acute were prospectively enrolled followed up till recovery or death. Contrast-enhanced computed tomography each patient was retrospectively evaluated for presence PN EPN, pleural effusion ascites. termed...
Arterial blood gas (ABG) parameters such as pH form part of multi-parameter scoring systems for predicting severe acute pancreatitis; however, literature on detailed evaluation ABG alone in this context is scarce.Patients with pancreatitis presenting to our unit between January 2012 and November 2013 were prospectively studied. analysis was done at admission development organ failure, any need intervention, mortality noted. The association various the failure or local complications,...
Background Hypocalcemia is a marker of poor prognosis in acute pancreatitis (AP) but the prognostic significance hypocalcemic tetany patients with AP has not been studied.We aimed to determine AP.Methods Consecutive who presented within 7 days symptoms were included.Serum calcium levels measured on admission and divided into two groups based presence (group 1) or absence hypocalcemia 2).Chvostek Trousseau signs sought all outcome measures compared between normocalcemia, asymptomatic...
1. Genetic improvement and widespread use of artificial selection may have impacted the genetic make-up Indian chicken breeds. The architecture contemporary population India needs to be assessed for future conservation programmes. This study utilised whole-genome sequences in 180 samples from 16 indigenous breeds, along with Red Jungle Fowl commercial White Leghorn.
ABSTRACT Background and Aims Severe alcohol‐associated hepatitis (SAH) is associated with high short‐term mortality, failure of response to corticosteroids a mortality ~70%–80% within 6 months. Granulocyte colony‐stimulating factor (G‐CSF) has been studied in steroid non‐responders; however, the data are limited. Methods This multicentre retrospective cohort study. The study period was from January 2016 November 2023. SAH defined as (ICD‐10‐CM codes) serum bilirubin ≥ 5.0 mg/dL INR 1.5....
A 30-year-old female presented with progressively increasing dysphagia associated loss of appetite and weight. Upper gastrointestinal endoscopy revealed a polypoidal ulcerated lesion in the mid esophagus endoscopic biopsies being inconclusive [Figure 1]. An ultrasound (EUS) asymmetrical thickening esophageal wall stratification 2] as well fat planes right pulmonary artery 3]. No mediastinal lymphadenopathy was noted. EUS guided fine-needle aspiration (FNA) 4] yielded caseous material...
Methotrexate is an antimetabolite commonly used in clinical practice for a variety of indications ranging from rheumatoid arthritis and other connective tissue disorders to high dose regimens many malignancies. This folate antagonist has got spectrum toxicities among which gastrointestinal effects predominate . Lung injury well described but rare event been reported most often patients who have on long term oral therapy rheumatic disorders. Acute lung patient receiving regimen haematological...
Dengue infection is one of the most common viral hemorrhagic fevers seen in tropical countries, including India. Its presentation varies from an acute self-resolving febrile illness to life-threatening shock and multiorgan dysfunction leading death. Neurological presentations are uncommon limited case reports only. Most neurological manifestations being encephalitis, inflammatory demyelinating polyradiculoneuropathy, transverse myelitis, disseminated encephalomyelitis. Hypokalemic...
•This study identified significant variation in the management of NAFLD UK.•Non-invasive fibrosis assessment was only performed 27.9% patients with suspected NAFLD.•Greater emphasis on associated cardiometabolic risk factors is warranted individuals NAFLD.•Fibrosis evaluation and were more likely within hospitals a multidisciplinary service.•Further work needed to align guideline recommendations real-world practice care. Background & AimsNon-alcoholic fatty liver disease (NAFLD)...
Abstract Gastric tuberculosis is very rare and usually associated with pulmonary tuberculosis. Endoscopically, it resembles peptic ulcer disease or malignancy. We present a 28-year-old female who had submucosal lesion in the body of stomach that mimicked tumor. Endoscopic ultrasound guided fine needle aspiration yielded caseous material, cytological examination confirmed diagnosis
Hookworms are recognised as a cause of iron-deficiency anaemia in endemic areas. They are, however, often not considered the differential diagnosis overt gastrointestinal bleeding. We report endoscopic hookworms bleeding three patients, two whom had frank haemorrhage with one presenting hypovolemic shock. Hookworm infestation is an important treatable tropical countries.
Abstract Background Tofacitinib, filgotinib, and upadacitinib are Janus Kinase inhibitors (JAKi) effective in inducing maintaining remission moderate-to-severe ulcerative colitis (UC). Limited data exists regarding outcomes patients on a second JAKi after prior treatment failure. Here we describe the effectiveness of induction with cohort UC patients. Methods In this retrospective study, from 20 UK hospitals treated were included. Clinical endpoints, as defined Table 1, assessed at week 8....
We aim to perform a multicenter retrospective cohort study determine if elevated serum lipase determines clinical outcomes in patients with coronavirus disease 2019 (COVID-19).Several cases of acute pancreatitis (AP) have recently been reported association severe respiratory syndrome 2 (SARS-CoV-2) infection. Most the evidence is based on values without objective demonstration pancreatic inflammation or necrosis.A population-based, multicenter, utilizing TriNetX was performed obtain...
Gallstone disease is a recognized complication of bariatric surgery. Subsequent management choledocholithiasis may be challenging due to altered anatomy which include Roux-en-Y gastric bypass (RYGB). We conducted retrospective service evaluation study assess the safety and efficacy endoscopic ultrasound-directed transgastric retrograde cholangiopancreatography (EDGE) in patients with RYGB anatomy.All who underwent EDGE for after at two tertiary care centers United Kingdom between January...