A5101469567- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Esophageal Cancer Research and Treatment
- Autophagy in Disease and Therapy
- Gastric Cancer Management and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gastrointestinal Tumor Research and Treatment
- Ocular Oncology and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Genetic Neurodegenerative Diseases
- Neuroendocrine Tumor Research Advances
- Pediatric health and respiratory diseases
- Lung Cancer Research Studies
- Metastasis and carcinoma case studies
- Radiation Dose and Imaging
- Birth, Development, and Health
- Cancer, Hypoxia, and Metabolism
- Traumatic Brain Injury and Neurovascular Disturbances
- Hemodynamic Monitoring and Therapy
- Inflammasome and immune disorders
- Medical Imaging Techniques and Applications
- Traumatic Brain Injury Research
- Sepsis Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Suicide and Self-Harm Studies
Nanjing Medical University
2015-2025
Jiangsu Province Hospital
2015-2025
Anhui Mental Health Center
2025
Anhui Medical University
2025
Suzhou Municipal Hospital
2023
Ruijin Hospital
2021
Shanghai Jiao Tong University
2021
Southern Medical University
2018
Nanfang Hospital
2018
Tianjin University of Science and Technology
2017
Aims: The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, which is activated by reactive oxygen species (ROS) and repressed autophagy, has been identified as a novel agent of pulmonary fibrosis. Angiotensin II (AngII), the bioactive pro-oxidant in renin–angiotensin system, aggravates lung However, effect AngII on NLRP3 inflammasome autophagy fibrosis remains unknown. This study investigates potential link between AngII-induced regulation inflammasome/IL-1β axis...
Background Preoperative local-regional tumor staging of gastric cancer (GC) is critical for appropriate treatment planning. The comparative accuracy multiparametric MRI (mpMRI) versus dual-energy CT (DECT) GC not known. Purpose To compare the diagnostic personalized mpMRI with that DECT T and N in patients receiving curative surgical intervention. Materials Methods Patients who underwent before gastrectomy lymphadenectomy were eligible this single-center prospective noninferiority study...
Recent studies suggested that the gray-white matter ratio (GWR) determined from brain computed tomography (CT) scans may be a reliable predictor of poor neurological outcomes. The aim study was to evaluate association between GWR and outcomes in adult comatose cardiac arrest (CA) survivors Chinese.A total 58 CA patients who had CT within 72 h resuscitation January 2011 December 2015 were included this single-center retrospective study. Gray white attenuations (Hounsfield units) measured,...
Cigarette smoking is acknowledged as the major risk factor of pulmonary fibrosis. Angiotensin (Ang) II has been reported to aggravate smoking-induced lung fibrosis, whereas effect Ang-(1-7) on smoking-related fibrosis remains unknown. The autophagy, being activated by reactive oxygen species (ROS), identified a novel mechanism However, whether autophagy involved in regulation still needs investigation. Here, we aim investigate and ROS. In vivo, was constantly infused into passive rats for 8...
Objective To explore the prevalence of suicidal ideation (SI) and attempt (SA) in inpatients with childhood adolescent depressive disorders relationship between triglyceride/high-density lipoprotein cholesterol (TG/HDL-C), total cholesterol/high-density (TC/HDL-C) ratios SI, SA. Methods A study was conducted involving 515 pediatric patients diagnosed at Third People’s Hospital Fuyang. This research primarily focused on gathering basic demographic clinical data. Through employing methods such...
sophageal cancer is the fourth most common in China with five-year survival rates ranging from 15% to 40% (1-3).Patients early-stage esophageal are usually treated endoscopic submucosal dissection (ESD) or esophagectomy.However, for patients unresectable advanced who cannot tolerate esophagectomy, chemoradiation therapy (CRT) a priority.CRT prolonged lifetime of many cancer, but some benefit it, which depends on patients' response (4).Meanwhile, side effects caused by CRT including bone...
ABSTRACT Objective To construct a prediction model for fetal growth restriction (FGR) during the first trimester of pregnancy and evaluate its screening performance. Methods This was prospective cohort study singleton pregnancies that underwent routine ultrasound at 11 to 13 + 6 weeks Affiliated Suzhou Hospital Nanjing Medical University between January 2019 April 2022. Basic clinical information, indicators serum biomarkers pregnant women were collected. Fetal weight assessment based on...
Autophagy is a highly conserved cellular process in eukaryotic cells. The triterpenoidal saponin fraction (<italic>Conyza blinii</italic> saponins, CBS) isolated from medicinal plant <italic>Conyza H.Lév. dual-targeting autophagy inhibitor for HeLa
Previous studies have demonstrated that apparent diffusion coefficient (ADC) values measured by magnetic resonance imaging prognostic value in patients with esophageal squamous cell carcinoma (ESCC). However, the role of ADC needs to be validated a cohort Chinese ESCC patients. This study assessed predicting outcome treated only chemoradiation People's Republic China.Seventy-three local advanced were retrospectively analyzed this study; none underwent surgery before or after chemoradiation....
To find the predictors for persistent inflammation-immunosuppression catabolism syndrome in ICU surgical septic patients.Single center observation study.Inclusion: 1) patients ≥18, 2) admitted to after major surgery or transferred within 48 hours diagnosis of sepsis following definition sepsis-3.0. Exclusion: pregnant lactating patients, with severe immune deficiency, 3) that expired 14 days sepsis.A total 169 participants were included. After propensity score matching, PICS found have...
To evaluate the clinical value of plain magnetic resonance (MR) imaging (including cholangiopancreatography, MRCP) and coronal liver acquisition with volume acceleration (LAVA) technique in diagnosis preoperative assessment malignant low-level biliary obstruction. Forty-one patients confirmed obstruction were examined by MR, MRCP LAVA techniques. Group 1, MR MRCP); group 2, LAVA; 3, LAVA. Assessments included positioning, qualitative evaluation. The results compared pathological, endoscopic...
The treatment strategies and prognosis for gastroenteropancreatic neuroendocrine tumors were associated with tumor grade. Preoperative predictive grading could be of great benefit in the selection options patients. However, there is still a lack effective non-invasive to detect gastrointestinal (GI-NETs) preoperatively.The data on 147 consecutive GI-NETs patients was retrospectively collected from January 1, 2012, December 31, 2019. Logistic regression used construct model using preoperative...
Background There is increased interest in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for predicting the outcomes of patients with advanced esophageal cancer. Purpose To explore whether DCE-MRI histogram parameters can predict 12-month progression-free survival (PFS) squamous carcinoma receiving concurrent chemoradiation therapy (CRT). Material and Methods This retrospective study enrolled 134 who were CRT. The pre-CRT (median, mean, SD, skewness, kurtosis, 10th 90th...
Objective: To explore the mechanism of angiotensin-converting enzyme 2 (ACE2) overexpression improving collagen synthesis in lung. Methods: Lung fibroblasts mice over-expressing ACE2 and wild type (WT) were cultured vitro divided into 5 groups: WT-control, WT-AngiotensinⅡ (AngⅡ), ACE2(+ /+) -control, -AngⅡ -AngⅡ+ A779. The protein relative expression levels ACE2, Ⅰ, nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4), nucleotide binding oligomerization domain-like receptor family...
Objective To summarize the CT imaging features of peritoneal metastasis gastric cancer (GC). Methods The retrospective cross-sectional study was conducted. The clinicopathological data 78 GC patients with who were admitted to First Affiliated Hospital Nanjing Medical University from January 2013 September 2016 collected. All underwent plain and enhanced scans CT, converted multiplanar reformation (MPR) maximum intensity projection (MIP). Observation indicators: (1) primary lesion GC;...