A5004144742- Parkinson's Disease Mechanisms and Treatments
- Cancer-related molecular mechanisms research
- Gastric Cancer Management and Outcomes
- MicroRNA in disease regulation
- RNA modifications and cancer
- Nutrition and Health in Aging
- Cancer Immunotherapy and Biomarkers
- Neuroscience and Neuropharmacology Research
- Ovarian cancer diagnosis and treatment
- Diet and metabolism studies
- Natural product bioactivities and synthesis
- Circular RNAs in diseases
- Inflammatory Biomarkers in Disease Prognosis
- Quantum Dots Synthesis And Properties
- Neurological disorders and treatments
- Cancer-related gene regulation
- Frailty in Older Adults
- RNA Research and Splicing
- Cancer, Lipids, and Metabolism
- Photodynamic Therapy Research Studies
- Cancer Mechanisms and Therapy
- Immune cells in cancer
- Anesthesia and Neurotoxicity Research
- Inflammasome and immune disorders
- Intensive Care Unit Cognitive Disorders
Zhejiang Chinese Medical University
2024-2025
Wenzhou Medical University
2017-2025
Harbin Medical University
2018-2025
Hangzhou First People's Hospital
2022-2025
University at Buffalo, State University of New York
2022-2025
Liaoning University of Traditional Chinese Medicine
2022-2025
Westlake University
2025
Third Affiliated Hospital of Harbin Medical University
2018-2025
Shihezi University
2025
Army Medical University
2018-2025
Ultra-high-performance concrete (UHPC) is a recently developed material which has attracted considerable attention in the field of civil engineering because its outstanding characteristics. One key factors design compressive strength (CS) UHPC. As one most potent tools artificial intelligence (AI), machine learning (ML) can accurately predict concrete’s mechanical properties. Hyperparameter tuning crucial ensuring prediction model’s reliability. However, it complex work. The purpose this...
Background and Purpose— Dysregulation of the miR-15a/16-1 cluster in plasma has been reported patients with stroke as a potential biomarker for diagnostic prognostic use. However, essential role therapeutic ischemic are poorly understood. This study is aimed at investigating regulatory brain injury insight mechanisms. Methods— Adult male knockout wild-type mice, or adult C57 BL/6J mice injected via tail vein miR-15a/16-1–specific inhibitor (antagomir, 30 pmol/g), were subjected to 1 hour...
Quantum dot-based up-conversion photodetector, in which an infrared photodiode (PD) and a quantum dot light-emitting diode (QLED) are back-to-back connected, is promising candidate for low-cost imaging. However, the huge efficiency losses caused by integrating PD QLED together hasn't been studied sufficiently. This work revealed at least three origins losses. First, unit usually didn't under optimal conditions same time. Second, potential barriers traps interconnection between units induced...
Abstract Background Sarcopenia is an age-related syndrome that may have negative impact on surgical outcomes and long-term survival of patients with gastric cancer. Serum creatinine/cystatin C (Cr/CysC) ratio has attracted attention as a surrogate marker for sarcopenia but not been adequately studied in The purpose this study was to investigate the validity serum Cr/CysC predictor sarcopenia, evaluate statistical cut-off value, assess relationship between prognosis Methods We retrospectively...
6G will be characterized by extreme use cases, not only for communication, but also localization, and sensing. The cases can directly mapped to requirements in terms of standard key performance indicators (KPIs), such as data rate, latency, or localization accuracy. goal this paper is go one step further map these KPIs on signals, hardware architectures, deployments. Based this, system solutions identified that support several simultaneously. Since there are ways meet the KPIs, no unique...
Background: Levodopa remains the most effective drug in treatment of Parkinson's disease. However, long-term administration levodopa induces motor complications, such as levodopa-induced dyskinesia. The mechanisms underlying dyskinesia are not fully understood. Methods: In this study, we prepared methyl ester (LDME)/benserazide-loaded nanoparticles, which can release LDME and benserazide a sustained manner. Dyskinesia was induced rats by repeated then treated with plus or same dose...
Abstract Epithelial ovarian carcinoma (EOC) is the most lethal gynecologic malignancy. However, molecular mechanisms remain unclear. In this study, we found that miR-146b was downregulated in EOC and its expression level negatively correlated with pathological staging. Follow-up functional experiments illustrated overexpression of significantly inhibited cell migration invasion, increased proliferation, but it also improved response to chemotherapeutic agents. Mechanistically, demonstrated...
Abstract Herein, a coordination trap strategy is proposed for constructing stimulus‐responsive phosphorescent perovskites. Hydroxyl groups are selected as and introduced into benzylamine hydrochloride of Cd‐based perovskite. The resulting two‐dimensional (2D) perovskite (C 7 H 10 NO) 2 CdCl 4 ·H O (H1) exhibits blue fluorescence at 405 nm green phosphorescence 482 under 365 excitation. After introducing guest Mn 2+ , due to the passivation defects, doped H1 (H1‐M) achieves orange ( λ = 615...
Pyroptosis, which is a novel form of immunogenic cell death, plays vital role in antitumor therapy. Zirconium-based metal–organic frameworks (Zr-MOFs) have been applied various treatments. However, the intrinsic these pyroptosis has yet to be determined. Here, Zr-MOF-based nanosystem (DOX@Zr-MOF) was constructed by loading Zr-MOF nanoparticles with chemotherapeutic drug doxorubicin (DOX) synergistically trigger cancer pyroptosis. We found that DOX@Zr-MOF rapidly triggered via activation...