A5101630114- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Orthopaedic implants and arthroplasty
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Sports injuries and prevention
- Shoulder Injury and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Osteoarthritis Treatment and Mechanisms
- Bone and Joint Diseases
- Mesenchymal stem cell research
- Venous Thromboembolism Diagnosis and Management
- Cancer-related molecular mechanisms research
- Periodontal Regeneration and Treatments
- Anesthesia and Pain Management
- Reconstructive Surgery and Microvascular Techniques
- Blood transfusion and management
- Hip and Femur Fractures
- Shoulder and Clavicle Injuries
- Ferroptosis and cancer prognosis
- Pomegranate: compositions and health benefits
- Bioactive Compounds in Plants
- Macrophage Migration Inhibitory Factor
- Spinal Cord Injury Research
Qingdao University
2014-2025
Affiliated Hospital of Qingdao University
2014-2025
Hebei University
2024
Rothman Institute
2017-2020
Thomas Jefferson University
2017-2020
Rothman Orthopaedics
2020
Affiliated Hospital of Guizhou Medical University
2019
Guiyang Medical University
2019
Zhaotong University
2005
This study aimed to compare the efficacy and safety of aspirin, rivaroxaban low-molecular-weight heparin (LMWH) for post total knee arthroplasty (TKA) deep vein thrombosis (DVT) prophylaxis. Between July 2011 2013, a prospective randomized controlled trial was performed on 324 patients with osteoarthritis who underwent primary unilateral TKA. Twelve hours after surgery, Group A given oral at dose 10 mg/day. B subcutaneous LMWH 4000 AxaIU (0.4 ml)/day C aspirin 100 All three groups were...
Background: Most studies of allograft versus autograft for anterior cruciate ligament reconstruction have been bone–patellar tendon–bone; outcome reports evaluating with hamstring tendon are rare. Purpose: This study was undertaken to compare the clinical arthroscopic allograft. Study Design: Randomized controlled trial; Level evidence, 2. Methods: Between 2000 and 2004, 208 patients who met inclusion exclusion criteria were prospectively randomized into (n = 104) or groups. All allografts...
Mechanical stress plays an important role in the initiation and progression of osteoarthritis. Studies show that excessive mechanical can directly damage cartilage extracellular matrix shift balance chondrocytes to favor catabolic activity over anabolism. However, underlying mechanism remains unknown. MicroRNAs (miRNAs) are emerging as regulators osteoarthritis pathogenesis. We have found loading up-regulated microRNA miR-365 growth plate chondrocytes, which promotes chondrocyte...
Background: Most studies on grafts for anterior cruciate ligament (ACL) reconstruction (ACLR) have been of autografts or nonirradiated allografts with a single-bundle (SB) technique. Outcome reports evaluating anatomic double-bundle (DB) ACLR hamstring tendon autograft versus irradiated allograft are rare. Purpose: To compare the clinical outcomes arthroscopic DB allograft. Study Design: Randomized controlled trial; Level evidence, 2. Methods: Between 2008 and 2009, total 107 patients...
Inflammatory cytokines are crucial factors in the onset of osteoarthritis (OA). The pro-inflammatory cytokine, interleukin-1β (IL-1β), is capable stimulating a few cartilage degradation mediators and importance to pathogenesis OA. It has been demonstrated that hydrogen sulfide (H2S) exerts an inhibitory effect on inflammation. Thus, present study, we aimed investigate therapeutic effects H2S For this purpose, vitro model inflammation was created. Human OA chondrocytes were cultured...
Abstract Background Tumor microenvironment (TME) plays an important role in malignant tumors. Our study aimed to investigate the effect of TME and related genes osteosarcoma patients. Methods Gene expression profiles clinical data patients were downloaded from TARGET dataset. ESTIMATE algorithm was used quantify immune score. Then, association between score prognosis studied. Afterward, a differential analysis performed based on high- low-immune scores determine TME-related genes....
Morocco is rich in Mississippi Valley Type (MVT) copper deposits. Currently, geochemical surveying being conducted the Goulmima region pursuit of breakthroughs mineral exploration. This paper focuses on delineation prospecting targets area based ongoing 1:100,000 survey work Morocco. The study employs compositional data transformation to perform isometric log-ratio (ilr) transformations raw data, followed by Spectrum-Area (S-A) fractal processing, and then uses Random Forest (RF) algorithm...
Introduction Elderly patients with impaired intrinsic capacity are at increased risk for delayed or suboptimal recovery from surgery. S-ketamine has been proven to improve postoperative quality. However, limited trials studying the quality in elderly capacity. Therefore, objective of this study was evaluate impact on following total knee arthroplasty. Methods and analysis This is a single-centre, randomised, double-blind, placebo-controlled trial. Participants undergoing arthroplasty will be...
Relative young and more active patients with osteoarthritis (OA) of the isolated medial femorotibial compartment in conjunction anterior cruciate ligament (ACL) deficiency are difficult to treat. The aim this study was explore early clinical outcomes combined Oxford unicompartmental knee arthroplasty (UKA) ACL reconstruction for presenting OA compartment. Twenty-eight were included into study. All treated by UKA reconstruction. Plain radiographs antero-posterior lateral view long-leg...
Investigating the effectiveness of S-ketamine in reducing rebound pain (RP) following total knee arthroplasty. This study was a randomized, double-blind, placebo-controlled trial involving 356 adult patients undergoing Patient enrollment occurred between April and October 2023, with in-person follow-up assessments conducted from admission to 3 days post-surgery. Participants were randomly assigned group (n = 178) placebo 178). In group, participants received continuous intraoperative...
Introduction Frailty is characterized by a decline in multiple physiological systems, increasing vulnerability to stressors such as surgery and anesthesia. A intrinsic capacity common among elderly populations has been demonstrated be predictor of frailty community-dwelling seniors. However, the relationship between preoperative postoperative surgical patients remains unclear. Methods This study single-center, prospective, cohort study. The will recruit participants aged 60 years above who...
Persistent SARS-CoV-2 infection in immunocompromised patients creates a unique environment for the accumulation of mutations linked to immune evasion. This is due prolonged virus-host interaction, coupled with effects diminished selective pressures resulting from suboptimal adaptive immunity. In this study, we investigated viral evolution and escape during 2.5-year persistent patient history multiple myeloma rheumatoid arthritis on B cell depleting therapy. Sequencing virus isolate 899 days...
// Xin-Xing Zhu 1, 2, * , Ya-Wei Yan Chun-Zhi Ai 1 Shan Jiang Shan-Shan Xu Min Niu 3 Xiang-Zhen Wang 4 Gen-Shen Zhong 5 Xi-Feng Lu 6 Yu Xue 7 Shaoqi Tian 8 Guangyao Li 9 Shaojun Tang 10 Yi-Zhou Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China 2 Key Laboratory of Optoelectronic Devices and Systems Ministry Education College Engineering, Department Statics, University Wisconsin-Madison, Madison, WI, USA Maternal Child Health Hospital Nanshan District, The First...