A5060087499- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Lipoproteins and Cardiovascular Health
- Diverticular Disease and Complications
- Cancer, Lipids, and Metabolism
- Inflammatory mediators and NSAID effects
- Osteoarthritis Treatment and Mechanisms
- Innovations in Medical Education
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal motility and disorders
- Economic and Financial Impacts of Cancer
- Cancer Treatment and Pharmacology
- Colorectal Cancer Treatments and Studies
- Global Cancer Incidence and Screening
- Corporate Finance and Governance
- Congenital gastrointestinal and neural anomalies
- Diversity and Career in Medicine
- Hernia repair and management
- Gastroesophageal reflux and treatments
- Breast Lesions and Carcinomas
- Cancer Risks and Factors
- Pelvic floor disorders treatments
- Otitis Media and Relapsing Polychondritis
Indian Institute of Technology Roorkee
2025
Washington State University Spokane
2018-2025
Georgia Highlands College
2019-2025
Swansea University
2025
HLL Lifecare (India)
2021
Kadlec Regional Medical Center
2021
Washington State University
2021
Virginia Mason Medical Center
2016-2019
University of Washington
2017-2019
Swedish Medical Center
2019
Abstract Objective Behçet's disease ( BD ) is a chronic, relapsing, inflammatory vascular with no pathognomonic test. Low sensitivity of the currently applied International Study Group ISG clinical diagnostic criteria led to their reassessment. Methods An Team for Revision Criteria (from 27 countries) submitted data from 2556 clinically diagnosed patients and 1163 controls ‐mimicking diseases or presenting at least one major sign. These were randomly divided into training validation sets....
Statins are cholesterol-lowering drugs with pleiotropic activities including inhibition of isoprenylation reactions and reduction signals driving cell proliferation survival responses. The objectives this study were to examine the effects statins on breast cancer cells, both in vitro vivo, begin determine their mechanism action. We evaluated growth, phosphoprotein signaling intermediates, survival/apoptosis regulators, cycle activated transcription factors. also examined vivo effect statin...
Adding modified FOLFOX6 (folinic acid, fluorouracil, and oxaliplatin) after chemoradiotherapy lengthening the chemoradiotherapy-to-surgery interval is associated with an increase in proportion of rectal cancer patients a pathological complete response.The purpose this study was to analyze disease-free overall survival.This nonrandomized phase II trial.The conducted at multiple institutions.Four sequential groups stage or III were included.All received 50 Gy radiation concurrent continuous...
Background: Intra-articular corticosteroids are a mainstay in the treatment of knee osteoarthritis, and clinical trials, they demonstrate large initial analgesic effect that wanes over one to four weeks with rapid efflux drug from joint. The present study was undertaken determine if FX006, an extended-release formulation triamcinolone acetonide, can provide pain relief is superior current standard care, immediate-release acetonide. Methods: In this Phase-2, double-blind, multicenter study,...
Purpose Magnetic resonance imaging (MRI) is an important tool for characterizing invasive breast cancer but has proven to be more challenging in the setting of ductal carcinoma situ (DCIS). We investigated whether MRI features DCIS reflect differences biology and pathology. Patients Methods Forty five 100 patients with biopsy-proven who underwent had sufficient tissue characterized by pathologic (nuclear grade, presence comedo necrosis, size, density disease) immunohistochemical (IHC)...
Abstract Background: Preclinical studies have shown the anticancer potential of HMG-CoA reductase enzyme inhibitors (statins), whereas epidemiologic remain controversial. Because lipophilic statins show preclinical activity against hormone receptor [estrogen (ER)/progesterone (PR)]–negative breast cancer models, we explored phenotype cancers that arise in statin users. Methods: We did a retrospective cohort analysis via electronic pharmacy records from Kaiser Permanente Northern California...
Background and Objectives. Systemic chemotherapy administered prior to cytoreductive surgery hyperthermic intraperitoneal (HIPEC) for peritoneal mucinous adenocarcinoma of appendiceal origin (PMCA) is associated with a significant rate histological response. The impact preoperative systemic (PSC) on tumor burden, completeness cytoreduction, perioperative complications unknown. Methods. We analyzed prospectively collected data from our HIPEC database. Thirty-four patients PMCA were recruited...
Transanal endoscopic microsurgery, a minimally invasive procedure for treatment of early-stage rectal cancer, carcinoid tumors, and adenomas, is shown to be safe with very low perioperative morbidity.We aimed compare the outcomes transanal microsurgery at large volume tertiary care center existing literature.We retrospectively reviewed prospectively collected database 325 procedures looked risk factors associated complications. Indications included adenocarcinomas, carcinoids.Procedures were...
Rectal carcinoids are often inadequately resected by snare excision during colonoscopy. Transanal endoscopic microsurgery is a minimally invasive procedure with low morbidity that offers full-thickness rate of negative margins. It presents an excellent alternative to radical surgery for mid and proximally located lesions. We report the largest United States (US) experience in use transanal rectal carcinoids.Data patients who had undergone were prospectively collected retrospectively...
Opioid-based postsurgical analgesia exposes patients undergoing laparoscopic colectomy to elevated risk for gastrointestinal motility problems and other opioid-related adverse events (ORAEs). The purpose of our research was investigate outcomes, including opioid consumption, hospital length stay, ORAE associated with a multimodal regimen, employing single administration liposome bupivacaine as well analgesics that act by different mechanisms. We analyzed combined results from 6 Phase IV,...