Thrasyvoulos Tzellos

ORCID: 0000-0003-2356-0847
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About
Contact & Profiles
Research Areas
  • Hidradenitis Suppurativa and Treatments
  • Colorectal and Anal Carcinomas
  • Microscopic Colitis
  • Nonmelanoma Skin Cancer Studies
  • Cutaneous Melanoma Detection and Management
  • Dermatology and Skin Diseases
  • Allergic Rhinitis and Sensitization
  • Autoimmune Bullous Skin Diseases
  • Acne and Rosacea Treatments and Effects
  • Psoriasis: Treatment and Pathogenesis
  • Autoimmune and Inflammatory Disorders
  • Cancer and Skin Lesions
  • melanin and skin pigmentation
  • Proteoglycans and glycosaminoglycans research
  • Skin Protection and Aging
  • Anorectal Disease Treatments and Outcomes
  • Bone health and treatments
  • Nail Diseases and Treatments
  • Asthma and respiratory diseases
  • Urticaria and Related Conditions
  • Bone and Joint Diseases
  • Chemotherapy-related skin toxicity
  • Cutaneous lymphoproliferative disorders research
  • Hedgehog Signaling Pathway Studies
  • Oral Health Pathology and Treatment

Nordland Hospital Trust
2020-2025

University Hospital of North Norway
2014-2024

UiT The Arctic University of Norway
2018-2024

Nordland Hospital
2020-2024

National and Kapodistrian University of Athens
2023

John Wiley & Sons (United States)
2019

Hudson Institute
2019

John Wiley & Sons (United Kingdom)
2019

Oxfam
2019

Hidradenitis Suppurativa Foundation
2015

Abstract Objective Behçet's disease ( BD ) is a chronic, relapsing, inflammatory vascular with no pathognomonic test. Low sensitivity of the currently applied International Study Group ISG clinical diagnostic criteria led to their reassessment. Methods An Team for Revision Criteria (from 27 countries) submitted data from 2556 clinically diagnosed patients and 1163 controls ‐mimicking diseases or presenting at least one major sign. These were randomly divided into training validation sets....

10.1111/jdv.12107 article EN Journal of the European Academy of Dermatology and Venereology 2013-02-26

A validated tool for the dynamic severity assessment of hidradenitis suppurativa/acne inversa (HS) is lacking. To develop and validate a novel scoring system to assess HS. Delphi voting procedure was conducted among members European Hidradenitis Suppurativa Foundation (EHSF) achieve consensus towards an initial HS Severity Score System (HS4). Strengths weaknesses HS4 were examined by multicentre prospective study. Multivariate logistic regression, discriminant analysis receiver operating...

10.1111/bjd.15748 article EN British Journal of Dermatology 2017-06-21

<b><i>Background:</i></b> Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating disease, which inflicts significant burden on patients and associated with comorbid disorders, such as significantly reduced quality of life, depression, stigmatization, inactivity, working disability, impairment sexual health several cardiovascular risk factors. <b><i>Aims/Methods:</i></b> To implement an expert consensus...

10.1159/000431175 article EN Dermatology 2015-01-01

Dermoscopy is useful in evaluating skin tumours, but its applicability extends also to the field of inflammatory disorders. Plaque psoriasis (PP), dermatitis, lichen planus (LP) and pityriasis rosea (PR) are common diseases, little currently known about their dermoscopic features.To determine compare patterns associated with PP, LP PR assess validity certain criteria diagnosis PP.Patients were prospectively enrolled. The single most recently developed lesion was examined dermoscopically...

10.1111/j.1365-2133.2012.10868.x article EN British Journal of Dermatology 2012-02-01

Abstract Background Early stage mycosis fungoides (MF) is difficult to be clinically differentiated from chronic dermatitis (CD) in a high proportion of patients. Dermoscopy rapid, cheep, non‐invasive and widely used method for the evaluation skin tumours and, recently, inflammatory diseases, as well. Objective To describe dermoscopic pattern early MF compare it with features observed CD. Methods This was retrospective study. Dermoscopic images lesions that were equivocal between CD...

10.1111/j.1468-3083.2012.04499.x article EN Journal of the European Academy of Dermatology and Venereology 2012-03-09

BackgroundTetracyclines and clindamycin plus rifampicin combination therapy are both considered first-line in current hidradenitis suppurativa guidelines. However, evidence for their efficacy is drawn from small studies, often without validated outcomes.ObjectiveTo assess the 12-week of oral tetracyclines a rifampicin.MethodsA prospective, international cohort study performed between October 2018 August 2019.ResultsIn total, 63.6% included 283 patients received tetracyclines, 36.4% were...

10.1016/j.jaad.2020.12.089 article EN cc-by Journal of the American Academy of Dermatology 2021-01-20

Validated, inclusive and easy-to-use outcomes for hidradenitis suppurativa are essential both in the clinical trial setting practice. The continuous IHS4 is a validated tool that dynamically assesses nodules/abscesses/draining tunnels classifies disease severity as mild/moderate/severe. However, dichotomous often required trials reporting.To develop validate outcome based on can be used settings day-to-day practice.De-identified data from PIONEER-I -II studies were accessed through Vivli....

10.1111/jdv.18632 article EN cc-by-nc Journal of the European Academy of Dermatology and Venereology 2022-10-03

Abstract Introduction This second part of the S2k guidelines is an update 2015 S1 European guidelines. Objective These aim to provide accepted decision aid for selection, implementation and assessment appropriate sufficient therapy patients with hidradenitis suppurativa/acne inversa (HS). Methods The chapters have been selected after a Delphi procedure among experts/authors. Certain passages adopted without changes from previous version. Potential treatment complications are not included,...

10.1111/jdv.20472 article EN cc-by-nc-nd Journal of the European Academy of Dermatology and Venereology 2024-12-19

Abstract Background Melanoma disease patterns vary with patient age. Aim To evaluate sentinel lymph node biopsy (SLNB) in managing melanoma at differing ages. Methods Online prediction tools were applied to compare SLNB positivity (SLNB + ) and survival risk ages 20–80. Tübingen data used determine variations the hazard ratio of for mortality different Results Regardless tumour thickness, predicted rates markedly higher than 20‐year‐old patients. For 80‐year‐old patients, it is opposite....

10.1111/jdv.19772 article EN Journal of the European Academy of Dermatology and Venereology 2024-01-03

Abstract: Extrinsic skin ageing or ‘photoageing’, as opposed to intrinsic ageing, is the result of exposure external factors, mainly ultraviolet irradiation. Glycosaminoglycans (GAG) and particularly hyaluronic acid (HA) are major components cutaneous extracellular matrix involved in tissue repair. However, their involvement extrinsic remains elusive. In this study, we investigated expression HA its metabolizing enzymes photoexposed photoprotected human specimens, obtained from same patient....

10.1111/j.1600-0625.2009.00889.x article EN Experimental Dermatology 2009-07-10

Background : Traumatic brain injury (TBI) results in a hypermetabolic and hypercatabolic status which adequate nutrition support is essential to improve clinical outcome. The endocrine system of patient with TBI also affected may play critical role either the metabolic or immunologic response trauma. In present study, effect standard, delayed enteral feeding (DEF), compared early (within 24–48 hours) (EEF), on function patients was investigated. Methods This comparative, prospective,...

10.1177/0148607110397878 article EN Journal of Parenteral and Enteral Nutrition 2011-09-30

Hidradenitis suppurativa (HS), a chronic cutaneous disease, can negatively affect work life. This retrospective cohort study evaluates the indirect burden among employed patients with HS in U.S.A. Newly diagnosed and general HS, who were employees (age 18–64 years) from large claims database (Q1 1999 to Q1 2015), matched 1 : 5 controls. Income growth risk of leaving workforce assessed newly control cohorts 5‐year period. Income, loss days costs (absenteeism disability) 1‐year (n = 1003, mean...

10.1111/bjd.17101 article EN cc-by-nc-nd British Journal of Dermatology 2018-08-18
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