- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- High-Energy Particle Collisions Research
- Hip and Femur Fractures
- Airway Management and Intubation Techniques
- Advanced Photocatalysis Techniques
- Anesthesia and Sedative Agents
- Cardiac Arrest and Resuscitation
- Aortic aneurysm repair treatments
- Computational Physics and Python Applications
- Quantum Dots Synthesis And Properties
- Diet and metabolism studies
- Nuclear physics research studies
- 2D Materials and Applications
- Arsenic contamination and mitigation
- Copper-based nanomaterials and applications
- Respiratory Support and Mechanisms
- Cardiovascular Health and Disease Prevention
- Dark Matter and Cosmic Phenomena
- Peripheral Artery Disease Management
- Tracheal and airway disorders
- Neutrino Physics Research
Chinese PLA General Hospital
2013-2025
Guangzhou Medical University
2025
State Key Laboratory of Respiratory Disease
2025
East China Normal University
2024
Peking University
2024
Chinese People's Liberation Army
2023
Polytechnique Montréal
2017-2022
Anhui Medical University
2021-2022
Chinese People’s Liberation Army 263 hospital
2022
University of Jinan
2019-2021
Abstract Postoperative delirium (POD) is a common and severe complication in elderly patients with hip fractures. Identifying high-risk POD can help improve the outcome of We conducted retrospective study on (≥65 years age) who underwent orthopedic surgery fracture between January 2014 August 2019. Conventional logistic regression five machine-learning algorithms were used to construct prediction models POD. A nomogram for was built method. The area under receiver operating characteristic...
ABSTRACT Metastasis remains a leading cause of cancer‐related deaths, defined by complex, multi‐step process in which tumor cells spread and form secondary growths distant tissues. Despite substantial progress understanding metastasis, the molecular mechanisms driving this development effective therapies remain incompletely understood. Elucidating pathways governing metastasis is essential for discovery innovative therapeutic targets. The rapid advancements sequencing technologies expansion...
Abstract Aims To compare the performance of logistic regression and machine learning methods in predicting postoperative delirium (POD) elderly patients. Method This was a retrospective study perioperative medical data from patients undergoing non‐cardiac non‐neurology surgery over 65 years old January 2014 to August 2019. Forty‐six variables were used predict POD. A traditional five models (Random Forest, GBM, AdaBoost, XGBoost, stacking ensemble model) compared by area under receiver...
Abstract Background Postoperative delirium (POD) is a common complication among elderly patients after surgery. It unclear whether the systemic immune-inflammation index (SII) can be predictor of POD. We explored prognostic value SII in predicting POD undergoing non-neurosurgery and non-cardiac surgery large retrospective cohort. Methods enrolled between January 2014 August 2019. Univariate multivariate logistic regression analyses were performed to explore correlation as both continuous...
Abstract Background The prognostic nutritional index (PNI) is a indicator and predictor of various diseases. However it unclear whether PNI can be perioperative ischemic stroke. This study aims to evaluate the association preoperative stroke in patients undergoing non-cardiac surgery. Methods retrospective cohort included who underwent noncardiac surgery between January 2008 August 2019. were divided into ≥ 38.8 < groups according cut-off value PNI. Univariate multivariate logistic...
Postoperative delirium is a common complication in older patients, with poor long-term outcomes. This study aimed to investigate risk factors and develop predictive model for postoperative patients after major abdominal surgery. retrospectively recruited 7577 aged ≥ 65 years who underwent surgery between January 2014 December 2018 single hospital Beijing, China. Patients were divided into training cohort (n = 5303) validation 2224) univariate multivariate logistic regression analyses build...
The purpose of this research was to evaluate the prognostic significance preoperative albumin fibrinogen (AFR) for postoperative delirium (POD) in older patients with non-neurosurgical and non-cardiac surgery. retrospective cohort study included a group aged 65 above who underwent surgery at First Medical Center Chinese PLA General Hospital from January 2014 December 2021. AFR POD correlation evaluated through univariate multivariable logistic regression analysis, as well propensity score...
<sec> <title>BACKGROUND</title> Postoperative delirium (POD) is commonly encountered among older surgical patients and associated with increased healthcare costs. Comprehensive studies focusing on the economic burden of POD in China are lacking, despite rapid aging population. </sec> <title>OBJECTIVE</title> In this study, we assess changes costs Chinese who developed identify specific cost-driving factors. <title>METHODS</title> This retrospective cohort study analyzed perioperative data...
Abstract Metastasis is a major cause of cancer deaths, but the underlying molecular mechanisms remain largely unknown. Esophageal squamous cell carcinoma (ESCC) highly aggressive with poor survival, yet key kinases driving ESCC metastasis and their biological function have not been fully discovered. Here, kinase‐substrate map metastatic presented for first time by conducting phosphoproteomics analysis 60 clinical specimens. By further consolidating data CRISPR/Cas9 functional screening, LIM...
Abstract Projected revenues of cannabis concentrates and extracts in Canada will reach 5 billion dollars, which infused products account for half the total. The pharmacologically active cannabinoids accumulate crop's flowers, accounting as much 30% their dry mass, are absent from rest plant's body. To achieve a cost effective drug formulation requires optimizing processing techniques. Here, we review pre‐treatment Cannabis sativa L. , its solvent extraction, isolation metabolites. We...
Abstract Propofol is widely used as an intravenous anesthetic in clinical practice. Previous studies have indicated that propofol induces apoptosis neurons. Brain-derived neurotrophic factor (BDNF), a factor, associated with neuronal apoptosis. BDNF-AS, relatively conserved long non-coding RNA, can reverse the transcription of BDNF. This study aimed to investigate involvement BDNF-AS propofol-induced HT22 cells. cells were treated various concentrations at different time points. was silenced...
Abstract Background Laryngeal masks airway (LMA) has been increasingly used in surgical patients. However, the use of LMA laparoscopic surgeries remains controversial. The major concerns include potential risk esophageal regurgitation, aspiration, and difficulties to achieve effective ventilation. aim this study was evaluate safety effectiveness LMA® Protector™ patients undergoing surgery. Methods Patients aged 18 70 years, scheduled for were included. insertion time, successful rate,...
Abstract Removing solvents from nanoparticle solid suspensions requires the same diligence as drying pharmaceutical ingredients. nanoparticles suspension in water oxidize, sinter, and segregates on surface when they dry a furnace. Spray preserves material properties because contact times are orders of seconds; furthermore, atomized droplets ensure particles small (5 m to 20 m) dispersed. A Yamato GA‐32 (120 mm inner diameter) spray dried co‐current flow water, with content up 60 %....