A5005578972- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Lanthanide and Transition Metal Complexes
- NMR spectroscopy and applications
- Advanced NMR Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Endometrial and Cervical Cancer Treatments
- Metabolomics and Mass Spectrometry Studies
- Atomic and Subatomic Physics Research
- Functional Brain Connectivity Studies
- Electron Spin Resonance Studies
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Photoacoustic and Ultrasonic Imaging
- Neuroscience and Neuropharmacology Research
- Medical Imaging and Pathology Studies
- Acute Ischemic Stroke Management
- Liver Disease Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Colorectal Cancer Surgical Treatments
- Spectroscopy Techniques in Biomedical and Chemical Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Intracranial Aneurysms: Treatment and Complications
Philips (China)
2020-2025
Philips (Finland)
2025
Huashan Hospital
2024
Fudan University
2024
Yunnan University
2019-2023
South China Agricultural University
2023
Shanghai Ninth People's Hospital
2020
Xiamen University
2013-2019
Johns Hopkins University
2019
Public Health Agency of Canada
2014
OBJECTIVE. This study aims to assess correlations of the time from symptom onset diagnosis and treatment with disease resolution CT scores as based on findings sequential chest examinations. MATERIALS AND METHODS. Thirty patients coronavirus (COVID-19) confirmed by reverse transcription-polymerase chain reaction analysis underwent Five who did not have positive or had yet fulfilled criteria for discharge hospital were excluded. determined according lung involvement. The was recorded each...
Purpose To explore the association between type 2 diabetes mellitus (T2DM) and body composition based on magnetic resonance fat fraction (FF) mapping. Methods A total of 341 subjects, who underwent abdominal MRI examination with FF mapping were enrolled in this study, including 68 T2DM patients 273 non-T2DM patients. The FFs areas visceral adipose tissue (VAT), subcutaneous (SAT) muscle (AM) measured at level L1-L2 vertebral. bone marrow (BMAT) was determined by averaged values T12 L1...
Background and purpose Executive function impairment, a slight but noticeable cognitive deficit in mild impairment (MCI) patients, is influenced by gamma-aminobutyric acid (GABA) levels. Reduced accompanied thinning of the cerebral cortex, which has higher GABA levels than white matter. However, relationships among levels, cortical thickness, executive MCI patients have not yet been elucidated. We investigated patients. Methods In this study, total 36 sex-, age-, education-matched healthy...
Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> H-MRS the low Signal-Noise Ratio (SNR). To improve SNR, typical approach perform large number Signal Averaging (SA). The data acquisition time, however, proportional SA accordingly. A complete clinical MRS scan takes approximately 10 minutes in common setting with 128. Recently,...
Recently, hepatitis E virus has been recognized as a new transfusion-associated risk; however, its efficiency of transmission through blood products requires further investigation. Asymptomatic viremia short duration observed in donors from several European countries to the rate <1:10,000 and HEV recipients documented Japan Europe. Although RNA was detected large plasma fractionation pools used for manufacturing derived products, not demonstrated so far. In this study, we investigated...
To analyze the value of amide proton transfer (APT) weighted and intravoxel incoherent motion (IVIM) imaging in evaluation prognostic factors for rectal adenocarcinoma, compared with diffusion (DWI).Preoperative pelvic MRI data 110 patients surgical pathologically confirmed diagnosis adenocarcinoma were retrospectively evaluated. All underwent high-resolution T2-weighted (T2WI), APT, IVIM, DWI. Parameters including APT signal intensity (APT SI), pure coefficient (D), pseudo-diffusion (D*),...
Background Microsatellite instability (MSI), caused by mismatch repair (MMR) protein defects that lead to uncorrectable bases, results in the accumulation of gene mutations and ultimately tumors. Preoperative prediction MSI can provide a basis for personalized precise treatment endometrial cancer (EC) patients. Purpose To investigate amide proton transfer weighting (APTw) imaging combined with intravoxel incoherent motion (IVIM) assessment EC. Study Type Retrospective. Population A total 71...
To develop a deep learning-based method, dubbed Denoising CEST Network (DECENT), to fully exploit the spatiotemporal correlation prior image denoising.DECENT is composed of two parallel pathways with different convolution kernel sizes aiming extract global and spectral features embedded in images. Each pathway consists modified U-Net residual Encoder-Decoder network 3D convolution. Fusion 1 × utilized concatenate pathways, output DECENT noise-reduced The performance was validated numerical...
Background Conventional quantitative MRI (qMRI) scan is time‐consuming and highly sensitive to movements, posing great challenges for images of individuals with involuntary such as Huntington's disease (HD). Purpose To evaluate the potential our developed ultra‐fast qMRI technique, multiple overlapping‐echo detachment (MOLED), in overcoming head motion its capacity quantitatively assess tissue changes HD. Study Type Prospective. Phantom/Subjects A phantom comprising 13 tubes MnCl 2 at...
Objectives To explore the value of cellular microstructural mapping by IMPULSED (imaging parameters using limited spectrally edited diffusion) method in evaluating histological type and prognostic factors rectal lesions. Materials methods Sixty-six patients with lesions were enrolled this study. All subjects underwent MRI scans including conventional diffusion weighted imaging (DWI) oscillating gradient spin-echo (OGSE) pulse (PGSE) sequences. Parameters mean cell diameter (d ),...
To quantitatively analyze renal sinus fat (RSF) dysfunction in type 2 diabetes mellitus (T2DM) patients using magnetic resonance imaging (MRI) fraction (FF) and R2* mapping. The inpatients who underwent 1.5 T MRI examination (including FF mapping) of the abdomen from January 2017 to December 2023 were enrolled. RSF volume, right left kidneys mean values measured. Associations between value T2DM assessed with logistic regression. Receiver operating characteristic (ROC) curve was applied...
This study aims to investigate the feasibility of cellular microstructural mapping by diffusion MRI (IMPULSED, imaging parameters using limited spectrally edited diffusion) breast tumors, and further evaluate whether MRI-derived features is associated with prognostic factors in cancer. prospective collected 232 patients suspected tumors from March August 2023. The IMPULSED scan included acquisitions both pulsed (PGSE) oscillating (OGSE) gradient spin echo frequencies up 33 Hz. OGSE PGSE data...
Quantitative magnetic resonance imaging (qMRI) offers reliable biomarkers in clinic. Nevertheless, most qMRI methods are time-consuming and sensitive to motion. Single-shot multiple overlapping-echo detachment (MOLED) can deliver robust T2 mapping about 100 ms with high motion tolerance. However, its spatial resolution is relatively low due the limitations of signal-to-noise ratio (SNR) echo-train length. At mean time, number echoes different evolution times collected usually limited, which...
ABSTRACT Smoking and high‐altitude (HA) exposure both adversely affect human health, with smoking linked to various cancers environments causing physiological neurological changes. Although the effects of HA on brain structure function have been studied separately, their combined impact is still rarely explored. This study aims investigate interactive intrinsic activity using resting‐state functional magnetic resonance imaging (rs‐fMRI) analysed by amplitude low‐frequency fluctuations (ALFF)...
Background Hypoxia inducible factor (HIF-1α) is a major transcriptional regulating gene expression under hypoxic conditions. HIF-1α was closely correlated with the oxygenation status of tumor and could serve as an important biomarker for hypoxia, aggressiveness, or radiation resistance. High contributes to high aggressiveness poor prognosis endometrial cancer. Purpose This study aimed investigate correlations between multimodal MRI parameters (derived from amide proton transfer weighted...
<title>Abstract</title> Background No study has assessed the application of deep learning (DL) networks in combination with more advanced super-resolution (SR) reconstruction for endometrial cancer (EC) MRI and influence this methods on myometrial invasion. We aimed to evaluate performance clinical value DL-based SR image quality improvement under-sampling accelerated EC T2WI. Methods Two sets T2WI were acquired 23 volunteers low (T2<sub>LR</sub>) high (T2<sub>HR</sub>) resolution,...
<h3>BACKGROUND AND PURPOSE:</h3> The clinical practice of three-dimensional TOF-MRA, despite its capability in brain artery assessment, has been hampered by the relatively long scan time, while recent developments fast imaging techniques with random undersampling shed light on an improved balance between image quality and speed. Our aim was to evaluate effectiveness TOF-MRA accelerated compressed sensitivity encoding identify optimal acceleration factors for routine use. <h3>MATERIALS...
To investigate the value of amide proton transfer weighted (APTw) imaging combined with dynamic contrast-enhanced magnetic resonance (DCE-MRI) in predicting intermediate-risk factors deep stromal invasion (DSI) and lymphovascular vascular space (LVSI) cervical cancer.Seventy patients cancer who underwent MRI before operation from July 2019 to February 2022 were retrospectively included this study. Clinical information including age, histologic subtype etc. recorded for patients. ATPw...
Abstract Chemical exchange saturation transfer (CEST) is a versatile technique that enables noninvasive detections of endogenous metabolites present in low concentrations living tissue. However, CEST imaging suffers from an inherently signal‐to‐noise ratio (SNR) due to the decreased water signal caused by saturated spins. This limitation challenges accuracy and reliability quantification imaging. In this study, novel spatial–spectral denoising method, called BOOST (suBspace with nOnlocal...
We report the design and performance of a two-chamber thin-layer electrochemical device for in situ potential-dependent liquid NMR measurement. Liquid spectra, simultaneously recorded with cyclic voltammetry (CV), have been obtained to reveal molecular changes potentials scanning. As proof concept, redox properties 1,4-benzoquinone based systems investigated, π dimerization has identified by combining both ex analyses. This work provides new approach spectroelectrochemistry, which will...
NMR spectroscopy is a commonly used analytical technique in practical applications, and its applicability further promoted by pure chemical shift techniques based on spectral simplification for analyses. Unfortunately, magnetic field inhomogeneity caused adverse experimental conditions remains an obstacle restricting applications. In this study, we introduce new method high-resolution proton (1H) measurements inhomogeneous fields. We demonstrate that the allows one to perform analyses...
Increasing evidence indicates the involvement of GABAergic system in pathophysiology hypothyroidism. We aimed to investigate longitudinal changes brain GABA primary hypothyroidism before and after levothyroxine (L-T4) treatment. In 18 patients with hypothyroidism, we used MEGA-PRESS (Mescher-Garwood point-resolved spectroscopy) editing sequence measure levels from medial prefrontal cortex (mPFC) posterior cingulate (PCC) at baseline 6-months L-T4 Sex- age-matched healthy controls (n = 18)...
The red imported fire ant (