Lorenzo Tinti
A5064457889- Traumatic Brain Injury Research
- Psychosomatic Disorders and Their Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Epilepsy research and treatment
- Long-Term Effects of COVID-19
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Valve Diseases and Treatments
- Pharmacological Effects and Toxicity Studies
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Coronary Artery Anomalies
- Italian Literature and Culture
- Functional Brain Connectivity Studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Health, Environment, Cognitive Aging
- Infective Endocarditis Diagnosis and Management
- Linguistic Studies and Language Acquisition
- Advancements in Semiconductor Devices and Circuit Design
- CAR-T cell therapy research
- Glioma Diagnosis and Treatment
- Infectious Encephalopathies and Encephalitis
- Non-Invasive Vital Sign Monitoring
- Attention Deficit Hyperactivity Disorder
Università Cattolica del Sacro Cuore
2023-2025
Mario Negri Institute for Pharmacological Research
2022-2025
Agostino Gemelli University Polyclinic
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2024
Presbyterian Hospital
2024
New York Hospital Queens
2024
Columbia University
2024
NewYork–Presbyterian Hospital
2024
University of the Sacred Heart
2024
Anna Needs Neuroblastoma Answers
2024
<h3>Background and Objective</h3> A variety of neurological disorders has been reported as presentations or complications COVID-19 infection. The objective this study was to determine their incidence dynamics long-term functional outcome. <h3>Methods</h3> Neuro-COVID Italy a multicentre, observational, cohort with ambispective recruitment prospective follow-up. Consecutive hospitalized patients presenting new associated infection (neuro-COVID), independently from respiratory severity, were...
Although the mechanisms underlying pathophysiology of long COVID condition are still debated, there is growing evidence that autonomic dysfunction may play a role in long-term complications or persisting symptoms observed significant proportion patients after SARS-CoV-2 infection. However, studies focused on have primarily been conducted adults, while function has not yet investigated pediatric subjects. In this study, for first time, we assessed whether with present abnormalities cardiac...
To assess frequency, types, and mechanisms of comorbidities in people with epilepsy verify their association disease features outcome.This cohort study was performed 13 Italian centers nationwide distribution accurate records. Eligible patients were children adults diagnosed before December 31, 2005, followed for a minimum 10 years. Two pairs raters independently reviewed patients' records classified each comorbidity. In case disagreement, third reviewer made the final decision....
Abstract The epidemiology of coma is unknown because case ascertainment with traditional methods difficult. Here, we used crowdsourcing methodology to estimate the incidence and prevalence in UK USA. We recruited US laypeople (aged ≥18 years) who were nationally representative (i.e. matched for age, gender ethnicity according census data) USA, respectively, utilizing a platform. provided description asked survey participants if they—‘right now’ or ‘within last year’—had family member coma....
Abstract Aims Chimeric Antigen Receptor-T (CAR-T) cell infusion is a rapidly evolving antitumor therapy; however, cardiovascular (CV) complications, likely associated with cytokine release syndrome (CRS) and systemic inflammation, have been reported to occur. The CARdio-Tox study aimed at elucidating incidence determinants of cardiotoxicity related CAR-T therapy. Methods Patients blood malignancies candidate cells were prospectively evaluated by echocardiography baseline 7 30 days after...
Background: An extensive use of transesophageal echocardiography (TEE) has recently been suggested for the diagnosis infective endocarditis (IE). In this study, we investigated whether among patients with negative transthoracic (TTE), subgroups can be identified whom TEE avoided/delayed. Methods: We conducted a retrospective study 637 consecutive who underwent suspected IE. selected 375 TTE. For each patient, obtained age, sex, blood culture (BC), exams, evidence embolism, presence...
Background Transcatheter aortic valve implantation (TAVI) has become a largely used treatment for severe stenosis. There are limited data, however, about predictors of long-term prognosis in this population. In study, we assessed whether ventricular arrhythmias may predict clinical outcomes patients undergoing TAVI. Methods and results We performed 24 h ECG Holter monitoring 267 who underwent TAVI stenosis within 30 days from successful procedure. The occurrence frequent premature complexes...
Background: Detection of myocardial bridge (MB) at angiography suggests it has a role in ischaemic-related symptoms patients with angina without obstructive coronary artery disease. However, evidence that MB may cause ischaemia is limited. Methods: We studied 41 the left anterior descending and otherwise normal arteries. Fourteen arteries served as controls. All subjects underwent maximal treadmill exercise stress test (EST) under ECG monitoring. Standard speckle-tracking echocardiography...
Abstract Disorders of consciousness are neurological conditions characterized by impaired arousal and awareness self environment. Behavioural responses absent or present but fluctuate. commonly encountered as a consequence both acute chronic brain injuries, yet reliable epidemiological estimates would require inclusive, operational definitions the concept, well wider knowledge dissemination among involved professionals. Whereas several manifestations have been described, including coma,...
Abstract Background Most neurological diseases have no curative treatment; therefore, focusing on prevention is key. Continuous research to uncover the protective and risk factors associated with different crucial successfully inform strategies. eHealth has been showing promising advantages in healthcare public health may therefore be relevant facilitate epidemiological studies. Objective In this study, we performed a Delphi consensus exercise identify key screening tests development of...
Abstract Background Recent guidelines suggest an extensive role of transesophageal echocardiography (TOE) in the diagnostic work-up for suspected infective endocarditis (IE). However, negative predictive value transthoracic (TTE) remains poorly investigated. Purpose The purpose our study was to evaluate accuracy TTE ruling out IE order avoid unnecessary TOE, a more invasive and expensive exam. Methods We reviewed data 637 consecutive patients referred laboratory with diagnosis who underwent...
Background: Intracoronary acetylcholine testing may induce epicardial coronary artery spasm (CAS) or microvascular (CMVS) in patients with angina syndromes but non-obstructive disease, their causal role individual is not always clear. In this prospective, observational single-center study, we aimed to assess whether (1) the induction of myocardial ischemia/angina by electrocardiogram (ECG) exercise stress test (EST) differs between showing different results response (i.e., CAS, CMVS, no...
Hypothermia is a promising therapeutic strategy for severe vasospasm and other types of non-thrombotic cerebral ischemia, but its clinical application limited by significant systemic side effects. We aimed to develop an intraventricular device the controlled cooling cerebrospinal fluid, produce targeted hypothermia in affected hemisphere with minimal effect on temperature. An (acronym: V-COOL) was developed silico modelling, vitro testing, vivo proof-of-concept healthy Wistar rats (n = 42)....