A5001879517- Photochromic and Fluorescence Chemistry
- Immune Cell Function and Interaction
- Immune cells in cancer
- Photoreceptor and optogenetics research
- Dietary Effects on Health
- Gut microbiota and health
- Porphyrin and Phthalocyanine Chemistry
- Nutrition, Genetics, and Disease
- Synthesis of Indole Derivatives
- Diet and metabolism studies
- T-cell and B-cell Immunology
- Sulfur-Based Synthesis Techniques
- Cancer Immunotherapy and Biomarkers
- Wheat and Barley Genetics and Pathology
- Plant Disease Resistance and Genetics
- Chemical Synthesis and Reactions
- Cancer, Stress, Anesthesia, and Immune Response
- Radical Photochemical Reactions
- Organic Chemistry Cycloaddition Reactions
- Exercise and Physiological Responses
- Autoimmune and Inflammatory Disorders Research
- Bioactive natural compounds
- Nanotechnology research and applications
- Nematode management and characterization studies
- Multiple Myeloma Research and Treatments
Fudan University
2020-2024
Foshan Maternity and Child Health Care Hospital
2024
Northeast Agricultural University
2018-2022
Shandong Center for Disease Control and Prevention
2022
Jiangxi Science and Technology Normal University
2013-2016
Northwest A&F University
2014-2015
Stripe rust (Puccinia striiformis f. sp. tritici; Pst) and powdery mildew (Blumeria graminis Bgt) are important diseases of wheat (Triticum aestivum) worldwide. Similar mechanisms gene transcripts assumed to be involved in the host defense response because both pathogens biotrophic fungi. The main objective our study was identify co-regulated mRNAs that show a change expression pattern after inoculation with Pst or Bgt, specific fungal stress response. transcriptome hexaploid line N9134...
IL-10-producing regulatory B cells (IL-10 + cells), a dominant cell (Breg) subset, foster tumor progression. However, the mechanisms underlying their generation in HCC are poorly understood. Ten-eleven translocation-2 (TET2), predominant epigenetic enzyme cells, regulates gene expression by catalyzing demethylation of 5-methylcytosine into 5-hydroxymethyl cytosine (5hmC). In this study, we investigated role TET2 IL-10 and its prospects for clinical application.TET2 activation triggered...
As a safe, feasible, and inexpensive dietary intervention, fasting-mimicking diet (FMD) exhibits excellent antitumor efficacy by regulating metabolism boosting immunity. A better understanding of the specific mechanisms underlying immunoregulatory functions FMD could help improve expand clinical application FMD-mediated immunotherapeutic strategies. In this study, we aimed to elucidate role metabolic reprogramming induced in activation immunity against colorectal cancer. Single-cell RNA...
B cells have recently emerged as playing regulatory role in autoimmune diseases. We previously demonstrated that human peripheral blood CD19+CD24hiCD27+ function both healthy donors and patients with disease. However, the mechanism of this regulation is still not fully understood. In study, microarrays were utilized to compare gene expression (regulatory cells, Bregs) CD19+CD24loCD27- (non-Bregs) blood. found heat shock protein 70 (HSP70) was significantly upregulated Bregs. vitro studies...
The intestinal mucosal immune environment requires multiple cells to maintain homeostasis. Although B are among the most important cells, little is known about mechanism that they employ regulate In this study, we found CD11b + significantly accumulated in gut lamina propria and Peyer’s patches dextran sulfate sodium-induced colitis mouse models patients with ulcerative colitis. Adoptive transfer of but not −/− effectively ameliorated exhibited therapeutic effects. Furthermore, were produce...
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory disorder that occurs as consequence of immune dysregulation. HLH can be primary (familial or non-familial) secondary to infection, autoimmune disease malignancy. Malignancy-associated often accompanied by hematologic and lymphoid neoplasms. This report describes the case 3-year-old girl with an initial diagnosis acute lymphoblastic leukemia who subsequently developed during chemotherapy. She was admitted...
Metallic nanoparticles can be synthesised in living plants, which provide a friendly approach. In this work, the authors aimed to study synthesis of silver (AgNPs) Arabidopsis and two-dimensional (2D) distribution Ag other elements (Ca, P, S, Mg, CI) plant tissues. The concentrations tissues were determined by inductively coupled plasma-atomic emission spectrometer, showing that majority was retained roots. Transmission electron micrographs showed morphology AgNPs location cells....
Background In lumbo-iliac fixation, the iliac screw can be placed in several locations and directions. There is no uniform standard for placement of a single screw. Biomechanical tests finite element analyses were used to compare effect bilateral screws with three channels on pelvic stability determine best channel. Methods Five embalmed adult cadaver specimens selected. An unstable Tile C1 injury model was established. Lumbo-iliac fixation treatment left sacral Denis II fracture includes...
Abstract Introduction B cells have a central regulatory role in various diseases. While macrophages are found the disease microenvironment and interact with tissue diverse immune cells, their relationship remains poorly explored. Methods This study used an asthma animal model macrophage depletion demonstrated significant exacerbation of symptoms upon removal, coupled marked reduction IL-10+ B-cell expression. Results Further analysis revealed that interacting were M2 subtype. Furthermore,...
A new unsymmetrical photochromic diarylethene 1-(2-methyl-5-phenyl-3-thiophene)-2-[2-methyl-5-phenyl-(4-vinyl)-3-thiophene] perfluorocyclopentene ( 1 o ) has been synthesized, and its reactivity, fluorescent were also investigated. The results showed this compound exhibited reversible photochromism, undergoing cyclization cycloreversion reactions upon alternating irradiation with UV visible light in solution,Diarylethene changed the color from colorless to blue 297 nm light, which absorption...
A new unsymmetrical photochromic diarylethene [1-(1,2-dimethyl-cyano-3-pyrrole)-2-(2-methyl-5-thienyl-3-thienyl] perfluorocyclopentene (1o ) has been synthesized, and its reactivity, fluorescent were also investigated. The results showed this compound exhibited reversible photochromism, undergoing cyclization cycloreversion reactions upon alternating irradiation with UV visible light in solution,Diarylethene 1 changed the color from colorless to purple 297 nm light, which absorption maxima...
A new unsymmetrical photochromic diarylethene 1o , which is named [1-(2-methyl-benzothiophene)-2-(2-cyano-1,5-dimethyl-4-pyrryl)]perfluorocyclopentene, was synthesized. We used it to accomplish recording by optical storage technology as memory medium. Then its both in hexane solution and PMMA film kinetics experiment were investigated detail. The result indicated that this had good thermal stability exhibited reversible photochromism, changing the color from colorless violet upon appropriate...
A new unsymmetrical photochromic diarylethene 1-[(2-methyl-3-benzothiophene)]-2-[2-methyl-5-(1,3-dioxolane)-3-thienyl] perfluorocyclopentene ( 1o ) has been synthesized. In the meantime, its photochromic, kinetics and fluorescence properties were investigated in detail. The results showed this compound exhibited reversible photochromism, undergoing cyclization cycloreversion reactions upon alternating irradiation with UV visible light solution [1]. two isomers differ from each other not only...
A new unsymmetrical photochromic diarylethene 1-(3,5-dimethyl-4-isoxazolyl)-2-{2-methyl-5-[4-(1,3-dioxolane)phenyl]-3-thienyl}perfluorocyclopentene (1o) has been synthesized.Its properties have discussed systematically, including photochromic, fluorescence switch and kinetics experiments in acetonitrile solution.The result indicated that this had good thermal stability exhibited reversible photochromism, changing the color from colorless to pink solution upon appropriate irradiation with 297...
A new unsymmetrical photochromic diarylethene with thiazole ring 1-(2,5-dimethyl-3-thiazolyl)-2-[2-methyl-5-(4-hydroxymethylphenyl)-3-thienyperfluorocyclopentene ( 1o ) has been synthesized, and its properties, such as photochromism fluorescence properties were investigated. Diarylethene 1 changed the color from colorless to orange upon irradiation 297 nm UV light, in which absorption maxima observed at 487 hexane.
<p>Supplemental materials and methods</p>