A5026637968- Electronic Health Records Systems
- Biomedical Text Mining and Ontologies
- Clinical practice guidelines implementation
- Semantic Web and Ontologies
- COVID-19 Clinical Research Studies
- Primary Care and Health Outcomes
- Medical Coding and Health Information
- COVID-19 and healthcare impacts
- Healthcare Systems and Technology
- Long-Term Effects of COVID-19
- Scientific Computing and Data Management
- Healthcare Policy and Management
- COVID-19 and Mental Health
- Advanced Database Systems and Queries
- Bariatric Surgery and Outcomes
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Emergency and Acute Care Studies
- Data Quality and Management
- Nursing Diagnosis and Documentation
- Data-Driven Disease Surveillance
- Acute Myocardial Infarction Research
- Hospital Admissions and Outcomes
- Machine Learning in Healthcare
- Interpreting and Communication in Healthcare
University of Missouri
2023-2025
Texas A&M University
2025
University of Nebraska Medical Center
2013-2023
University of Nebraska at Omaha
2021-2023
University of Missouri Health System
2023
Collaborative Research Group
2021
Cohort (United Kingdom)
2021
Northern Great Plains Research Laboratory
2021
Kaiser Permanente
2020
Memorial Sloan Kettering Cancer Center
2019
The appropriate dose of aspirin to lower the risk death, myocardial infarction, and stroke minimize major bleeding in patients with established atherosclerotic cardiovascular disease is a subject controversy.Using an open-label, pragmatic design, we randomly assigned strategy 81 mg or 325 per day. primary effectiveness outcome was composite death from any cause, hospitalization for stroke, assessed time-to-event analysis. safety bleeding, also analysis.A total 15,076 were followed median...
The SAGE (Standards-Based Active Guideline Environment) project was formed to create a methodology and infrastructure required demonstrate integration of decision-support technology for guideline-based care in commercial clinical information systems. This paper describes the development innovative features Model reports our experience encoding four guidelines. Innovations include methods integrating decision support with workflow employment enterprise order sets. Using SAGE, clinician...
The HERO registry was established to support research on the impact of COVID-19 pandemic US healthcare workers. Describe experiences and effects individuals participating in registry. Cross-sectional, self-administered enrollment survey conducted from April 10 July 31, 2020. Participants worked hospitals (74.4%), outpatient clinics (7.4%), other settings (18.2%) located throughout nation. A total 14,600 exposure, viral antibody testing, diagnosis COVID-19, job burnout, physical emotional...
Abstract Objective In response to COVID-19, the informatics community united aggregate as much clinical data possible characterize this new disease and reduce its impact through collaborative analytics. The National COVID Cohort Collaborative (N3C) is now largest publicly available HIPAA limited dataset in US history with over 6.4 million patients a testament partnership of 100 organizations. Materials Methods We developed pipeline for ingesting, harmonizing, centralizing from 56...
Abstract Background Coronavirus Disease 2019 (COVID‐19) has affected every country globally, with hundreds of millions people infected the SARS‐CoV‐2 virus and over 6 million deaths to date. It is unknown how alcohol use disorder (AUD) affects severity mortality COVID‐19. AUD known increase bacterial pneumonia risk developing acute respiratory distress syndrome. Our objective determine whether individuals have increased from Methods We utilized a retrospective cohort study inpatients...
The Health Information Technology for Economic and Clinical Act of 2009 introduced the Meaningful Use program to incentivize adoption electronic health records (EHRs) in U.S. This study investigates disparities EHR interoperability between rural urban physicians context federal programs like Medicare Access CHIP Reauthorization 2015 21st Century Cures Act. A cross-sectional analysis was conducted using 2021 Quality Payment Program Experience Report Public File compare Promoting...
<h3>Importance</h3> Determining the right dosage of aspirin for secondary prevention treatment atherosclerotic cardiovascular disease (ASCVD) remains an unanswered and critical question. <h3>Objective</h3> To report rationale design a randomized clinical trial to determine optimal be used ASCVD, using innovative research method. <h3>Design, Setting, Participants</h3> This pragmatic, open-label, patient-centered, is being conducted in 15 000 patients within National Patient-Centered Clinical...
Rural communities are among the most underserved and resource-scarce populations in United States. However, there limited data on COVID-19 outcomes rural America. This study aims to compare hospitalization rates inpatient mortality SARS-CoV-2-infected persons stratified by residential rurality.
Although bariatric procedures are commonly performed in clinical practice, long-term data on the comparative effectiveness and safety of different sustained weight loss, comorbidities, adverse effects limited, especially important patient subgroups (eg, individuals with diabetes, older patients, adolescents, minority patients).The objective this study was to create a population-based cohort patients who underwent 3 procedures-adjustable gastric band (AGB), Roux-en-Y bypass (RYGB), sleeve...
Computable biomedical knowledge artifacts (CBKs) are digital objects conveying in machine-interpretable structures. As more CBKs produced and their complexity increases, the value obtained from sharing grows. Mobilizing them widely can only be achieved if findable, accessible, interoperable, reusable, trustable (FAIR+T). To help mobilize CBKs, we describe our efforts to outline metadata categories make FAIR+T.We examined literature regarding with potential FAIR+T. We also available online...
Background Hypertension and diabetes are associated with increased COVID-19 severity. The association between level of control these conditions severity is less well understood. Methods Results This retrospective cohort study identified adults COVID-19, March 2020 to February 2022, in 43 US health systems the National Patient-Centered Clinical Research Network. was categorized as blood pressure (BP) <130/80, 130 139/80 89, 140 159/90 99, or ≥160/100 mm Hg, glycated hemoglobin <7%, 7% <9%,...
<title>Abstract</title> Although social determinants of health (SDH) significantly impact outcomes, reliable data on SDH has not been widely accessible. Despite recent efforts to integrate more individual-level (I-SDH) into electronic records, the available sources that can be accessed at scale remain predominantly community-level, structured (S-SDH). An alternative, though underutilized, strategy for collecting is link with third-party consumer databases have accumulated socioeconomic...
Abstract Background An increasing number of studies have described new and persistent symptoms conditions as potential post-acute sequelae SARS-CoV-2 infection (PASC). However, it remains unclear whether certain or occur more frequently among persons with compared those never infected SARS-CoV-2. We the occurrence specific COVID-associated PASC 31- to 150-day following a test adults children positive negative results. Methods conducted retrospective cohort study using electronic health...
Background The National Patient-Centered Clinical Research Network Blood Pressure Control Laboratory Surveillance System was established to identify opportunities for blood pressure (BP) control improvement and provide a mechanism tracking longitudinally. Methods Results We conducted serial cross-sectional study with queries against standardized electronic health record data in the (PCORnet) common model returned by 25 participating US systems. Queries produced BP metrics adults...
Coronavirus disease 2019 (COVID-19) is now the third leading cause of death in United States. Malnutrition hospitalized patients increases risk complications. However, effect malnutrition on outcomes infected unclear. This study aims to identify impact mortality and adverse hospital events with COVID-19.
Background While COVID-19 vaccines reduce adverse outcomes, post-vaccination SARS-CoV-2 infection remains problematic. We sought to identify community factors impacting risk for breakthrough infections (BTI) among fully vaccinated persons by rurality. Methods conducted a retrospective cohort study of US adults sampled between January 1 and December 20, 2021, from the National COVID Cohort Collaborative (N3C). Using Kaplan-Meier Cox-Proportional Hazards models adjusted demographic differences...
Less than 20% of hospitals in the US have an electronic health record (EHR). In this qualitative study, we examine perspectives both academic and private physicians administrators as stakeholders, their alignment, to explore on use technology clinical environment.Focus groups were conducted with 74 participants who asked a series open-ended questions. Grounded theory was used analyze transcribed data build convergent themes. The relevance importance themes constructed by examining frequency,...
Objective This research investigated the use of SNOMED CT to represent diagnostic tissue morphologies and notable architectures typically found within a pathologist's microscopic examination report identify gaps in expressivity for anatomic pathology. Methods 24 breast biopsy cases were reviewed by two board certified surgical pathologists who independently described diagnostically important observed examination. In addition, comments details extracted from original pathology report. 95...
Clinical research data warehouses are largely populated from information extracted electronic health records (EHRs). While these provide about a patient's medications, laboratory results, diagnoses, and history, her social, economic, environmental determinants of also major contributing factors in readmission, morbidity, mortality often absent or unstructured the EHR. Details socioeconomic status may be found U.S. census. To facilitate researching impacts on outcomes, clinical must linked...